Abstract
A clinical and instrumental study with a prospective, longitudinal, and double blind design was carried out to determine the effect of a phytotherapeutic flavonoid agent (Cellasene®) on microcirculation and lipedema in patients with edematous fibrosclerotic panniculopathy. Clinical results showed an improvement in symptoms and signs in the group that received the active medication. The Echo-Doppler study shows an improvement of the lipoedema conditions in 70.2% of the patients with reductions ranging from 18% to 26% of the skin muscular fascia diameter who received the active medication. Videocapillaroscopy with digital image processing detected a 43 ± 5% benefit in vertical capillary density.
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