Abstract
Purpose
: To assess whether the use of collagens with lipografts improves graft survival.
Materials and Methods
: Thirty isogenic New Zealand rabbits were injected in the auricular area with either autologous fat alone or autologous fat associated with collagen. The animals were evaluated at 7, 30, and 90 days by histologic and morphometric methods together with measurements of the graft area and the number of adipocytes.
Results
: Addition of collagen to the lipoinjection reduced the local inflammatory reaction and improved the graft's survival; e.g., for stress urinary incontinence.
Conclusion
: These results suggest that it is possible to increase the survival rate of the lipografts and improve their clinical applicability.
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