Abstract
We report on two military trainees who experienced anaphylaxis following an injection of benzathine penicillin G (BPG). A total of 9203 trainees received a prophylactic dose of BPG over a 6-month period for an incidence rate of 0.022%. One of the trainees experienced biphasic or recurrent anaphylaxis. We discuss the issue of management of anaphylaxis following an injection of a depot form of penicillin especially with regards to biphasic anaphylaxis. (Pediatr Asthma Allergy Immunol 2000;14[4]:329–332.)
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