Aoki, Y., H. Sato, N. Nishimura et al. (2001). “Accelerated DNA Adduct Formation in the Lung of the Nrf2 Knockout Mouse Exposed to Diesel Exhaust. ” Toxicol Appl Pharmacol173: 154—60.
2.
Enomoto, A., K. Itoh, E. Nagayoshi et al. (2001). “High Sensitivity of Nrf2 Knockout Mice to Acetaminophen Hepatotoxicity Associated with Decreased Expression of ARE-Regulated Drug Metabolizing Enzymes and Antioxidant Genes. ” Toxicol Sci59: 169—77.
3.
Ishii, T., K. Itoh, S. Takahashi et al. (2000). “Transcription Factor Nrf2 Coordinately Regulates a Group of Oxidative Stress-Inducible Genes in Macrophages. ” J Biol Chem275: 16023—9.
4.
Itoh, K., T. Chiba, S. Takahashi et al. (1997). “An Nrf2/small Maf Heterodimer Mediates the Induction of Phase II Detoxifying Enzyme Genes Through Antioxidant Response Elements.” Biochem Biophys Res Commun236: 313—22.
5.
Itoh, K., N. Wakabayashi, Y. Katoh et al. (1999). “Keap1 Represses Nuclear Activation of Antioxidant Responsive Elements by Nrf2 Through Binding to the Amino-Terminal Neh2 Domain.” Genes Dev13: 76—86.
6.
Ramos-Gomez, M., M.K. Kwak, P.M. Dolan et al. (2001). “From the Cover: Sensitivity to Carcinogenesis is Increased and Chemoprotective Efficacy of Enzyme Inducers is Lost in nrf2 Transcription Factor-Deficient Mice.” Proc Natl Acad Sci USA98: 3410—15.