Expression of Base Excision DNA Repair Genes is a Sensitive Biomarker for In Vivo Detection of Chemical-Induced Chronic Oxidative Stress

Helbock, H.J. , K.B. Beckman , M.K. Shigenaga , P.B. Walter , A.A. Woodall , H.C. Yeo , and B.N. Ames (1998). “DNA Oxidation Matters—the HPLC-Electrochemical Detection Assay of 8-oxo-Deoxyguanosine and 8-oxo-guanine.” Proc Natl Acad Sci USA 95: 288—93.

Marnett, L.J. (2000). “Oxyradicals and DNA Damage. ” Carcinogenesis 21: 361—70.

Rusyn, I. , M.F. Denissenko , V.A. Wong , B.E. Butterworth , M.L. Cunningham , P.B. Upton , R.G. Thurman , and J.A. Swenberg (2000). “Expression of Base Excision Repair Enzymes in Rat and Mouse Liver is Induced by Peroxisome Proliferators and is Dependent Upon Carcinogenic Potency.” Carcinogenesis 21: 2141—5.

Rusyn, I. , M.L. Rose , H.K. Bojes , and R.G. Thurman (2000). “Novel Role of Oxidants in the Molecular Mechanism of Action of Peroxisome Proliferators.” Antiox Redox Signal 2: 607—21.