In the course of a series of blocks of the ulnar and lateral popliteal nerves of volunteers a study was made of the manner in which the responses of the subject to sensory stimulation become progressively altered and finally obliterated. These changes are described, together with the manner of recovery, and an account is given of various sensations induced by the blocking and the recovery processes. The relevant literature is briefly reviewed and possible factors involved in these phenomena are discussed.
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