Fine Cuts of Empathy and the Amygdala: Dissociable Deficits in Psychopathy and Autism

Abstract

In the current paper, the “fine cuts” approach advocated by Uta Frith is applied to our understanding of empathy and amygdala dysfunction in two disorders, psychopathy and autism. A fine cut is made between cognitive (i.e., Theory of Mind) and emotional empathy. The literature with respect to psychopathy and autism and these two functions is then considered. A fine cut is also made between the amygdala's role in stimulus–reinforcement association and specific aspects of social cognition. Again the literature with respect to psychopathy and autism and these two functions of the amygdala is considered. It is concluded that while both conditions can be considered disorders of social cognition, fine cuts can be made dissociating the impairments associated with each.

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References

Adolphs

(2002). Neural systems for recognizing emotion. Current Opinion in Neurobiology 12, 169–177.

Adolphs

(2003). Is the human amygdala specialized for processing social information?. Annals of the New York Academy of Sciences 985, 326–340.

Adolphs

Baron-Cohen

Tranel

(2002). Impaired recognition of social emotions following amygdala damage. Journal of Cognitive Neuroscience 14, 1264–1274.

Adolphs

Gosselin

Buchanan

T. W.

Tranel

Schyns

Damasio

A. R.

(2005). A mechanism for impaired fear recognition after amygdala damage. Nature 433, 68–72.

Adolphs

Sears

Piven

(2001). Abnormal processing of social information from faces in autism. Journal of Cognitive Neuroscience 13, 232–240.

Adolphs

Tranel

Damasio

A. R.

(1998). The human amygdala in social judgment. Nature 393, 470–474.

Amaral

D. G.

(2003). The amygdala, social behavior, and danger detection. Annals of the New York Academy of Sciences 1000, 337–347.

Amaral

D. G.

Bauman

M. D.

Capitanio

J. P.

Lavenex

Mason

W. A.

Mauldin-Jourdain

M. L.

(2003). The amygdala: Is it an essential component of the neural network for social cognition?. Neuropsychologia 41, 517–522.

American Psychiatric Association Diagnostic and statistical manual of mental disorders. ((4). Washington, DC: Author 1994.

10.

Arsenio

W. F.

Fleiss

(1996). Typical and behaviourally disruptive children's understanding of the emotion consequences of socio-moral events. British Journal of Developmental Psychology 14, 173–186.

11.

Ashwin

Baron-Cohen

Wheelwright

O'Riordan

Bullmore

E. T.

(2007). Differential activation of the amygdala and the “social brain” during fearful face-processing in Asperger syndrome. Neuropsychologia 45, 2–14.

12.

Attwood

Frith

Hermelin

(1988). The understanding and use of interpersonal gestures by autistic and Down's syndrome children. Journal of Autism and Developmental Disorders 18, 241–257.

13.

Bachevalier

(1994). Medial temporal lobe structures and autism: A review of clinical and experimental findings. Neuropsychologia 32, 627–648.

14.

Baron-Cohen

(2006). The hyper-systemizing, assortative mating theory of autism. Progress in Neuropsychopharmacology and Biological Psychiatry 30, 865–872.

15.

Baron-Cohen

Leslie

A. M.

Frith

(1985). Does the autistic child have a “theory of mind”?. Cognition 21, 37–46.

16.

Baron-Cohen

Ring

H. A.

Bullmore

E. T.

Wheelwright

Ashwin

Williams

S. C.

(2000). The amygdala theory of autism. Neuroscience Biobehavior Review 24, 355–364.

17.

Baron-Cohen

Ring

H. A.

Wheelwright

Bullmore

E. T.

Brammer

M. J.

Simmons

(1999). Social intelligence in the normal and autistic brain: An fMRI study. European Journal of Neuroscience 11, 1891–1898.

18.

Baron-Cohen

Wheelwright

Joliffe

(1997). Is there a “language of the eyes”? Evidence from normal adults, and adults with autism or Asperger syndrome. Visual Cognition 4, 311–331.

19.

Bauman

M. D.

Lavenex

Mason

W. A.

Capitanio

J. P.

Amaral

D. G.

(2004). The development of social behavior following neonatal amygdala lesions in rhesus monkeys. Journal of Cognitive Neuroscience 16, 1388–1411.

20.

Bauman

M. D.

Toscano

J. E.

Mason

W. A.

Lavenex

Amaral

D. G.

(2006). The expression of social dominance following neonatal lesions of the amygdala or hippocampus in rhesus monkeys (Macaca mulatta). Behavioral Neuroscience 120, 749–760.

21.

Baxter

M. G.

Murray

E. A.

(2002). The amygdala and reward. Nature Reviews Neuroscience 3, 563–573.

22.

Bechara

Tranel

Damasio

Adolphs

Rockland

Damasio

A. R.

(1995). Double dissociation of conditioning and declarative knowledge relative to the amygdala and hippocampus in humans. Science 269, 1115–1118.

23.

Bernier

Dawson

Panagiotides

Webb

(2005). Individuals with autism spectrum disorder show normal responses to a fear potential startle paradigm. Journal of Autism and Developmental Disorders 35, 1–9.

24.

Birbaumer

Veit

Lotze

Erb

Hermann

Grodd

(2005). Deficient fear conditioning in psychopathy: A functional magnetic resonance imaging study. Archives of General Psychiatry 62, 799–805.

25.

Blair

R. J. R.

(1995). A cognitive developmental approach to morality: Investigating the psychopath. Cognition 57, 1–29.

26.

Blair

R. J. R.

(1996). Brief report: Morality in the autistic child. Journal of Autism and Developmental Disorders 26, 571–579.

27.

Blair

R. J. R.

(2001). Neuro-cognitive models of aggression, the antisocial personality disorders and psychopathy. Journal of Neurology, Neurosurgery & Psychiatry 71, 727–731.

28.

Blair

R. J. R.

(2003). Facial expressions, their communicatory functions and neuro-cognitive substrates. Philosophical Transactions of the Royal Society of London, series B 358, 561–572.

29.

Blair

R. J. R.

(2004). The roles of orbital frontal cortex in the modulation of antisocial behavior. Brain and Cognition 55, 198–208.

30.

Blair

R. J. R.

(2005). Responding to the emotions of others: Dissociating forms of empathy through the study of typical and psychiatric populations. Consciousness and Cognition 14, 698–718.

31.

Blair

R. J. R.

(2006). Dissociable systems for empathy. Bock

Goode

Empathy and fairness. Chichester, UK: John Wiley and Sons 134–141.

32.

Blair

R. J. R.

Colledge

Murray

Mitchell

D. G.

(2001). A selective impairment in the processing of sad and fearful expressions in children with psychopathic tendencies. Journal of Abnormal Child Psychology 29, 491–498.

33.

Blair

R. J. R.

Frith

Smith

Abell

Cipolotti

(2002). Fractionation of visual memory: Agency detection and its impairment in autism. Neuropsychologia 40, 108–118.

34.

Blair

R. J. R.

Marsh

A. A.

Finger

Blair

K. S.

Luo

(2006). Neuro-cognitive systems involved in morality. Philosophical Explorations 9, 13–27.

35.

Blair

R. J. R.

Mitchell

D. G. V.

Blair

K. S.

(2005). The psychopath: Emotion and the brain Oxford, UK: Blackwell.

36.

Blair

R. J. R.

Mitchell

D. G. V.

Colledge

Leonard

R. A.

Shine

J. H.

Murray

L. K.

(2004). Reduced sensitivity to other's fearful expressions in psychopathic individuals. Personality & Individual Differences 37, 1111–1121.

37.

Blair

R. J. R.

Morris

J. S.

Frith

C. D.

Perrett

D. I.

Dolan

(1999). Dissociable neural responses to facial expressions of sadness and anger. Brain 122, 883–893.

38.

Blair

R. J. R.

Sellars

Strickland

Clark

Williams

Smith

(1996). Theory of mind in the psychopath. Journal of Forensic Psychiatry 7, 15–25.

39.

Bormann-Kischkel

Vilsmeier

Baude

(1995). The development of emotional concepts in autism. Journal of Child Psychology and Psychiatry 36, 1243–1259.

40.

Boucher

Lewis

(1992). Unfamiliar face recognition in relatively able autistic children. Journal of Child Psychology and Psychiatry 33, 843–859.

41.

Buchel

Dolan

R. J.

(2000). Classical fear conditioning in functional neuroimaging. Current Opinions in Neurobiology 10, 219–223.

42.

Buchel

Morris

Dolan

R. J.

Friston

K. J.

(1998). Brain systems mediating aversive conditioning: An event-related fMRI study. Neuron 20, 947–957.

43.

Castelli

Frith

Happé

Frith

(2002). Autism, Asperger syndrome and brain mechanisms for the attribution of mental states to animated shapes. Brain 125, 1839–1849.

44.

Castelli

Happé

Frith

(2000). Movement and mind: A functional imaging study of perception and interpretation of complex intentional movement patterns. Neuroimage 12, 314–325.

45.

Cleckley

(1941). The mask of sanity. ((1). St Louis, MO: Mosby.

46.

Critchley

H. D.

Daly

E. M.

Bullmore

E. T.

Williams

S. C.

Van Amelsvoort

Robertson

D. M.

(2000). The functional neuroanatomy of social behaviour: Changes in cerebral blood flow when people with autistic disorder process facial expressions. Brain 123, 2203–2212.

47.

Cubero

Thiele

T. E.

Bernstein

I. L.

(1999). Insular cortex lesions and taste aversion learning: Effects of conditioning method and timing of lesion. Brain Research 839, 323–330.

48.

Dadds

M. R.

Perry

Hawes

D. J.

Merz

Riddell

A. C.

Haines

D. J.

(2006). Attention to the eyes and fear-recognition deficits in child psychopathy. British Journal of Psychiatry 189, 280–281.

49.

Davis

(2000). The role of the amygdala in conditioned and unconditioned fear and anxiety. Aggleton

J. P.

The amygdala: A functional analysis. Oxford, UK: Oxford University Press 289–310.

50.

Dolan

Fullam

(2004). Theory of mind and mentalizing ability in antisocial personality disorders with and without psychopathy. Psychological Medicine 34, 1093–1102.

51.

Dolan

Fullam

(2006). Face affect recognition deficits in personality-disordered offenders: Association with psychopathy. Psychological Medicine 36, 1563–1569.

52.

Emery

N. J.

Capitanio

J. P.

Mason

W. A.

Machado

C. J.

Mendoza

S. P.

Amaral

D. G.

(2001). The effects of bilateral lesions of the amygdala on dyadic social interactions in rhesus monkeys (Macaca mulatta). Behavioral Neuroscience 115, 515–544.

53.

Everitt

B. J.

Cardinal

R. N.

Parkinson

J. A.

Robbins

T. W.

(2003). Appetitive behavior: Impact of amygdala-dependent mechanisms of emotional learning. Annals of the New York Academy of Sciences 985, 233–250.

54.

Fitzgerald

D. A.

Angstadt

Jelsone

L. M.

Nathan

P. J.

Phan

K. L.

(2006). Beyond threat: Amygdala reactivity across multiple expressions of facial affect. Neuroimage 30, 1441–1448.

55.

Fletcher

P. C.

Happé

Frith

Baker

S. C.

Dolan

R. J.

Frackowiak

R. S.

(1995). Other minds in the brain: A functional imaging study of “theory of mind” in story comprehension. Cognition 57, 109–128.

56.

Flor

Birbaumer

Hermann

Ziegler

Patrick

C. J.

(2002). Aversive Pavlovian conditioning in psychopaths: Peripheral and central correlates. Psychophysiology 39, 505–518.

57.

Frick

P. J.

(1995). Callous-unemotional traits and conduct problems: A two-factor model of psychopathy in children. Issues in Criminological and Legal Psychology 24, 47–51.

58.

Frick

P. J.

Hare

R. D.

(2001). The antisocial process screening device Toronto, Canada: Multi-Health Systems.

59.

Frith

C. D.

Frith

(1999). Interacting minds: A biological basis. Science 286, 1692–1695.

60.

Frith

C. D.

Frith

(2006). The neural basis of mentalizing. Neuron 50, 531–534.

61.

Frith

(1989). Autism: Explaining the enigma Oxford, UK: Blackwell.

62.

Frith

C. D.

(2003). Development and neurophysiology of mentalizing. Philosophical Transactions of the Royal Society B: Biological Sciences 358, 459–473.

63.

Frith

Happé

(1994). Autism: Beyond “theory of mind”. Cognition 50, 115–132.

64.

Frith

Happé

(2005). Autism spectrum disorder. Current Biology 15, R786–790.

65.

Gaigg

S. B.

Bowler

D. M.

(2007). Differential fear conditioning in Asperger's syndrome: Implications for an amygdala theory of autism. Neuropsychlogia 45, 2125–2134.

66.

Goel

Grafman

Sadato

Hallett

(1995). Modeling other minds. Neuroreport 11, 1741–1746.

67.

Gordon

H. L.

Baird

A. A.

End

(2004). Functional differences among those high and low on a trait measure of psychopathy. Biological Psychiatry 56, 516–521.

68.

Grant

C. M.

Boucher

Riggs

K. J.

Grayson

(2005). Moral understanding in children with autism. Autism 9, 317–331.

69.

Happé

Ehlers

Fletcher

Frith

Johansson

Gillberg

(1996). “Theory of mind” in the brain. Neuroreport 8, 197–201.

70.

Happé

F. G. E.

Frith

(1996a). The neuropsychology of autism. Brain 1377–1400.

71.

Happé

F. G. E.

Frith

(1996b). Theory of mind and social impairment in children with conduct disorder. British Journal of Developmental Psychology 14, 385–398.

72.

Hare

R. D.

(1991). The Hare Psychopathy Checklist–Revised Toronto, Canada: Multi-Health Systems.

73.

Hare

R. D.

(2003). Hare Psychopathy Checklist–Revised (PCL-R). ((2nd ed.)). Toronto, Canada: Multi Health Systems.

74.

Harpur

T. J.

Hakstian

A. R.

Hare

R. D.

(1988). The factor structure of the Psychopathy Checklist. Journal of Consulting and Clinical Psychology 56, 741–747.

75.

Herba

Phillips

(2004). Annotation: Development of facial expression recognition from childhood to adolescence: Behavioural and neurological perspectives. Journal of Child Psychology and Psychiatry 45, 1185–1198.

76.

Herpertz

S. C.

Werth

Lukas

Qunaibi

Schuerkens

Kunert

H. J.

(2001). Emotion in criminal offenders with psychopathy and borderline personality disorder. Archives of General Psychiatry 58, 737–745.

77.

Hill

E. L.

Frith

(2003). Understanding autism: Insights from mind and brain. Philosophical Transactions of the Royal Society, Series B 358, 281–289.

78.

Hobson

(1986). The autistic child's appraisal of expressions of emotion. Journal of Child Psychology and Psychiatry 27, 321–342.

79.

Hobson

R. P.

(1993). Autism and the development of mind Hove, UK: Lawrence Erlbaum Associates.

80.

Hooker

C. I.

Germine

L. T.

Knight

R. T.

D'Esposito

(2006). Amygdala response to facial expressions reflects emotional learning. Journal of Neuroscience 26, 8915–8922.

81.

Howard

M. A.

Cowell

P. E.

Boucher

Broks

Mayes

Farrant

(1931–1935). Convergent neuroanatomical and behavioural evidence of an amygdala hypothesis of autism. Neuroreport 11.

82.

Hughes

Dunn

White

(1998). Trick or treat?: Uneven understanding of mind and emotion and executive dysfunction in “hard-to-manage” preschoolers. Journal of Child Psychology and Psychiatry 39, 981–994.

83.

Hughes

Ensor

(2006). Behavioural problems in 2-year-olds: Links with individual differences in theory of mind, executive function and harsh parenting. Journal of Child Psychology and Psychiatry 47, 488–497.

84.

Hume

(1967). A treatise of human nature Oxford, UK: Oxford University Press (Original work published 1740).

85.

Humphreys

Minshew

Leonard

G. L.

Behrmann

(2007). A fine-grained analysis of facial expression processing in high-functioning adults with autism. Neuropsychologia 45, 685–695.

86.

Kanner

(1943). Autistic disturbances of affective contact. Nervous Child 2, 217–250.

87.

Kennett

(2002). Autism, empathy and moral agency. The Philosophical Quarterly 52, 340–357.

88.

Kiehl

K. A.

(2006). A cognitive neuroscience perspective on psychopathy: Evidence for paralimbic system dysfunction. Psychiatry Research 142, 107–128.

89.

Klin

Jones

Schultz

Volkmar

Cohen

(2002). Visual fixation patterns during viewing of naturalistic social situations as predictors of social competence in individuals with autism. Archives of General Psychiatry 59, 809–816.

90.

Klin

Sparrow

S. S.

de Bildt

Cicchetti

D. V.

Cohen

D. J.

Volkmar

F. R.

(1999). A normed study of face recognition in autism and related disorders. Journal of Autism and Developmental Disabilities 29, 499–508.

91.

Kling

A. S.

Brothers

L. A.

(1992). The amygdala and social behaviour. Aggleton

J. P.

The amygdala: Neurobiological aspects of emotion, memory, and mental dysfunction. New York: Wiley 353–378.

92.

Kosson

D. S.

Suchy

Mayer

A. R.

Libby

(2002). Facial affect recognition in criminal psychopaths. Emotion 2, 398–411.

93.

LaBar

K. S.

Crupain

M. J.

Voyvodic

J. T.

McCarthy

(2003). Dynamic perception of facial affect and identity in the human brain. Cerebral Cortex 13, 1023–1033.

94.

LaBar

K. S.

Gatenby

J. C.

Gore

J. C.

LeDoux

J. E.

Phelps

E. A.

(1998). Human amygdala activation during conditioned fear acquisition and extinction: A mixed-trial fMRI study. Neuron 20, 937–945.

95.

LeDoux

(1998). The emotional brain New York: Weidenfeld & Nicolson.

96.

LeDoux

J. E.

(2000). The amygdala and emotion: A view through fear. Aggleton

J. P.

The amygdala: A functional analysis. Oxford, UK: Oxford University Press 289–310.

97.

Leslie

A. M.

Thaiss

(1992). Domain specificity in conceptual development: Neuropsychological evidence from autism. Cognition 43, 225–251.

98.

Levenston

G. K.

Patrick

C. J.

Bradley

M. M.

Lang

P. J.

(2000). The psychopath as observer: Emotion and attention in picture processing. Journal of Abnormal Psychology 109, 373–386.

99.

Lissek

Powers

A. S.

McClure

E. B.

Phelps

E. A.

Woldehawariat

Grillon

(2005). Classical fear conditioning in the anxiety disorders: A meta-analysis. Behavior Research and Therapy 43, 1391–1424.

100.

Luo

Holroyd

Jones

Hendler

Blair

(2007). Neural dynamics for facial threat processing as revealed by gamma band synchronization using MEG. Neuroimage 34, 839–847.

101.

Lykken

D. T.

(1957). A study of anxiety in the sociopathic personality. Journal of Abnormal and Social Psychology 55, 6–10.

102.

Marsh

A. A.

Blair

R. J. R.

Antisocial behavior is associated with specific deficits in recognition of the fear facial expression: A meta-analysis.

103.

Mineka

Cook

(1993). Mechanisms involved in the observational conditioning of fear. Journal of Experimental Psychology: General 122, 23–38.

104.

Montagne

van Honk

Kessels

R. P. C.

Frigerio

Burt

van Zandvoort

M. J. E.

(2005). Reduced efficiency in recognising fear in subjects scoring high on psychopathic personality characteristics. Personality and Individual Differences 38, 5–11.

105.

Moore

D. G.

(2001). Reassessing emotion recognition performance in people with mental retardation: A review. American Journal on Mental Retardation 106, 481–502.

106.

Morris

J. S.

Frith

C. D.

Perrett

D. I.

Rowland

Young

A. W.

Calder

A. J.

(1996). A differential response in the human amygdala to fearful and happy facial expressions. Nature 383, 812–815.

107.

Morris

J. S.

Ohman

Dolan

A subcortical pathway to the right amygdala mediating “unseen” fear. Proceedings of the National Academy of Sciences USA 1999 96 1680–1685.

108.

Newman

J. P.

(1998). Psychopathic behaviour: An information processing perspective. Cooke

D. J.

Forth

A. E.

Hare

R. D.

Psychopathy: Theory, research and implications for society. Dordrecht, The Netherlands: Kluwer Academic Publishers 81–105.

109.

Nucci

L. P.

Herman

(1982). Behavioral disordered children's conceptions of moral, conventional, and personal issues. Journal of Abnormal Child Psychology 10, 411–425.

110.

Ozonoff

Pennington

Rogers

(1990). Are there emotion perception deficits in young autistic children?. Journal of Child Psychology and Psychiatry 31, 343–363.

111.

Patrick

C. J.

(1994). Emotion and psychopathy: Startling new insights. Psychophysiology 31, 319–330.

112.

Patrick

C. J.

Cuthbert

B. N.

Lang

P. J.

(1994). Emotion in the criminal psychopath: Fear image processing. Journal of Abnormal Psychology 103, 523–534.

113.

Perner

Leekam

(2008). The curious incident of the photo that was accused of being false: Issues of domain specificity in development, autism, and brain imaging. Quarterly Journal of Experimental Psychology 61, 76–89.

114.

Phillips

M. L.

Young

A. W.

Scott

S. K.

Calder

A. J.

Andrew

Giampietro

Neural responses to facial and vocal expressions of fear and disgust. Proceedings of the Royal Society of London, Series B 1998 265 1809–1817.

115.

Pierce

Muller

R. A.

Ambrose

Allen

Courchesne

(2001). Face processing occurs outside the fusiform “face area” in autism: Evidence from functional MRI. Brain 124, 2059–2073.

116.

Pizzagalli

Regard

Lehmann

(1999). Rapid emotional face processing in the human right and left brain hemispheres: An ERP study. Neuroreport 10, 2691–2698.

117.

Prather

M. D.

Lavenex

Mauldin-Jourdain

M. L.

Mason

W. A.

Capitanio

J. P.

Mendoza

S. P.

(2001). Increased social fear and decreased fear of objects in monkeys with neonatal amygdala lesions. Neuroscience 106, 653–658.

118.

Prior

Dahlstrom

Squires

(1990). Autistic children's knowledge of thinking and feeling states in other people. Journal of Autism and Developmental Disorders 31, 587–602.

119.

Richell

R. A.

Mitchell

D. G.

Newman

Leonard

Baron-Cohen

Blair

R. J.

(2003). Theory of mind and psychopathy: Can psychopathic individuals read the “language of the eyes”?. Neuropsychologia 41, 523–526.

120.

Richell

R. A.

Mitchell

D. G. V.

Peschardt

K. S.

Winston

J. S.

Leonard

Dolan

R. J.

(2005). Trust and distrust: The perception of trustworthiness of faces in psychopathic and non-psychopathic offenders. Personality and Individual Differences 38, 1735–1744.

121.

Rogers

Viding

Blair

J. R.

Frith

Happé

(2006). Autism spectrum disorder and psychopathy: Shared cognitive underpinnings or double hit?. Psychological Medicine 36, 1789–1798.

122.

Rolls

E. T.

(1999). The brain and emotion Oxford, UK: Oxford University Press.

123.

Rosvold

Mirsky

Pribram

(1954). Influence of amygdalectomy on social behavior in monkeys. Journal of Comparative Physiology A 47, 173–178.

124.

Rozin

Haidt

McCauley

C. R.

(1993). Disgust. Lewis

Haviland

J. M.

Handbook of emotions. New York: The Guilford Press 575–594.

125.

Rutter

(2005). Commentary: What is the meaning and utility of the psychopathy concept?. Journal of Abnormal Child Psychology 33, 499–503.

126.

Schultz

R. T.

Gauthier

Klin

Fulbright

R. K.

Anderson

A. W.

Volkmar

(2000). Abnormal ventral temporal cortical activity during face discrimination among individuals with autism and Asperger syndrome. Archives of General Psychiatry 57, 331–340.

127.

Sprengelmeyer

Rausch

Eysel

U. T.

Przuntek

Neural structures associated with the recognition of facial basic emotions. Proceedings of the Royal Society of London, Series B 1998 265 1927–1931.

128.

Steele

Joseph

R. M.

Tager-Flusberg

(2003). Brief report: Developmental change in theory of mind abilities in children with autism. Journal of Autism and Developmental Disorders 33, 461–467.

129.

Stone

V. E.

Baron-Cohen

Calder

Keane

Young

(2003). Acquired theory of mind impairments in individuals with bilateral amygdala lesions. Neuropsychologia 41, 209–220.

130.

Sutton

Reeves

Keogh

(2000). Disruptive behaviour, avoidance of responsibility and theory of mind. British Journal of Developmental Psychology 18, 1–11.

131.

Sutton

Smith

P. K.

Swettenham

(1999). Social cognition and bullying: Social inadequacy or skilled manipulation?. British Journal of Developmental Psychology 17, 435–450.

132.

Veit

Flor

Erb

Hermann

Lotze

Grodd

(2002). Brain circuits involved in emotional learning in antisocial behavior and social phobia in humans. Neuroscience Letters 328, 233–236.

133.

Vuilleumier

Armony

J. L.

Driver

Dolan

R. J.

(2003). Distinct spatial frequency sensitivities for processing faces and emotional expressions. Nature Neuroscience 6, 624–631.

134.

Wang

A. T.

Dapretto

Hariri

A. R.

Sigman

Bookheimer

S. Y.

(2004). Neural correlates of facial affect processing in children and adolescents with autism spectrum disorder. Journal of the American Academy of Child and Adolescent Psychiatry 43, 481–490.

135.

White

Hill

Winston

Frith

(2006). An islet of social ability in Asperger syndrome: Judging social attributes from faces. Brain and Cognition 61, 69–77.

136.

Widom

C. S.

(1976). Interpersonal and personal construct systems in psychopaths. Journal of Consulting and Clinical Psychology 44, 614–623.

137.

Widom

C. S.

(1978). An empirical classification of female offenders. Criminal Justice and Behavior 5, 35–52.

138.

Winston

J. S.

O'Doherty

Dolan

R. J.

(2003). Common and distinct neural responses during direct and incidental processing of multiple facial emotions. Neuroimage 20, 84–97.

139.

Winston

J. S.

Strange

B. A.

O'Doherty

Dolan

R. J.

(2002). Automatic and intentional brain responses during evaluation of trustworthiness of faces. Nature Neuroscience 5, 277–283.