Session 1: Metastasis

Kim, J.W. , et al. (2004). Cancer-associated molecular signatures in the cirrhotic tissue samples of patients with chronic liver disease. Hepatology 39, 518—27.

Ye, Q.H. , et al. (2003). Predicting hepatitis B virus-positive metastatic hepatocellular carcinomas using gene expression profiling and supervised machine learning. Nat Med 9, 416—23.

Iizuka, N. , et al. (2003). Oligonucleotide microarray for prediction of early intrahepatic recurrence of hepatocellular carcinoma after curative resection. Lancet 361, 923—29.

Ramaswamy, S. , et al. (2003). A molecular signature of metastasis in primary solid tumors. Nat Genet 33, 49—54.

Ramaswamy, S. , Tamayo, P. , Rifkin, R. , Mukherjee, S. , Yeang, C.H. , Angelo, M. , Ladd, C. , Reich, M. , Latulippe, E. , Mesirov, J.P. , Poggio, T. , Gerald, W. , Loda, M. , Lander, E.S. , and Golub, T.R. (2001). Multi-class cancer diagnosis using tumor gene expression signatures. Proc Natl Acad Sci 98, 15149—54.

Ramaswamy, S. , Ross, K.N. , Lander, E.S. , and Golub, T.R. (2003). A molecular signature of metastasis in primary solid tumors. Nature Genetics 33, 49—54.

Ramaswamy, S. , and Perou, C.M. (2003). DNA microarrays in cancer: Realising the promise of personalised medicine. Lancet 361, 1576—7.

Lamb, J. , Ramaswamy, S. , Forde, H.L. , Contreras, B. , Martinez, R.V. , Kittrell, F.S. , Zahnow, C.A. , Patterson, N. , Golub, T.R. , and Ewen, M.E. (2003). A mechanism of cyclin D1 action encoded in patterns of gene expression in human cancer. Cell 114, 323—34.

Ramaswamy, S. (2004). Perspective: Translating cancer genomics into clinical oncology. New Engl J Med 350, 1814—6.

Yang, J. , Mani, S.A. , Donaher, J.L. , Ramaswamy, S. , Itzykson, R.A. , Come, C. , Savagner, P. , Gitelman, I. , Richardson, A. , and Weinberg, R. (2004). An essential role of the transcription factor Twist in tumor metastasis. Cell 117, 927—39.

Fidler, I.J. , and Radinsky, R. (1990). Genetic control of cancer metastasis. JNCI 82, 166—8.

Fidler, I.J. , and Radinsky, R. (1996). Search for genes that suppress cancer metastasis. JNCI 88, 1700—3.

Liotta, L.A. , and Kohn, E.C. (2003). Cancer's deadly signature . Nature Genetics 33, 10—1.

Radinsky, R. (1995). Modulation of tumor cell gene expression and phenotype by the organ-specific metastatic environment . Cancer Met Rev 14, 323—38.

Ramaswamy, S. (2004). Translating cancer genomics into clinical oncology. N Engl J Med 350, 1814—6.

Ye, Q.-H. , Qin, L.-X. , Forgues, M. , He, P. , Kim, J.W. , Peng, A.C. , Simon, R. , Li, Y. , Robles, A.I. , Chen, Y. , Ma, Z.-C. , Wu, Z.-Q. , Ye, S.-L. , Liu, Y.-K. , Tang, Z.-Y. , and Wang, X.-W. (2003). Predicting hepatitis B virus-positive metastatic hepatocellular carcinomas using gene expression profiling and supervised ma chine learning. Nat Med 9, 416—23.

Kang, Y. , Siegel, P.M. , Shu, W. , Drobnjak, M. , Kakonen, S.M. , Cordon-Cardo, C. , Guise, T.A. , and Massague, J. (2003). A multigenic program mediating breast cancer metastasis to bone. Cancer Cell 3, 537—49.

van't Veer, L.J. , Dai, H. , van de Vijver, M.J. , He, Y.D. , Hart, A.A.M. , Mao, M. , Peterse, H.L. , van der Kooy , K. , Marton, M.J. , Witteveen, A.T. , Schreiber, G.J. , Kerkhoven, R.M. , Roberts, C. , Linsley, P.S. , Bernards, R. , and Friend, S.H. (2002). Gene expression profiling predicts clinical outcome of breast cancer. Nature 415, 530—6.

Ramaswamy, S. , Ross, K.N. , Lander, E.S. , and Golub, T.R. (2003). A molecular signature of metastasis in primary solid tumors. Nature Genetics 33, 49—54.

Huang, E. , Cheng, S.H. , Dressman, H. , Pittman, J. , Tsou, M.H. , Horng, C.F. , Bild, A. , Iversen, E.S. , Liao, M. , Chen, C.M. , West, M. , Nevins, J.R. , and Huang, A.T. (2003). Gene expression predictors of breast cancer outcomes . Lancet 361, 1590—6.

Bernards, R. , and Weinberg, R.A. (2002). A progression puzzle . Nature 418, 823.

Cattley, R.C. , and Radinsky, R. (2004). Cancer therapeutics: Understanding the mechanism of action. Toxicol Pathol 32(Suppl 1), 116—21.

Ramaswamy, S. , Tamayo, P. , Rifkin, R. , Mukherjee, S. , Yeang, C. -H., Angelo, M. , Ladd, C. , Reich, M. , Latulippe, E. , Mesirov, J.P. , Poggio, T. , Gerald, W. , Loda, M. , Lander, E.S. , and Golub, T.R. (2001). Multiclass cancer diagnosis using tumor gene expression signatures. Proc Natl Acad Sci 98, 15149—54.

Rhodes, D.R. , Yu, J. , Shanker, K. , Deshpande, N. , Varambally, R. , Ghosh, D. , Barrette, T. , Pandey, A. , and Chinnaiyan , A.M. (2004). Large-scale meta-analysis of cancer microarray data identifies common transcriptional profiles of neoplastic transformation and progression. Proc Natl Acad Sci 101, 9309—14.