This paper presents the first analysis of scientific strength by output (papers in the Science Citation Index 1994-96) produced by authors from the 'greater' urban regions of Europe. Top lists of European centres are indicated. Four agglomerations constitute the European super-league of science: London, Paris, Moscow and the Dutch urban agglomeration of Amsterdam, the Hague, Rotterdam and Utrecht. The next layer could be named the primary league and comprises 19 large research centres. A third group of 16 cities forms a secondary league of 16 smaller research centres. These upper-level research strongholds are categorised in the paper where patterns of specialisations by absolute and relative distribution of research disciplines for each city are identified and families of cities by research pattern are analysed and compared within the perspective of urban economic growth and change.
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