We investigate conceptually the institutional change process and innovation underpinning knowledge-based regional development from the point of view of institutional entrepreneurship. The main aim is to raise institutional entrepreneurship among debated concepts in regional development studies. We set out to discuss the following question: what kind of conceptual base provides empirical studies with a fresh set of research questions and hence point of departure in a study of the ways in which actors influence the course of events and aim to change the very institutional setting in which they are embedded?
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