Otogenic Meningitis Caused by the Pneumococci that had Acquired Resistance to Cephalosporins

1 House HP. Otitis media: Comparative study of results obtained in therapy before and after introduction of sulfomomide compounds. Arch Otolaryngol 1946; 43:371–8.

2 Hofmann J Cetron MS Farley MM , et al. The prevalence of drug-resistant Streptococcus pneumoniae in Atlanta. N Engl J Med 1995; 333:481–6.

3 Appenbaum PC. Antimicrobial resistance in streptococcus pneumoniae: An overview. Clin Infect Dis 1992; 15:77–83.

4 Markiewicz Z Tomsz A. Variation in penicillin-binding protein patterns of penicillin-resistant clinical isolates of pneumococci. J Clin Microbiol 1989; 27:405–10.

5 Coffey TJ Daniels M McDougal LK , et al. Genetic analysis of clinical isolates of streptococcus pneumoniae with high-level resistance to expanded-spectrum cephalosporins. Antimicrob Agents Chemother 1995; 39:1306–13.