Cardiac indications for the use of mechanical cardiopulmo nary support techniques in infants and children include short-term circulatory support during reversible myocardial failure, cardiopulmonary support before and after cardiac surgery, and a bridge to cardiac transplantation. For practi cal purposes, 3 modalities are currently available for these patients: extracorporeal membrane oxygenation, use of ven tricular assist devices, and intra-aortic balloon pump coun terpulsation. Although a variety of devices are available for larger patients, the need for smaller sizes and a wider range of sizes has delayed their use in children. This article sum marizes the current systems available for children as well as indications and outcome data related to their use in infants and children with congenital or acquired heart disease. Copyright © 2001 by W.B. Saunders Company.