Abstract
Delayed hypersensitivity to rubber chemicals in the standard test series is not uncommon. Many people are exposed daily to various rubber objects, but it is usually difficult to discover whether a particular object contains the rubber sensitizer under discussion. Therefore, the assessment of clinical relevance is generally based on the result of patch testing with rubber objects as they are. However, this patch testing may be negative, although the exposure to a rubber object is responsible for the dermatitis. This article describes a patch test procedure with extracts of rubber objects or objects based on other materials obtained from ultrasonic baths. Examples will be given of clinically relevant exposure to such objects in which only testing with the extracts yielded positive patch test results.
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