OBJECTIVE: The purposes of this study were to examine milk allergic patients to determine concomitant reactivity between milk, beef, pork and cat and dog dander and other common inhalant allergens.
METHODS: 19 patients were selected according to their Immuno-CAP results, which had increased Ig-E levels against milk, pork or beef. Patients were also tested against Johnson grass, short ragweed, cat/dog dander and d. farina.
RESULTS: Pearson's test revealed strong correlation between beef and pork, beef and milk, pork and milk Ig-E counts (consecutively r2 = 0.89, r2 = 0.81, r2 = 0.60 and p < 0.01. All cat allergic patients also appeared to be allergic to either beef/pork meat or milk. The correlation between pork and dog dander Ig-E counts was also significant (r2 = 0.38, p < 0.01). No correlation detected between milk-meat-pet and grass-weed-dust allergies.
DISCUSSION AND CONCLUSION: Patients who are known to have pet allergies may need to be screened for meat and milk allergy. Milk allergic patients may also need to avoid cows and pork meat.
Get full access to this article
View all access options for this article.
References
1.
EigenmannPA. Anaphylaxis to cow's milk and beef meat proteins. Ann Allergy Asthma Immunol2002; 89(6 Suppl 1):61–4.
2.
PesslerFNejatM.Anaphylactic reaction to goat's milk in a cow's milk-allergic infant. Pediatr Allergy Immunol2004; 15: 183–5.
3.
ViethsSScheurerSBallmer-WeberB.Current understanding of cross-reactivity of food allergens and pollen. Ann N Y Acad Sci2002; 964: 47–68.
4.
CadotPKochuytAMvan ReeROral allergy syndrome to chicory associated with birch pollen allergy. Int Arch Allergy Immunol2003; 131: 19–24.
5.
PajnoGBMorabitoLBarberioG.Allergy to house dust mite and snails: A model of cross-reaction between food and inhalant allergens with a clinical impact. Pediatr Pulmonol Suppl1999; 18: 163–4.
6.
GanglbergerERadauerCWagnerSHev b 8, the Hevea brasiliensis latex profilin, is a cross-reactive allergen of latex, plant foods and pollen. Int Arch Allergy Immunol2001; 125: 216–27.
7.
Gavrovic-JankulovicMCirkovicTBurazerLIgE cross-reactivity between meadow fescue pollen and kiwi fruit in patients' sera with sensitivity to both extracts. J Investig Allergol Clin Immunol2002; 12: 279–86.
DrouetMSabbahA.The pork/cat syndrome or crossed reactivity between cat epithelia and pork meat. Monogr Allergy1996; 32: 164–73.
10.
HilgerCKohnenMGrigioniFAllergic cross-reactions between cat and pig serum albumin. Studies at the protein and DNA level. Allergy1997; 52: 179–87.
11.
PaschkeABeslerM.Stability of bovine allergens during food processing. Ann Allergy Asthma Immunol2002; 89(6 Suppl 1):16–20.
12.
FiocchiARestaniPRivaEStability of bovine allergens during food processing. Ann Allergy Asthma Immunol2002; 89(6 Suppl 1):16–20.
13.
BockSASampsonHAAtkinsFMDouble-blind, placebo-controlled food challenge (DBPCFC) as an office procedure; a manual. J Allergy Clin Immunol1988; 82: 986–97.
14.
MartelliADe ChiaraACorvoMBeef allergy in children with cow's milk allergy; cow's milk allergy in children with beef allergy. Ann Allergy Asthma Immunol2002; 89(6 Suppl 1):38–43.
