Nuchal Translucency and First-Trimester Screening

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References

1. Orlandi F , Damiani G , Hallahan TW , Krantz DA , Macri JN . First-trimester screening for fetal aneuploidy: biochemistry and muchal translucency. Ultrasound Obstet Gynecol 1997;10:381-386.

2. De Biasio P , Siccardi M , Volpe G , Famularo L , Santi F , Canini S . First-trimester screening for Down syndrome using nuchal translucency measurement with free beta-hCG and PAPP-A between 10 and 13 weeks of pregnancy—the combined test. Prenat Diagn 1999;19:360-363.

3. Egan JF , Kaminsky LM , DeRoche ME , Barsoom MJ , Borgida AF , Benn PA . Antenatal Down syndrome screening in the United States in 2001: a survey survey of maternal-fetal medicine specialists. Am J Obstet Gynecol 2002;187:1230-1234.

4. Haak MC , van Vugt JM . Pathophysiology of increased nuchal translucency: a review of the literature. Hum Reprod Update 2003;9:175-184.

5. Nicolaides KH , Azar G , Byrne D , Mansur C , Marks K . Fetal nuchal translucency: ultrasound screening for chromosomal defects in first trimester of pregnancy. Br Med J 1992;304:867-869.

6. Wald NJ , Rodeck C , Hackshaw AK , Walters J , Chitty L , Mackinson AM . First and second trimester antenatal screening for Down's syndrome: the results of the Serum, Urine, and Ultrasound Screening Study (SURUSS). J Med Screen 2003;10:56-104.

7. Malone FD , Canick JA , Ball RH , et al. First-trimester or second-trimester screening, or both, for Down's for Down's syndrome. N Engl J Med 2005;353:2001-2011.

8. Wapner R , Thom E , Simpson JL , et al. First-trimester screening for trisomies 21 and 18. N Engl J Med 2003;349:1405-1413.

9. Lau TK , Leung TN . Genetic screening and diagnosis. Curr Opin Obstet Gynecol 2005;17:163-169.