This study sought to examine the association between the type and intensity of exercise as a lifestyle habit with sex steroid hormones, sexual activities, sleep parameters and aging in men.
Methods:
Exercise scores, sleep duration and sexual activities were evaluated through a self-administered questionnaire, while testosterone (T), sex hormone binding globulin (SHBG), estradiol (E2) and dehydroepiandrosterone sulfate (DHEAS) levels were measured using established immunoassay methods. Bioavailable T was calculated using Vermeulen's formula.
Results:
Moderately intense exercise as a lifestyle habit was significantly associated with higher coital frequency, higher sex hormone concentrations, and more men engaging in masturbation, but fewer men having problems falling asleep. While increasing the intensity of exercise did not alter the beneficial effects noted with moderately intense exercise on sex hormones, masturbation and falling asleep, it was significantly associated with decreased coital frequency.
Conclusion:
This study showed that moderately intense exercise as a lifestyle habit was associated with better sexual function, better ability to fall asleep and higher concentrations of sex hormones. These findings support the importance of promoting a lifestyle habit of exercise to mitigate the increased risks of having sexual and sleep dysfunctions as men age.
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References
1.
GohV.H.H., TongT.Y.Y., MokH.P.P., SaidB.Interactions among age, adiposity, bodyweight, lifestyle factors and sex steroid hormones in healthy Singaporean Chinese men. Asian J Androl, 2007; 9:611–621.
2.
VermeulenA.Clinical review 24: androgens in the aging male. J Clin Endocrinol Metab, 1991; 73(2):221–224.
3.
FeldmanH.A., LongcopeC., DerbyC.A., JohannesC.B., AraujoA.B., CoviellaA.D., et al.Age trends in the level of serum testosterone and other hormones in middle-aged men: longitudinal results from the Massachusetts male aging study. J Clin Endocrinol Metab, 2002; 87(2):589–598.
4.
ZmudaJ.M., CauleyJ.A., KriskaA., GlynnN.W., GutaiJ.P., KullerL.H.Longitudinal relation between endogenous testosterone and cardiovascular disease risk factors in middle-aged men. A 13-year follow-up of former Multiple Risk Factor Intervention Trial participants. Am J Epidemiol, 1997; 146(8):609–617.
5.
DavidsonJ.M., ChenJ.J., CrapoL., GrayG.D., GreenleafW.J., CataniaJ.A.Hormonal changes and sexual function in aging men. J Clin Endocrinol Metab, 1983; 57(1):71–77.
6.
HijaziR.A., CunninghamG.R.Andropause: is androgen replacement therapy indicated for the aging male?. Annu Rev Med, 2005; 56:117–137.
7.
KaufmanJ.M., VermeulenA.The decline of androgen levels in elderly men and its clinical and therapeutic implications. Endocr Rev, 2005; 26(6):833–876.
8.
HakA.E., WittemanJ.C., de JongF.H., GeerlingsM.I., HofmanA., PolsH.A.Low levels of endogenous androgens increase the risk of atherosclerosis in elderly men: the Rotterdam study. J Clin Endocrinol Metab, 2002; 87(8):3632–3639.
9.
StampferM., HuF., MansonJ., RimmE., WillettW.Primary prevention of coronary heart disease in women through diet and lifestyle. N Engl J Med, 2000; 343(1):16–23.
10.
HuF.B., MansonJ.E., StampferM.J., ColditzG., LiuS., SolomonC.G., et al.Diet, lifestyle, and the risk of type 2 diabetes mellitus in women. N Engl J Med, 2001; 345(11):790–797.
11.
O’ConnorD., CroweM., SpinksW.Effects of static stretching on leg power during cycling. Turin, 2006; 46(1):52–56.
12.
de VosN.J., SinghN.A., RossD.A., StavrinosT.M., OrrR., Fiatarone SinghM.A.Optimal load for increasing muscle power during explosive resistance training in older adults. J Gerontol A Biol Sci Med Sci, 2005; 60(5):638–647.
13.
GruenewaldD.A., MatsumotoA.M.Testosterone supplementation therapy for older men: potential benefits and risks. J Am Geriatr Soc, 2003; 51(1):101–115.
14.
BonifaziM., BelaE., CarliG., LodiL., MartelliG., ZhuB., et al.Influence of training on the response of androgen plasma concentrations to exercise in swimmers. Eur J Appl Physiol Occup Physiol, 1995; 70(2):109–114.
15.
FellmannN., CoudertJ., JarrigeJ.F., BeduM., DenisC., BoucherD., et al.Effects of endurance training on the androgenic response to exercise in man. Int J Sports Med, 1985; 6(4):215–219.
16.
HackneyA.C., FahrnerC.L., GulledgeT.P.Basal reproductive hormonal profiles are altered in endurance trained men. J Sports Med Phys Fitness, 1998; 38(2):138–141.
17.
HackneyA.C., PremoM.C., McMurrayR.G.Influence of aerobic versus anaerobic exercise on the relationship between reproductive hormones in men. J Sports Sci, 1995; 13(4):305–311.
18.
KraemerW.J., HakkinenK., NewtonR.U., McCormickM., NindlB.C., VolekJ.S., et al.Acute hormonal responses to heavy resistance exercise in younger and older men. Eur J Appl Physiol Occup Physiol, 1998; 77(3):206-1 1.
19.
WilloughbyD.S., TaylorL.Effects of sequential bouts of resistance exercise on androgen receptor expression. Med Sci Sports Exerc, 2004; 36(9):1499–1506.
20.
HerbstK.L., BhasinS.Testosterone action on skeletal muscle. Curr Opin Clin Nutr Metab Care, 2004; 7(3):271–277.
21.
KraemerW.J., RatamessN.A.Hormonal responses and adaptations to resistance exercise and training. Sports Med, 2005; 35(4):339–361.
22.
AriZ., KutluN., UyanikB.S., TaneliF., BuyukyaziG., TavliT.Serum testosterone, growth hormone, and insulin-like growth factor-1 levels, mental reaction time, and maximal aerobic exercise in sedentary and long-term physically trained elderly males. Int J Neurosci, 2004; 114(5):623–637.
23.
MullerM., den TonkelaarI., ThijssenJ.H., GrobbeeD.E., van der SchouwY.T.Endogenous sex hormones in men aged 40-80 years. Eur J Endocrinol, 2003; 149(6):583–589.
24.
SallinenJ., HoglundI., EngstromM., LehtimakiJ., VirtanenR., SirvioJ., et al.Pharmacological characterization and CNS effects of a novel highly selective alpha2C-adrenoceptor antagonist JP-1302. Br J Pharmacol, 2007; 150(4):391–402.
25.
IzquierdoM., HakkinenK., IbanezJ., GarruesM., AntonA., ZunigaA., et al.Effects of strength training on muscle power and serum hormones in middle-aged and older men. J Appl Physiol, 2001; 90(4):1497–1507.
26.
NicklasB.J., RyanA.J., TreuthM.M., HarmanS.M., BlackmanM.R., HurleyB.F., et al.Testosterone, growth hormone and IGF-I responses to acute and chronic resistive exercise in men aged 55-70 years. Int J Sports Med, 1995; 16(7):445–450.
27.
TymchukC.N., TesslerS.B., AronsonW.J., BarnardR.J.Effects of diet and exercise on insulin, sex hormone-binding globulin, and prostate-specific antigen. Nutr Cancer, 1998; 31(2):127–131.
28.
SufiS, DonalsonA, JeffcoateSL. Method Manual. WHO Special Programme of Research, Development and Research Training in Human Reproduction. Programme for the Provision of Matched Assay Reagents for the Radioimmunoassay of Hormones in Reproductive Physiology. Geneva: WHO; 1992.
29.
GohH.H., ChowA., WangF.L., RatnamS.S.Comparisons of a tritium labeled-based classical radioimmunoassay with a newly developed scintillation proximity assay for measurement of plasma oestradiol-17-beta. J Med Lab Sci, 1990;(1):33–35.
30.
GohH.H., KarimS.M.M., ChewP.C.T., RatnamS.S.Peripheral conversion of testosterone to oestradiol in male transsexuals after sex reassignment. Singapore J Obstet Gynecol, 1978; 9(3):85–90.
31.
ChiaS.E., GohV.H.H., OngC.N.Endocrine profiles of male workers with exposure to trichloroethylene. Am J Industr Med, 1997; 32:217–222.
32.
VermeulenA., VerdonckL., KaufmanJ.M.A critical evaluation of simple methods for the estimation of free testosterone in serum. J Clin Endocrinol Metab, 1999; 84(10):3666–3672.
33.
JakicicJ.M., MarcusB.H., GallagherK.I., NapolitanoM., LangW.Effect of exercise duration and intensity on weight loss in overweight, sedentary women: a randomized trial. JAMA, 2003; 290(10):1323–1330.
34.
HaskellW.L., LeeI.M., PateR.R., PowellK.E., BlairS.N., FranklinB.A., et al.Physical activity and public health: updated recommendation for adults from the American College of Sports Medicine and the American Heart Association. Med Sci Sports Exerc, 2007; 39(8):1423–1434.
35.
PatersonD.H., JonesG.R., RiceC.L.Ageing and physical activity: evidence to develop exercise recommendations for older adults. Can J Public Health, 2007; 98(Suppl 2):S69–108.
36.
EspositoK., CiotolaM., GiuglianoF., MaiorinoM.I., AutorinoR., De SioM., et al.Effects of intensive lifestyle changes on erectile dysfunction in men. J Sex Med, 2009; 6(1):243–250.
37.
WhiteJ.R., CaseD.A., McWhirterD., MattisonA.M.Enhanced sexual behavior in exercising men. Arch Sex Behav, 1990; 19(3):193–209.
38.
HutchinsonK.A.Androgens and sexuality. Am J Med, 1995; 98(1A):111S–115S.
39.
DavidsonJ.M., ChenJ.J., CrapoL., GrayG.D., GreenleafW.J., CataniaJ.A.Hormonal changes and sexual function in aging men. J Clin Endocrinol Metab., 1983; 57(1):71–77.
40.
GrandysM., MajerczakJ., DudaK., Zapart-BukowskaJ., KulpaJ., ZoladzJ.A.Endurance training of moderate intensity increases testosterone concentration in young, healthy men. Int J Sports Med, 2009 Mar 19[Epub ahead of print].
41.
BonifaziM., BelaE., CarliG., LodiL., MartelliG., ZhuB., et al.Influence of training on the response of androgen plasma concentrations to exercise in swimmers. Eur J Appl Physiol Occup Physiol, 1995; 70(2):109–114.
42.
KraemerW.J., GordonS.E., FleckS.J., MarchitelliL.J., MelloR., DziadosJ.E., et al.Endogenous anabolic hormonal and growth factor responses to heavy resistance exercise in males and females. Int J Sports Med, 1991; 12(2):228–235.
43.
KraemerW.J., PattonJ.F., KnuttgenH.G., MarchitelliL.J., CruthirdsC., DamokoshA., et al.Hypothalamic–pituitary–adrenal responses to short-duration high-intensity cycle exercise. J Appl Physiol, 1989; 66(1):161–166.
44.
HakkinenK., PakarinenA.Acute hormonal responses to two different fatiguing heavy-resistance protocols in male athletes. J Appl Physiol, 1993; 74(2):882–887.
45.
HawkinsV.N., Foster-SchubertK., ChubakJ., SorensenB., UlrichC.M., StancyzkF.Z., et al.Effect of exercise on serum sex hormones in men: a 12-month randomized clinical trial. Med Sci Sports Exerc, 2008; 40(2):223–233.
46.
KraemerW.J., HäkkinenK., NewtonR.U., NindlB.C., VolekJ.S., McCormickM., et al.Effects of heavy-resistance training on hormonal response patterns in younger vs. older men. J Appl Physiol, 1999; 87(3):982–992.
47.
BoudouP., de KervilerD., ErlichD., VexiauP., GautierJ.-F.Exercise training-induced triglyceride lowering negatively correlates with DHEA levels in men with type 2 diabetes. Int J Obesity, 2001; 25(8):1108–1112.
48.
BliwiseD.L., KingA.C., HarrisR.B., HaskellW.L.Prevalence of self-reported poor sleep in a healthy population aged 50-65. Soc Sci Med, 1992; 34(1):49–55.
49.
HarrisonY., HorneJ.A.Should we be taking more sleep?. Sleep, 1995; 18(10):901–907.
50.
SteinR.Scientists finding out what losing sleep does to a body. The Washington Post, 2005; October9; sect A:01.
51.
OpstadP.K.Androgenic hormones during prolonged physical stress, sleep and energy deficiency. J Clin Endocrinol Metab, 1992; 74(5):1176–1183.
52.
RemesK., KuoppasalmiK., AdlercreutzH.Effect of physical exercise and sleep deprivation on plasma androgen levels: modifying effect of physical fitness. Int J Sports Med, 1985; 6(3):131–135.
