Abstract
With aging in most but not all men
• Total testosterone levels decline • Even more so free testosterone levels • This is associated with symptoms of testosterone deficiency, not only of sexual functioning but also of bone density, muscle mass and metabolic risk factor for cardiovascular disease and diabetes • The diagnosis is based both on clinical symptoms and on laboratory measurements, more so of free testosterone than of total testosterone. • Treatment with testosterone is acceptably safe provided established guidelines are adhered to
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