Abstract
Aalborg
Paddle Wheel Flow Meters
These new Paddle Wheel Flow Meters are designed for measuring very low liquid flow rates and for highly accurate temperature readings, considered easy to install and operate, feature one moving part, and their sapphire jewel bearings facilitate virtually friction-free impeller wheel rotations that result in linear low flow metering. Models constructed of polypropylene or chemically resistant PVDF can be mounted either horizontally or vertically.
More: www.aalborg.com
Direct Reading Scales for Models P, S, and T Flow Meters
Direct reading flow tube scales are designed exclusively for a specific gas or liquid (including argon, carbon dioxide, helium, hydrogen, hydrogen chloride, methane, nitrous oxide, oxygen, and propane) at a given temperature and pressure valid only for the associated units of flow. Easy-to-read flow rates for a specified set of parameters are clearly indicated in specific engineering units, such as mL/min or scfh.
More: www.aalborg.com
Accelerated Technology Laboratories
Bulldog LIMS
According to Accelerated Technology Laboratories, its new ATL Bulldog is a next-generation laboratory informatics platform that delivers a world-class laboratory information management systems (LIMSs). Key features include user-friendly design, ease of administration and configuration, state management, integrated report designer or external tools, enterprise integration, security, and a remote access browser.
The new ATL Bulldog is a modern development environment that is built on Microsoft Visual Studio 2008 and Microsoft. NET 3.5. The ATL Bulldog Framework is a highly configurable SOA solution built upon the Microsoft Windows Communication Foundation, which provides the ability to configure business rules to match organizational requirements.
A powerful workflow management system allows users to graphically define, manage, and execute tasks and even provides a model to develop additional workflow activities. Workflows can be used to manipulate data, dispatch notifications, generate and send reports and other files via fax and e-mail, as well as evaluate complex logic that reflects real-world processes and decisions. This new platform uses the Microsoft ClickOnce deployment technology for easy installation and upgrading.
Sample Master LIMS 8.5
Sample Master LIMS 8.5 offers new functionality that includes workload management for both instruments and analysts into the Resource Management module; wildcard support on the Master Query; additional sample fields in the Master Query; standards management in Chemical Inventory module; QC batch tracking of standards; automatic notifications on results using user-created criteria such as over/under limits, calculations, etc.; enhanced fax/e-mail configurations; enhanced QC batching including batching by analysis method; ability to reprint multiple samples and multiple orders; modified PDF report naming for auto reporting; due dates for orders and reports; sortable custom report listing; and enhanced information for samples, instruments, contacts, results, laboratory, etc.
More: www.atlab.com
Accuri Cytometers
C6 Flow Cytometer
According to Accuri, its new C6 Flow Cytometer, now
available in Europe, features 2 Lasers, 6 detectors, measures 2 ft2 (0.19 m2) in size, delivers performance similar to market leaders, has an optional CSampler for multiwell plate automation, and is considered easy to set up and operate.
More: www.accuricytometers.com
Air Science
PURAIR-VLF Laminar Flow Workstation
Air Science's new PURAIR-VLF is a ready-to-use, compact, bench-mounted workstation that provides clean air conditions comparably better than Class 100 at the work surface. It is fitted with an electronic monitoring alarm to signal when airflow falls to an unacceptable level. In addition to standard internal fluorescent work surface lighting, the cabinet has an integrated UV sterilizer that can destroy contamination. Users are protected by an interlocked front door that prevents accidental exposure to the UV rays.
More: www.air-science.com
ARTEL
MVS Multichannel Verification System
Artel has developed functionality for its MVS Multichannel Verification System to verify volumes of glycerol, ethanol, and DMSO transferred from an automated liquid-handling system or a handheld pipette to a microtiter plate.
More: www.artel-usa.com
Astech Projects
Xelair Series 5 Automated Inhaler Tester
According to Astech, its new fully automated Xelair Series 5 system for automated inhaler testing incorporates all existing features of the Xelair 1 and 3 series, plus a Device Handling and Storage module with optional waste fire for automated storage, handling, and transfer of all devices. In addition, the Xelair Series 5 system offers an increased capacity for emitted dose collection, and the ability to test up to 200 inhalers per day.
More: www.astechprojects.com
Beckman Coulter
PA 800 Plus Pharmaceutical Analysis System
According to Beckman Coulter, its new PA 800 plus Pharmaceutical Analysis System is a next-generation capillary electrophoresis platform designed in collaboration with biopharmaceutical development and QC groups to provide a robust and easy-to-use characterization platform that integrates quantitative, qualitative, and automated solutions for analysis of protein purity, charge isoform distribution, and glycan structure. An emphasis on the portability of assays between laboratories enhances system utility in multiuser/multi-instrument facilities. Modular ultraviolet, photodiode array, and solid-state, laser-induced fluorescence detectors are readily interchanged for a variety of applications.
More: www.celeader.com
Biochrom
SD Card Accessory for WPA Spectrophotometers
The SD card accessory enables data to be exported from Biochrom's WPA advanced life science spectrophotometers to a PC using standard SD or SDHC memory cards. It can be easily fitted to the Biowave DNA, Lightwave II, and Biowave II instruments and comes complete with user-friendly Print Via Computer software. Storing methods on a memory card allows users to save and backup their methods and is considered particularly useful to users running multiple instruments, allowing them to transfer settings and clone methods. The new SD card accessory complements existing options to export data via a USB connection, or make use of the integrated printer or wireless Bluetooth accessories.
More: www.biochrom.co.uk or www.biochrom-us.com
Biohit
Filter Tips
According to Biohit, the higher filter positioning in these new models prevents the liquid sample from touching the filter, enabling safer pipetting in reverse and multidispensing modes.
These tips cover the volume range from 0.1 to 1200 μL including new sizes for 10-, 20-, 100/120-, 200-, 300-, 1000-, and 1200-μL volume capacities, and offer optimal tip compatibility with Biohit Pipettes. They are packed in color-coded single tray boxes, wrapped in airtight plastic, and electron beam sterilized with the tip size ID printed on the sterilization indicator. The tips are made of virgin polypropylene and the filters are polyethylene.
More: http://www.us.biohit.com or www.biohit.com
BioTek Instruments
Gen5 Data Analysis Software
For BioTek's microplate detection instruments, Gen5 Microplate Data Analysis Software version 1.08.4 provides new features to enhance enterprise-wide user management and system notifications.
Gen5 Secure and Gen5CL now offer a Windows Authentication (Single Sign On) option to allow users to access Gen5 without having to login. This feature allows more efficiency in the administration and authentication of user credentials while reducing potential password fatigue among users.
Also featured is the ability to have Gen5 alert designated users to certain events during routine use. For example, a user can be notified when the plate reading process run is completed, or when data have successfully been exported, among other events. The customizable e-mail notification option is available in Gen5 Secure and Gen5CL. Gen5 v 1.08.4 also expands the data sets that can be defined in an export table or matrix to include system or user-generated data objects.
More: www.biotek.com
Synergy Mx
According to BioTek, its new modular Synergy Mx Multimode Microplate Reader with Ultra Fine-Tuned performance provides fluorescence, luminescence and absorbance results on par with that normally found only in dedicated single-mode systems. The top- and bottom-read fluorescence system is fully monochromator based and equipped with a variable bandpass selection system for added flexibility, whereas premium quadruple grating architecture guarantees spectral discrimination and smooth spectral scans.
More: www.biotek.com
CEVEC Pharmaceuticals
CAP-T Transient Expression System
According to CEVEC, its new CAP-T transient expression system for fast, serum free, and high-yield protein production enables users to proceed from gene to milligram and gram amounts of protein within only 2 weeks. In addition, authentic human post-translational modifications especially with complex and highly glycosylated proteins make it an ideal tool for screening, assay development, target validation, drug discovery, early stage preclinical drug development, and lead optimization. CAP-T cells are based on CAP cells and match all their positive features with regard to comprehensive documentation, safety, nontumor origin, and growth as suspension culture in serum- and protein-free media optimized for industrial use. CAP-T is available under flexible research license arrangements.
ChemSW
CISPro Biological Materials Module
CISPro Biological Materials Module in ChemSW's CISPro Global and CISPro Live chemical inventory systems delivers enhanced functionality for tracking biological materials in inventory. Along with standard criteria such as location or species, the module can track containers of reagents, bacteria, or purified plasma in even greater detail through user-defined fields that suit particular work processes.
More: www.chemsw.com/bio.htm
Clinical and Laboratory Standards Institute
Infobase 2009
Infobase 2009 is a user-friendly searchable CD-ROM that includes the CLSI library of clinical and laboratory standards and guidelines for medical testing best practices, and all approved- and proposed-level documents published through December 31, 2008, as well as archived documents.
More: www.clsi.org
Copley Controls
EtherCAT Connectivity for Accelnet
According to Copley, it has leveraged FPGA technology to implement a cost-effective EtherCAT interface and expand motor feedback and input/output options for the Accelnet servo drive. Encoder interfaces include EnDat, Hiperface, and BiSS.
Available in six current ratings, the compact Accelnet drives a wide range of brushless and brush motors. Several DC supply options are available in the 20 ∼ 180 V range. The drives are panel mounted and fully connectorized. As well as operating as an EtherCAT slave, the drive incorporates a range of control modes including camming, gearing, and a fully programmable indexer. Copley supports Accelnet with comprehensive software tools that capitalize on the CANopen device profile of EtherCAT.
More: www.copleycontrols.com
Bantam Analog Amplifier Module
The new Bantam analog amplifier module for torque control of brushless and brush motors is available in two current ratings. The 500 W Bantam has a tiny footprint of only 3.8 in.2, and is PCB mounted with solderless connectors. The amplifier accepts a standard ±10 V current command from an external controller. Other analog control inputs are available to set current limits and adjust balance. Digital I/O includes overtravel limits, HI/LO motor inductance range selection, amplifier status, and brake control. A digital Hall interface is provided for trapezoidal commutation of brushless motors.
More: www.copleycontrols.com
CyBio
CyBi-WellFlex and CyBi-WellFlex Vario Multipipetting Head
CyBi-WellFlex and CyBi-WellFlex vario now form a combination of a multipipetting head, an eight-channel and a one-channel pipetting tool, and an optional dispenser for the automation of liquid-handling applications. The combination of the eight- and one-channel pipetting tool on one pipetting head is constantly available without replacement, allowing full automation from creation of the master mix up to the simultaneous processing of a large number of sample; and allowing combined processing of standard applications such as the replication or reformatting of complete microplates in the formats 96, 384, and 1536, the execution of dilution series and the hit picking in an integrated platform. For sterile work with cell cultures, the systems can be integrated into standardized flow boxes. The cell dispenser CyBi-Drop can be added without additional lab space.
More: www.cybio-ag.com
Falcon Electric
SVR Pro Series Voltage Regulator and Frequency Converter
According to Falcon, its new SVR Pro Series Solid-State Voltage Regulator (SVR) and Frequency Converter represents one of the industry's first active electronics-based SVRs that fully regenerates new, clean power to ensure equipment uptime at a very affordable cost. Specifically designed to tackle power variances, the SVR Pro 1.5kVA, 2.2kVA, and 3kVA units deliver pure regulated power in a compact and lightweight 31-pound package, and can operate in harsh generator power environments from 0 to 55°C.
With a simple factory modification, SVR units can perform 50-Hz frequency conversion for lab testing and worldwide 230-V applications. With the units' optional battery backup feature, the SVR Pro provides minutes to hours of battery backup power. The SVR removes damaging power pollution and ensures a pure sinewave output with ±2% voltage regulation. These new units feature a wide input voltage window from 80 to 138Vac, as well as a 0.97 input Power Factor Correction circuit that reduces harmonics and the associated wear and tear on a laboratory's wiring system.
FEI Company
Fibermetric Measurement and Analysis System
The new Fibermetric system is powered by the Phenom personal electron microscope, and is designed to discover and quantify the properties of woven and nonwoven fiber samples in minutes, making direct observation and measurement of micro- and nanofibers faster, more accurate, and easier. The system automatically collects hundreds of measurements per image, and generates fiber and pore size distribution plots for quality control and for predicting application properties such as filtration efficiency. The system requires no laboratory infrastructure or specially trained personnel. It has a sample loading time of less than 30 s, and its automated measurement capability generates statistically valid data in the time it takes to load a conventional scanning electron microscope (SEM). Magnifications up to 24,000 times produce accurate information on fibers as small as 100 nm in diameter.
Quanta 50 SEMs
According to FEI, its new Quanta 50 Series of SEMs offers multipurpose design for labs that require high-performance imaging for a broad range of samples, including those that are insulating, wet, dirty, or dynamically changing. Unlike other SEMs, where the sample has to fit the instrument design, the Quanta 50 Series is designed to enable viewing of any sample in its natural state.
Improvements in this new Quanta system are adaptations of some technologies used in FEI's Magellan Extreme High Resolution SEM (XHR SEM), including beam deceleration to increase the surface imaging capability with lower landing energies, and SmartSCAN technologies to further improve image quality by reducing noise.
More: www.fei.com
Fluidigm Europe
EP1 Genetic Analysis System
According to Fluidigm, its new EP1 system for genetic analysis combines the efficiencies of integrated fluidic circuit (IFC)-based genotyping in a desktop-sized configuration. With Fluidigm Dynamic Arrays, the EP1 can deliver better than 99% call rates and 99.75% or greater accuracy, and its easy-to-use, high-throughput workflow can provide up to 9216 data points per IFC chip with results in just 4 h. The EP1 system, which includes the IFC Controller, Stand-Alone Thermal Cycler, and End Point Reader, provides over 27,000 genotypes a day. By adding more IFC controllers and thermal cyclers to be used in conjunction with a single EP1 Reader, more than 200,000 genotypes can be provided in a day. The EP1 system also can perform digital PCR, such as for copy number variation analysis.
More: www.fluidigm.com
SlingShot
Fluidigm's new SlingShot sample quantification system is designed to improve the productivity of next-generation sequencing tools from Roche, Illumina, and Applied Biosystems. It does so by exploiting the unique microfluidic properties of IFCs to detect only amplifiable molecules within the sample mixture.
More: www.fluidigm.com
Fluid Metering
PDS-100 Programmable Dispensing System
According to Fluid Metering, its new PDS-100 is a Programmable Dispensing System uses precision stepper motors to control delivery from 500 nL per dispense up to 2 L per minute continuous flow. It is available in single- and dual-channel configurations.
More: www.fmipump.com
G.E. Healthcare
2-D Electrophoresis Product Suite
According to G.E., its suite of new products improves and simplifies the entire 2-D electrophoresis workflow from sample preparation through to analysis, and further enhances quantitation in protein expression studies. New products include precast low fluorescent DIGE Gels and DIGE Buffer Kit that improve gel-to-gel reproducibility; repackaged CyDye DIGE Fluor saturation and minimal dyes that better suit experimental designs; and reformulated IPG Buffer and IPG strips (Immobiline DryStrip gels) that improve spot resolution. These augment the previously released 2-D Protein Extraction Buffers, IPGbox, and DeCyder 2-D v7 software that contribute to error reduction and optimization of the results in the 2-D experimental workflow.
HiPrep 16/10 Columns
G.E.'s next-generation HiPrep 16/10 columns are redesigned to use significantly less plastic. They are available prepacked with a wide range of chromatography media covering applications for ion exchange chromatography, hydrophobic interaction, and affinity chromatography.
For more information, please visit: www.gelifesciences.com/protein-purification
Greiner Bio-One
CytoCheck DNA Chip
The CytoCheck DNA chip is a ready-to-use test kit that helps identify mycoplasma species in cell cultures and other biological products within a few hours. The test system has been validated by Mycosafe Diagnostics in accordance with the specifications of the European Pharmacopoeia subject to GMP-compliant working conditions. The CytoCheck DNA chip, which is based on high-throughput microArraying technology, is designed for highly sensitive, specific, and reliable mycoplasma detection, with species-specific probes enabling identification of 40 different mycoplasma species. Bacteria are also detected across the board using a universal DNA probe.
More: www.greinerbioone.com
Hamilton Company
DeCapper
The new DeCapper is a programmable automated instrument for opening and closing screw-capped tubes. It can open one row of 12 tubes simultaneously, increasing productivity over one-at-a-time methods and providing more flexibility than systems that decap 96 tubes at once. The DeCapper operates from outside to inside rows to eliminate drip contamination. Built-in torque monitoring ensures a consistent seal and reports the exact location in the event a tube is not completely sealed. After removal, the caps are placed on a separate, removable cap holder to enable batch processing.
The DeCapper can operate as a stand-alone system or be controlled by MicroLab Venus One software for integration with Hamilton Robotics' automated pipetting workstations. It can accommodate manual runs without removal from an integrated workstation. It is also considered an ideal accessory for the Sample Access Manager platforms from Hamilton Storage Technologies.
More: www.hamiltoncompany.com
Hamilton Robotics
MICROLAB STAR Liquid-Handling Workstations
A new 5-mL channel disposable tip is now available for the volume range on the MICROLAB STAR liquid-handling workstations, and according to Hamilton, is the first air-displacement pipetting tool to address the needs of larger sample volume applications. The new channel brings new assay and throughput options to research on blood samples including DNA and RNA extraction and protein biomarker isolation.
More: www.hamiltonrobotics.com
TADM Lab Analyzer
Total Aspiration and Dispense Monitoring (TADM) Lab Analyzer for MICROLAB STAR and STARlet liquid-handling workstations is made possible through a collaboration with Apartis Information Management. According to Hamilton, this new software solution enhances the usability of TADM data from Hamilton STAR workstations by displaying it in graphical, easy-to-interpret formats. TADM Lab Analyzer retrieves and visualizes precise, real-time pressure monitoring data, enabling the user to quickly confirm accurate aspiration and dispense for each sample plate well. The data display also clearly shows deviations from preset guard bands and delivers online warnings. The TADM system can be programmed by users to take specific actions in response to errors.
More: www.hamiltonrobotics.com
Hamilton Storage Technologies
–20 °C SAM
According to Hamilton, its new automated −20 °C Sample Access Manager (SAM) is an affordable cold storage system for compounds and biological samples that ensures sample integrity by maintaining a precise storage environment at user-determined levels, between +20 and −40 °C. Based on the technology behind Hamilton's −80 °C storage system, the −20 °C SAM is a lower throughput, automated system that offers sample format flexibility, cherry picking, sample tracking, and easy-to-use software all within a compact footprint. The system's sample tracking software provides an audit trail and complete chain of custody documentation for regulated environments.
The −20 °C SAM's internal robotics are driven by Hamilton's external magnetic couplers to ensure consistent storage temperature and prevent sample degradation. The system can handle microplates or a variety of tube sizes and is considered ideal for the storage of nucleic acids, tissues, proteins, and compounds.
More: www.hamilton-storage.com
Harvard Apparatus
Pump 11 Plus Syringe Pump
According to Harvard Apparatus, this new low flow syringe pump specific flow rates or target volumes to be set, allowing for accurate delivery of fluids. Choose from the standard infusion only models, or the advanced infusion/withdrawal models with dual RS232 serial ports for computer control or daisy chaining multiple syringe pumps. For microflow rates, the Pump 11 Pico Plus syringe pump is considered ideal for cellular injections, FIA, or capillary LC applications.
More: www.harvardapparatus.com
Heidolph Brinkmann
Application Note: Lara CLR for Polymerization Control
Heidolph Brinkmann offers a new application note that demonstrates how the Lara Controlled Laboratory Reactor (CLR) is able to accurately and reproducibly control polymerization experiments. The note describes how the Lara CLR is used to automatically control the addition of monomer, initiator, and reagent where both linear and variable rates of addition of feed materials are used, and demonstrates that the Lara CLR can automatically ensure that the molecular weight and structure of the resulting polymer can be predicted, controlled, and reproduced.
The first experiment is run with a predetermined increasing monomer addition rate. The second experiment is run with a linear rate of monomer addition and a decreasing variable rate of initiator addition. In both, the monomer addition rate is gradually increased over several hours to ensure that the relative concentration of monomer stays constant throughout the multiple feed step of the reaction. The test polymerization reaction was exothermic, so experiments included the use of feedback loops.
Technical Bulletin: Lara CLR for Acid Chloride Coupling Reaction
A new technical bulletin from Heidolph Brinkmann describes how acid chloride is automatically fed over a 3-h period into the Lara CLR together with simultaneous sodium hydroxide addition to control the pH in the region of 6.5. The coupling of the acid chloride to the sodium salt of an oxy anion is a biphasic reaction in which the temperature has to be maintained at 10 °C to maximize yield of the final ester product. Efficient stirring of the coupling reaction is essential as the product forms a thick slurry.
According to Heidolph Brinkmann, the experimental data demonstrates that the Lara CLR was well suited for automating chemistry of this complex nature where pH control, reaction viscosity, and isothermal temperature control were all challenges to maximizing yield. With minimal training, the users were quickly able to set up the system, get the unit running, and reproducibly perform the acid coupling reaction to generate high yields of the ester product.
Insight Pharma Reports
GPCRs: Dawn of a New Era?
According to Insight Pharma Reports, this new report explores current and likely consequences of recent advances concerning GPCR, including X-ray structures, allosteric interactions, multimerization, and functional selectivity. It extensively tabulates marketed drugs and compounds in development arranged by receptor type and subtype, and presents in-depth interviews with experts in the field.
INTEGRA Biosciences
VIAFLO Voyager Handheld Pipettors
According to INTEGRA, its new VIAFLO Voyager range of handheld 8- and 12-channel electronic pipettors is designed to increase the productivity of liquid-sample transfers at a time for a fraction of the cost of an automated sample-handling system. Based upon a proprietary motorized adjustable spacing design, Voyager pipettors eliminate cross contamination and ensure consistent, accurate delivery of liquids to target vessels. Voyager electronic pipettors are considered ideal for applications including sample reformatting, PCR reaction set-up, ELISA sample transfers, and Taqman Assay set-up.
Voyager 8-channel pipettors serve as an efficient tool for transferring fluids out of tubes in racks that are spaced more than 9.0 mm apart into 96-well format plates. Four 8-channel Voyager models are available in volumes ranging from 0.5 up to 1250 μL. Voyager 12-channel pipettors serve as an efficient tool for simultaneously transferring 12 fluids out of tubes or plates that are in racks spaced more than 4.50 mm apart into 96-well format plates. Two 12-channel models are available: a 0.5–12.5 μL and a 5.0–125 μL.
MEDIACLAVE
The new MEDIACLAVE product range is intended to enable rapid and reliable preparation of 1–30 L of high-quality culture media. It is available in 10- and 30-L configurations, quick to set-up, and features an intuitive multilingual user interface.
Facility for pressure and temperature controlled deaeration allows out gassing of the sterilization chamber, and automatic in-process sterilization of the dispense port eliminates contamination risks. A flow heater system provides highly efficient heat transfer to ensure high temperature time and thermal stress to the culture media is minimized. Adjustable speed, bidirectional stirring guarantees complete mixing and prevents coagulation for production of absolutely homogeneous media. Rapid and gentle cooling using a highly efficient plate heat exchanger delivers culture media with the optimal bacterial fertility.
The new MEDIACLAVE is equipped with several independent monitoring systems for pressure and temperature, and supports stringent process documentation and validation needs. An integrated web server provides remote Ethernet connection and monitoring of the sterilization process and instrument parameters.
Malvern Instruments
Web-Based Seminars
A new and expanded calendar of free online Web seminars and other online events is now available at the Malvern Web site. The site also offers an archive of past Webinars, on-demand presentations, and other education and training opportunities.
More: www.malvernevents.com
ISys Software
A 64-bit edition of Malvern's ISys chemical imaging data analysis software, which has applications across a number of different technologies, is now available. ISys provides a single platform to supports the import of MIR, NIR, and Raman imaging and mapping data files from a variety of vendors. Thirty-day trial versions of both the new 64-bit edition and established 32-bit editions can be downloaded free of charge.
Mettler Toledo
ErgoClips
Suitable for use with XP and XS Analytical Balances and XP Micro Balances, ErgoClips allow safe dosing of samples directly into tare vessels without needing to use weighing paper. In addition, ErgoClips guarantee perfect positioning of a variety of small or unusually shaped tare containers, including HPLC vials, test tubes, Eppendorf and PCR tubes, flat-bottomed flasks, and volumetric flasks from 1 to 100 mL. ErgoClips are tailored for applications to simplify and speed up weighing processes, and are considered especially beneficial for toxic or valuable samples. Complementing the ErgoClips, the MinWeigh door with its small adjustable opening also promotes faster, more precise dosing.
More: www.mt.com/ergoclips
NextGen Sciences and Expression Pathology
Quantitative Protein Biomarker Assay for Determining Expression Levels in FFPE Tissue Samples
According to NextGen Sciences and Expression Pathology, they have a protein biomarker assay methodology that provides, for the first time, rapid, reproducible, quantitative measurement of protein expression in formalin fixed paraffin embedded (FFPE) tissue samples. The assay methodology uses Expression Pathology's Liquid Tissue reagents and protocols for sample preparation and to solubilize the entire protein content from standard FFPE tissue. The solubilized proteins are then assayed by NextGen Sciences using multiple reaction monitoring, a method for quantitation of proteins using mass spectrometry. The results correlate directly with those obtained by current immunohistochemistry techniques, but the new method is faster, straightforward, and provides accurate and quantitative measurement of protein biomarkers.
More: www.nextgensciences.com or www.expressionpathology.com
Novozymes Biopharma and Millipore
CellPrime rTransferrin AF
CellPrime rTransferrin AF is the first product launched by the Novozymes Biopharma and Millipore alliance to supply animal-free cell-culture supplements for bioprocessing, and according to the companies, is the first animal-free alternative to serum-derived human or bovine transferrin for industrial cell culture and upstream biopharmaceutical applications. Benefits over current plasma-derived alternatives include facilitating effective iron uptake into cells for optimal cell culture.
Paraytec
ActiPix Dissolution Imager
According to Paraytec, its new ActiPix Dissolution Imager provides a dissolution imaging capability that does not require expert operation. Using a specially designed tablet holder, controlled release pharmaceuticals can be studied using Paraytec's ActiPix D-100 UV area imager. The holder is placed inside the ActiPix D-100 that enables real-time recording and review of data. When liquid flows over the surface of the formulation, release of the active ingredient can be quantitatively monitored directly at the tablet surface.
More: www.paraytec.com
PerkinElmer
SMS100 Analyzer
Designed to improve the detection and measurement of mercury in solids and liquids and help minimize the need for complex sample preparation, the new automated SMS 100 analyzer complements PerkinElmer's EcoAnalytix portfolio. The SMS 100 uses thermal decomposition, gold amalgamation, and cold vapor atomic absorption spectrometry. Standardization can be accomplished using either liquid or solid standards. Additional features include a high-capacity autosampler.
More: www.perkinelmer.com
AAnalyst 50 Atomic Absorption Spectrometer
According to PerkinElmer, this new entry-level flame atomic absorption spectrometer offers double-beam technology for shorter warm-up times and improved signal stability, and requires fewer operator adjustments than a single-beam system. The AAnalyst 50 comes with a background corrector and a complete safety interlocks system, and features a mechanism to automatically power off in a safe sequence when any safety interlock is compromised. The system also checks and verifies the safe and proper installation of the sample introduction components each time the instrument starts. The AAnalyst 50 also includes PerkinElmer's dual option burner and sample introduction system.
Flexar LC Platform with Chromera CDS
According to PerkinElmer, its new Flexar liquid chromatography (LC) platform, which is controlled by the new Chromera chromatography data system (CDS), offers a new ergonomic industrial design and delivers a wide range of pressure options intended to address the increasingly demanding application needs of high-pressure liquid chromatography (HPLC) laboratories.
The Flexar UHPLC Systems feature the new FX-15 UHPLC system, which can provide as much as a 10-fold gain in productivity, while reducing mobile phase solvent consumption by as much as 15-fold, depending on the application. Smaller particle size (<2 μm) columns offer new possibilities for resolution and separations, as well as allow for faster analysis time.
The new Chromera CDS can rapidly visualize data and efficiently communicate results through an accessible worktop. The platform uses a technology for instrument control that allows flexibility of configurations and multiple detection capabilities.
PerkinElmer says Flexar is the only product line on the market that offers complete LC systems ranging from 6 to 10 to 15 k psi operation. Users have a choice for instrument control with the new Chromera workstation-based CDS or TotalChrom for those who require a regulated or client-server—based CDS system.
More: www.perkinelmer.com
Differential Scanning Calorimeters
According to PerkinElmer, its new line of four high-performance differential scanning calorimeters (DSCs) is designed to improve accuracy, sensitivity, and performance in thermal analysis. The DSC 4000 single furnace solution is applicable for a wide range of routine applications in the academic, polymer, and pharmaceutical markets. The DSC 6000 builds upon the key features of the 4000 with the addition of modulated temperature DSC, additional accessories, and enhanced electronics to enable users to separate kinetic events from thermal events and interpret data with greater ease. The DSC 8000's core double furnace technology is designed to rapidly heat and cool materials and to assist in replicating the processes encountered in the product development of polymers. This controlled heating and cooling is intended to enhance accuracy in testing results. The DSC 8500 offers the same core double furnace technology benefits of the DSC 8000, and allows rapid controlled heating to 750° per minute and ballistic cooling to 2100° per minute to quench a sample without removing it from the instrument. The fast heating and cooling can help reduce overall analysis times from the standard 45 to 3 min. This productivity improvement is enhanced when the DSC 8500 is fitted with an optional 96-position autosampler.
LABWORKS LIMS 6.1
According to PerkinElmer, its LABWORKS base product is a flexible platform that can be quickly deployed and configured to match the specific needs of a laboratory and/or industry. LABWORKS 6.1 retains these key features while allowing users to take advantage of a Web connected device for information access. LABWORKS 6.1 software features LABWORKS WebTop, a zero footprint platform requiring no software installation on the mobile device and allowing the customer to use any available Web browser to access product testing results when and where they are needed.
More: www.perkinelmer.com
Swafer Microchannel Wafer for the Clarus
A new microchannel wafer technology platform for flow-switching applications in capillary gas chromatography is now available from PerkinElmer. Swafer technology provides Clarus Gas Chromatograph users with additional application flexibility, while delivering richer sample information, increased sensitivity, lower maintenance costs, and increased sample throughput.
From simple techniques like connecting two detectors to one column and removing unwanted material from a column, to sophisticated multidimensional separations on complex samples, Swafer's capabilities cover a wide range of applications.
Two versions of the Swafer are now available. The S-Swafer is a scalable splitting device designed for sample-stream splitting between a range of detectors or columns. The D-Swafer is based on the classic Deans' Switch principle. Both the S-Swafer and the D-Swafer can be configured in multiple ways.
PerkinElmer and Waters
Interface Software for Empower 2 Chromatography
A new chromatography interface software for the Waters Empower 2 Chromatography Software allows control of PerkinElmer Clarus Gas Chromatographs, which include the 600, 500, and 400 models, and TurboMatrix Headspace Samplers on existing Waters Empower 2 Chromatography Software networked installations. This collaboration with Waters will combine the strengths of both companies, and promises to benefit customers by delivering a more integrated solution for users requiring multivendor compatibility.
More: www.perkinelmer.com
Porvair Sciences
1-mL Protein Precipitation Cartridge
The new 1-mL Protein Precipitation Cartridge combines the operational benefits of Porvair's p3 technology with the low cost and convenience of a cartridge-based separation methodology. Incorporating a novel-treated dual matrix frit, the new p3 cartridge eliminates the wetting out and leaking of sample associated with many traditional protein precipitation products before the application of vacuum. The novel-treated frit matrix also maintains high flow rates enabling quick sample preparation times. In tests, p3 cartridges do not have any major adverse nonspecific binding problems.
More: www.porvair-sciences.com
BioVyon C18 Silica Columns and Microplates
A new range of BioVyon C18 silica columns and microplates is now available from Porvair Sciences for use in low volume solid-phase extraction (SPE) assays. According to Porvair, immobilizing the C18 sorbent within the porous BioVyon polymer has created a novel, high-surface area matrix that provides unmatched control of flow rate. In addition, the immobilized C18 sorbent cannot form liquid channels and does not require inert frits to support it thereby minimizing hold-up volume. The combination of these attributes enables this new range of SPE columns and microplates to provide higher consistency and greater recoveries for small sample-volume assays.
BioV yon C18 is offered in 96-well microplates as a 10 mg per well loading suitable for low-volume bioassay preparation and clean-ups. In the 1-mL cartridge format, BioVyon C18 is available in a choice of 12.5-, 25-, and 50-mg loadings.
More: www.porvair-sciences.com
Radleys
Lara Lite CLR
Lara Lite is a manually Controlled Lab Reactor (CLR) that eliminates the need for multiple reaction set-ups. It includes a dedicated push button speed control box with LCD display that provides electronic control from 70 to 1000 rpm with additional torque display. Lara Lite also features an RS232 interface for optional PC speed control and logging using any generic control software. Lara Lite is designed to replace the requirement for multiple glass reaction set-ups in multiple fume hoods, and can accept jacketed vessels from 100 mL to 10 L.
The Lara Lite integral hinged stirrer drive automatically ensures correct stirrer alignment to enable ultra-stable stirring without vibration, a significant reduction in experimental set-up time, full access to the reactor lid and ports, and a reduction of the overall unit height to fit into a standard fumehood. The Lara Lite quick-release vessel clamping mechanism allows reaction vessels to be safely exchanged in minutes without tools. A novel semiautomated drain down facility allows it to rapidly drain down reactor circulation fluids in experiments that require a reactor exchange, eliminating the hazards and mess associated with spilt circulation fluid. To maximize recirculation efficiency, unrestrictive quick connector couplings do not impede oil flow.
More: www.lara-clr.com
RTS Life Science
A-Range Automated Sample Storage Systems
According to RTS, its A-Range of automated sample storage systems makes extensive use of industrial quality robotics, combined with powerful but user-friendly software, to offer flexible solutions for small sample collections through to multimillion sample libraries.
The RTS A2 is the smallest store in the A-Range, specifically designed for collections up to 150,000 samples, but where the benefits of cherry picking and improved environmental control are still required. This modular solution, using industry standard robotics, can be quickly installed and has minimal facilities requirements.
The RTS A3 SmaRTStore can store up to 360,000 samples in a very small footprint, offers the highest storage density in its class, is suitable for storing compounds or DNA, and multiformat storage and picking capabilities are standar. The A3+ model is an extended version of the A3, offering an additional 50% storage capacity.
For applications where a central archive or satellite storage system is required, the RTS A4 uses vertical-lift technology and its flexible configurability enables up to 2,000,000 samples to be stored in a very small footprint. Its multiformat capability allows the storage of plates, tubes, and vials in the same unit, with options for multifloor level configurations.
Finally, the RTS A5 systems support large-scale compound management by using narrow-aisle robots to access banks of high-density storage racking. Both the A5 Compact Store and A5 Sample Store are at the premium end of the RTS product range, with both solutions providing space-efficient storage for a wide range of sample types under a variety of storage conditions.
More: www.rtslifescience.com
Schaffner
ECOsine Active Harmonics Filters
According to Schaffner, its new digital ECOsine active harmonics filters provide real-time mitigation of harmonics and immediate compensation for voltage dips and reactive power surges.
ECOsine active filters continuously measure and analyze disturbances in the power network and provide an exactly opposite compensation current. In doing so, the filters actively adapt to changing network topologies and respond in less than half a millisecond. In addition to the global or selective mitigation of harmonic currents up to the 50th order, ECOsine active filters can perform targeted power factor correction. ECOsine active filters are compatible with international harmonics standard IEEE 519 as well as with local utility codes, and their electrical infrastructure is unburdened. They are available in 3-phase/3-wire as well as 3-phase/4-wire configurations for 480 and 400 V grids, respectively, and with rated compensation currents from 30 to 300 A. All three-wire filters are UL listed.
More: www.myecosine.com
SP Industries
Lyostar3 Pilot Plant Freeze Dryer
SP Industries' Smart freeze dryer technology combined with other primary drying end point detection methods enable the LyoStar3 to deliver maximum programming flexibility and product protection whether the product is processed in vials, bulk trays, 96-well plates, or syringes. GE Proficy iFIX 5.0 software allows programmable pressure ramping to better match commercial scale systems, conditions, and features. LyoStar3 also features superior shelf mapping, fast shelf freezing, stoppering for vials, ease of use, and high reliability.
More: www.spindustries.com
Virtis Advantage Plus Laboratory Freeze Dryer
According to SP Industries, its new Virtis AdVantage Plus laboratory's freeze dryer is a new budget-priced version that includes a package of popular accessories. Packaged data collection and graphic trending software, stainless steel product trays, MVP product thermocouple probe positioning assembly, and a complete 600-mL filter seal flask assembly are now offered free of charge on all new systems.
The AdVantage Plus can freeze dry bulk product or be configured for applications in stoppered vials. Side-mounted manifold valves provide the additional flexibility to freeze dry product in flasks. Three refrigeration choices are available for the large 6-L capacity condenser, depending on the type of product and solvents being lyophilized. The AdVantage Plus can be configured with up to three fluid-cooled shelves that maintain precise temperature control previously available only in pilot and production scale units. The Advantage Plus measure 26 in. (66 cm) wide and enables product to be safely processed on over 3 ft2 (2900 cm2) of usable shelf area.
More: www.spindustries.com
Starna Scientific
UV Linearity Reference Sets
Starna Scientific has extended the absorbance scale range of its potassium dichromate linearity set of certified reference materials to address multipoint linearity checks across the UV absorbance range. The use of potassium dichromate solvated in dilute perchloric acid is an established method for the validation of the absorbance scale and linearity of a spectrophotometer in the UV region, and Starna's new offering can prove the linearity of the spectrophotometer UV absorbance scale up to 3.5 A using a range of 0–240-mg/L solutions.
Full documentation on measurement, handling, and storage is also provided with each set of CRMs.
More: www.starna.com
Symyx Technologies
DiscoveryGate Web Service
According to Symyx, its new DiscoveryGate Web Service provides platform-independent, remotely hosted scientific content for direct consumption by users' internal applications and services, as well as Symyx software applications. DiscoveryGate is designed to accelerate scientific workflows, decision making, and productivity in R&D by providing programmable 24/7 access to current chemical sourcing, molecular property, synthetic methodology, bioactivity, and toxicology information from Symyx and participating content providers.
More: www.symyx.com/products/software/database-access/web-services/index.jsp
Symyx Notebook 6.2
The latest release of this enterprise electronic lab notebook supplements existing functionality for analytical chemistry research and biology with new capabilities supporting synthetic and medicinal chemistry investigations. According to Symyx, this is achieved by adding Symyx chemical representation, chemical reaction, and compound registration functionality to the core product. The Symyx chemistry engine powers the ISIS scientific information platform that underlies many chemistry registration, inventory, and other systems. In addition, Symyx Notebook 6.2 adds essential chemistry information enabling scientists to access current chemical sourcing, molecular property, synthetic methodology, bioactivity, and toxicology information from Symyx and participating content providers in the context of laboratory workflows.
Symyx Technologies Europe
Symyx Screening Pressure Reactor
According to Symyx Technologies Europe, its new Symyx Screening Pressure Reactor (SPR) is a high-throughput research system that enables up to a 100-fold increase in the speed of screening and optimizing catalysts and catalytic processes. The Symyx SPR is available for refining petrochemical and fine chemical applications. It encompasses Symyx's chemistry, engineering, and software expertise to perform experiments in parallel and in miniature with precision, speed, and reliability.
More: www.symyx.com
Syrris and Prosonix
Atlas SonoLab
The Atlas SonoLab System is a high-performance, automated ultrasound system for sonocrystallization, sonomilling, and sonochemistry. Combining the Syriss Atlas jacketed reactor platform with Prosonix's new SonoLab ultrasound technology enables the reproducible control of crystallizations and allows selectivity of parameters such as particle size, shape, crystallinity, and polymorph.
According to Syrris, advanced control of nucleation and growth rate enables the production of extremely pure results for a high-quality final product. Batch-to-batch consistency is maintained via automated control of the process parameters and nucleation, to provide extremely reproducible results. Controlling nucleation without using external seed crystals avoids consistency issues and increases selectivity, and using SonoLab equipment in conjunction with the Atlas platform provides a basis for quality ultrasonic experiments and a seamless transition from laboratory to pilot plant at scales ranging from 100 mL to 100 L. In addition, laboratory results can be successfully implemented at manufacturing scale using the Prosonitron range of instruments.
More: www.syrris.com
Thermo Fisher Scientific
Technical Poster: Integrating Informatics and High Content Screening to Find a Cure for Spinal Cord Injury
Co-authored by scientists from the University of Miami Miller School of Medicine and senior technical managers from Thermo Fisher Scientific, this new poster demonstrates how the university's LemBix laboratory implemented an informatics solution to manage the enormous volumes of data generated by The Miami Project to Cure Paralysis where a single experiment can generate data from 300,000 neurons with 140 parameters per cell.
More: www.thermo.com/eThermo/CMA/PDFs/Product/productPDF_50097.pdf
Application Note: Fast Multiresidue Pesticide Analysis Using Triple Quadrupole GC—MS/MS
This new application note discusses how modern food safety testing laboratories can take advantage of the fast acquisition rate provided by the TSQ Quantum GC to achieve rapid analysis of multiresidue pesticides. The TSQ Quantum GC is used in conjunction with a Thermo's TRACE GC Ultra gas chromatograph, TriPlus autosampler configured for liquid injection, and TRACE TR-5MS analytical column for chromatographic separation.
According to Thermo, this system is capable of achieving high sample throughput with a total of 170 pesticide components being screened with high sensitivity in a single injection in only 20 min. Excellent sensitivity, selectivity, and flexibility are achieved by using up to 25 transitions in 11 retention time windows. False positive results due to cross talk are safely excluded even under fast acquisition cycles.
Online Resource for Nalgene and Nunc Bioproduction Products
A new Web site enables users to stay up to date with new technology, solutions, promotions, and expertise to streamline and scale-up production by allowing users to build processes, find technical references, request validation information, and perform detailed product searches. It also provides direct access to the Online Custom Tubing Set Configurator, a tool that enables design of integrated fluid transfer and bioprocess systems using Nalgene and Nunc products.
Nalgene Bioprocess Bag Management Systems
To provide an organized and systematic means of managing flexible containers for bulk intermediate reagents and solutions, this new system's rigid, puncture-resistant polycarbonate shell top and bottom form a protective barrier around a bioprocess bag to isolate and stabilize the bag and tubing during transport.
Nalgene Certified Clean PETG Containers
According to Thermo, these new containers are suitable for pharmaceutical and biotechnology applications requiring the processing and storage of bulk intermediates and critical reagents such as vaccine and protein therapeutic preparations. The containers provide excellent gas barrier properties to minimize pH shifts. Resins used to produce these containers are free of animal derived components. The bottle and closure system is guaranteed leakproof.
More: www.nalgenelabware.com
Thermo Scientific Connects
Thermo Scientific Connects is a new program aimed at bridging the gap between laboratory-generated data and the enterprise-level information required for management decisions. It comprises a set of offerings that leverage the company's breadth of laboratory information management systems (LIMSs) and chromatography data systems (CDS) capabilities, as well as expertise in enterprise systems integration to help streamline and improve the transfer of knowledge between laboratory-generated data and enterprise-level information systems.
This comprehensive solution set includes a combination of Thermo Scientific instruments, LIMS and CDS software, tools and services, and capitalizes on ongoing partnerships with technology companies including Microsoft, SAP, Oracle, and enterprise Electronic Laboratory Notebook providers like Symyx Technologies, document management systems companies like NextDocs, and members of the company's Global Partner Alliance, a network of partners that delivers local and regional support.
TSQ Vantage
According to Thermo, its new LC—MS/MS system delivers up to 10 times more sensitivity than any other triple quadrupole instrument on the market, without a commensurate increase in noise. New technical breakthroughs have given the TSQ Vantage unmatched signal-to-noise performance, providing better reproducibility and precision in the quantitative analysis of small molecules, biomolecules, and peptides.
The new S-Lens ion optics system in the TSQ Vantage uses novel electrostatic field technology to capture virtually every ion and efficiently transfer it into the Thermo Scientific HyperQuad quadrupole mass analyzer. The S-Lens design eliminates mass discrimination and lowers the gas load on the expensive turbo-molecular pumps, keeping the ion optical path cleaner, for a longer period of time, while maintaining sensitivity.
To maximize the workflow capabilities of these advanced LC—MS/MS technologies, the company recommends its Thermo Scientific Transcend, an advanced online sample extraction system for the analysis of complex matrices on the mass spectrometer. The Transcend system doubles sample analysis while reducing sample preparation time and increasing detection limits by leveraging instrument sensitivity, auto-sampling, and LC columns.
Sorvall ST 40 Centrifuge Series
According to Thermo, its new Sorvall ST40 3-L, general-purpose centrifuge series provides capacity and ergonomic advancements for everyday sample preparations. Both the Sorvall ST 40 and the Sorvall Legend XT centrifuges feature the Auto-Lock III rotor system, which enables 5-s rotor exchange without the need for tools for fast switching between applications. Operation is further simplified by a motorized lid latch and the ClickSeal bucket sealing system with a glove-friendly, one-handed open/close capability for certified biocontainment of samples. With advanced rotor management SMARTSpin technology, acceleration, braking, temperature control, and load balance is optimized for smooth runs and reproducible data. The user-friendly, backlit interface provides detailed information on operating parameters and the dedicated fast keys enable immediate access to frequently used programs.
Hamilton Infinity Fume Hoods
According to Thermo, its new Hamilton fume hoods offer enhanced ergonomics, and address ever-increasing requirements for safety, energy efficiency, and aesthetics. Optional GreenFumeHood technology eliminates atmospheric pollution from the exhaust, minimizing building infrastructure and can dramatically reduce energy consumption costs.
More: www.thermo.com/hamilton
Hamilton Distinction II Adaptable Laboratory Furniture System
Thermo's new Hamilton Distinction II Adaptable Laboratory Furniture system workstations offer an adaptable design for easy integration, and a contemporary look to enhance both functionality and aesthetics. Each modular unit is environmentally friendly, constructed from reclaimed steel, combined with components from renewable sources such as bamboo, agriboard, and medium-density fiberboard. This design enables laboratories to meet the leadership in energy and environmental design criteria.
More: www.thermo.com/hamilton
Revco PLUS HD Ultra-Low Temperature Upright Freezer Range
This new extension of the Revco PLUS line features thin-wall insulation (HD) technology to maximize interior storage capacity without increasing the footprint of the cabinet. The Revco PLUS HD freezer range is available in 25- and 32-ft3 models, with the latter offering a market-leading capacity of 70,000 samples in the same footprint of a conventional 25-ft3 freezer. According to Thermo, a patented refrigeration system and a robust electronics platform provide excellent energy efficiency, temperature stability, and fast recovery times across the entire range, ensuring the highest possible sample integrity.
More: www.thermo.com/revcoplus
Aspire RP30 Desalting Pipette Tips
According to Thermo, its new Aspire RP30 Desalting Pipette Tips purify, desalt, and concentrate peptides or low molecular weight proteins (65 kDa or less) and complex protein samples before LC/MS and LC/MS/MS analyses. The Aspire tip is a 200-μL pipette tip containing a bed of proprietary Styrene-divinylbenzene reversed phase resin. The Aspire tips offer higher binding capacity (∼4–6 fold higher) compared with conventional C18 desalting tips, allowing purification of up to 30 μg of total peptide from 15- to 200-μL sample volumes. The Aspire tip purification method uses a color-coded, multichannel protocol, which streamlines low-to-medium throughput sample cleanup. Without the need for centrifugation, 12 samples can be rapidly processed in parallel within 20 min. More: www.thermo.com/aspirerp30
Maybridge Quick2Lead Compound Kits
Maybridge Quick2Lead Compound Kits are designed to enable rapid compound library synthesis around bioactive hits emerging from screening assays. The kits are made up of preweighed, diverse building block selections, facilitating rapid capture of structure—activity data from the closely related structural analogs within the library.
Quick2Lead Compound Kits are available as 5 functionality based kits, with each one containing 48 compounds, and ready to use by simply adding solvent and transferring straight to a synthesizer. The available kits include carboxylic acids, sulfonyl chlorides, amines, anilines, and boronic acids. Each of these different functional groups is applicable to a wide range of parallel synthesis methodologies, and although each kit taps into the Maybridge collection, they all also include compounds from the top levels of the relevant Topliss Tree. Each of the preselected compounds is supplied as 0.1 mMol in a 5-mL vial.
More: www.maybridge.com
Varioskan Flash and LanthaScreen Assays
Varioskan Flash spectral scanning multimode reader is now certified for use with LanthaScreen assays from Invitrogen. The LanthaScreen assay is an advanced time-resolved fluorescence energy transfer (TR-FRET) technology. Using the time-resolved fluorescence technology of the Varioskan Flash, biological background interference is minimized, improving sensitivity in cellular assays. The flexibility of the Varioskan Flash in combination with the LanthaScreen platform enables rapid application of TR-FRET technology to multiple target classes across a wide range of application areas, such as second messenger, kinase, or hormone receptor assays.
Thermo Fisher Scientific and SIEMENS
Advanced PAT Applications
Thermo has combined its Antaris family of FT-NIR analyzers and the SIEMENS SIPAT software platform. According to Thermo, the integration is a natural extension of the Antaris analyzer product line, and is designed to allow pharmaceutical companies to further extend the capabilities of the FT-NIR analyzers to achieve better process insight, real-time product release, improved manufacturing performance, and enhanced quality while maintaining regulatory compliance. This initiative creates a solution tailor made to the needs of the pharmaceutical industry that seamlessly migrates process analysis from the laboratory into production, effectively mitigating risk and is intended to drive significant cost savings.
More: www.thermo.com/nir
Torrey Pines Scientific
EchoThermo Digital Hot and Stirring Plates
The EchoTherm Models HP50 and HS50 Digital Hot Plates and Digital Stirring Hot Plates are compact, rugged, and designed for samples of 2 L or less. The units feature a membrane keyboard and full function liquid crystal display where target and actual sample or plate temperature, stirring speed, and timer are continuously visible. These units can store two of the user's favorite settings in memory for instant recall and use at any time.
Heater tops are 6″ × 6″ square and feature energy efficient 400-W heaters. The solid ceramic plate is white, chemically resistant, and designed for use with solutions in a vessel. The milled-flat cast aluminum top is recommended for working with solids directly on the heater plate surface. Temperatures can be set to 450 °C on the ceramic-topped units and to 400 °C on cast aluminum tops. The units are readable and settable to 1 °C. Accuracy is 1% over the entire temperature range.
Temperature control is by PID software and is controlled to ±1 °C or °F. Stirrer speeds can be set from 100 to 1500 rpm. The built-in timer can be set to 99 h and is readable to 1 s. It has an audible alarm with user settable auto-off for turning off the heater and stirrer when the timer counts down to zero. The units are supplied with an immersion probe for controlling solution temperatures directly.
Tovatech
Elma High-Capacity Ultrasonic Cleaners
New high-capacity Elmasonic Ultrasonic Cleaner lines are available in volumes from 1 to 180 L (47.6 gal) for gentle, but thorough cleaning of pharmaceutical, automotive, medical, electronic, and other industrial parts. According to Tovatech, Elma units use powerful generators and transducers for ultimate performance. A microprocessor senses the load in the bath and modulates the ultrasonic generator to deliver the same cleaning power for every run. Heating elements are protected against overheating. Bath temperature can be maintained with a cooling coil accessory.
Uniqsis
Cold Tray Reactor Module for FlowSyn Continuous Flow Reactor
A new interchangeable reactor tray is now available for the Uniqsis FlowSyn Continuous Flow Reactor, and can be fitted retrospectively to existing FlowSyn systems in a few minutes. Used with a suitable heater/chiller unit and an appropriate thermal fluid, the system has a validated temperature range from −40 to +150 °C, and will maintain stable low temperature conditions for extended periods. Control is via the standard FlowSyn user interface.
More: www.uniqsis.com
Zinsser Analytic
Qualyvials R
Zinsser Analytic offers a new generation of standard sample vials for robotic applications. According to Zinsser, its new Qualyvials R are manufactured to high standards from borosilicate glass within very close tolerances.
More: www.zinsser-analytic.com
More News
Accelerated Technology Laboratories entered into a partnership with the David H. Murdock Research Institute (DHMRI) to exclusively provide its Sample Master Pro LIMS platform for use throughout DHMRI's North Carolina Research Campus. The Sample Master Pro LIMS will manage data and facilitate discovery by allowing the integration of data generated from separate core laboratories, including genomics, metabolomics, proteomics, light microscopy, electron microscopy, and NMR. Agencourt Bioscience announced that its Genomic Services group purchased an Illumina Genome Analyzer II (GAII) for its next-generation sequencing suite. With installed 454 Life Sciences Genome Sequencer FLX and Applied Biosystems SOLiD instruments used in production, Agencourt says the addition of the GAII makes it the first commercial DNA sequencing service provider worldwide with comprehensive next-generation services. Arrayjet installed its Marathon or Super-Marathon Inkjet Microarrayers in the UHN Microarray Centre, USAMRIID, Cornell University, and a large Bay Area biotechnology company. The Artel Technical Services team added Candie Cavosora as a customer support specialist to coordinate the company's pipette proficiency training program. Biochrom launched Biochrom US, headquartered in Holliston, MA, to support the North American distribution of the WPA and Libra ranges of UV/VIS spectrophotometers and colorimeters, plus the Asys and Anthos brands of microplate instrumentation. BioFocus DPI and the Medicines for Malaria Venture started a collaboration to use BioFocus DPI's natural product and SoftFocus compound collections for the identification of new natural product and small molecules that demonstrate antimalarial activity. BioFocus DPI and TET Systems entered into an agreement to apply TET System's inducible gene technology in high-throughput screening campaigns performed for BioFocus DPI customers. BioMosaics announced that its monoclonal antibody product (clone 1G12) for detection of Glypican-3 was validated for use as an immunohistochemical test for diagnosis of Hepatocellular Carcinoma by PhenoPath Laboratories. BioTek Instruments received the Supplier of Choice Award from Fisher Scientific Canada. Fisher Scientific's instrument specialists and general sales representatives voted for the supplier that provided the best overall support to help grow Fisher's instrumentation business. BioTek Instruments was one of 5 large companies and 10 small-to-medium companies honored with Best Places to Work Awards sponsored by Vermont Business Magazine and supported by the Vermont Chamber of Commerce, Vermont Society of Human Resource Management, and the Vermont Departments of Labor and Economic Development. BioTek was recognized in the large companies category. BioTek Instruments also announced the incorporation and expansion of BioTek Instruments Singapore. This new and independent company will provide support for the Asia Pacific distribution network and end-user customers. New office space includes conference suites and a demonstration facility for application optimization and training on several advanced BioTek microplate technologies. Cresset Biomolecular Discovery signed a distribution agreement with CambridgeSoft allowing CambridgeSoft to sell Cresset's FieldAlign and FieldTemplater products. CyBio and Axxam developed, installed, and fully validated a new screening station to be used by Axxam in running hit discovery campaigns with automated luminescence and fluorescence screening systems. The new workstation, which runs in parallel to another CyBio workstation, is a customized, multifunctional automation platform that allows flexible adaptation to different assay conditions using high-density 384 plates. A central CyBi-Well vario high parallel pipetting system unites two major working areas. Cooled storage system, peeler, sealer, and plate heating stations frame the area for compound management. The screening area not only consists of a pipetting system, a dispenser, a washer, high-capacity stacking, and incubation devices with lid handling options, but also of two readers, a FLIPRTETRA (Molecular Device) and a PHERAstarPlus (BMG Labtech). deCODE genetics granted Celera nonexclusive worldwide licenses to deCODE's genetic markers for increased risk of major cardiovascular and metabolic diseases. These markers can be incorporated into laboratory tests for assessing and managing individual risk of these diseases. Evotec appointed Dr. Werner Lanthaler as chief executive officer. Previously, Dr. Lanthaler served as chief financial officer of Intercell. In recognition of the growing need for automation in living cell and tissue applications, the Finnish Automation Society awarded its biannual Automation Award to Micro- and Nanosystems Research group of the Department of Automation Science and Engineering at Tampere University of Technology. The research team led by Professor Pasi Kallio has been working in close collaboration with the Cell Research Center and the Institute for Regenerative Medicine of the University of Tampere, Chip-Man Technologies and the Biosensing Competence Centre for the past 10 years. The group's latest developments in automation technology assist stem cell researchers on functionalizing neuron and heart cells from embryonic stem cells. The research work also aims at reducing the use of laboratory animals in chemical testing by replacing them with primary human cell cultures. Fluidigm's integrated fluidic circuit technology is being used by the Columbia River Inter-Tribal Fish Commission's (CRITFC) genetic laboratory to conduct genetics research of salmon and steelhead in the Columbia River. CRITFC has been using Fluidigm's 96.96 Dynamic Array chip and the new EP1 System to process 96 single nucleotide polymorphism markers with 96 salmon DNA samples to provide 9216 simultaneous reactions per chip. Fluxion Biosciences announced an exclusive distribution agreement with EuroClone to handle sales and service of Fluxion's BioFlux research tools for live cell image analysis in Italy, Spain, and Portugal as well as countries in Eastern Europe and Northern Africa. The contract includes the Czech Republic, Slovenia, Croatia, Bosnia Herzegovina, Serbia, Montenegro, Albania, Bulgaria, Rumania, Greece, Turnkey, Cyprus, Malta, Libya, Morocco, Tunisia, and Algeria. Dr. Robin A. Felder, chairman and cofounder of Global Cell Solutions and professor at the University of Virginia, received the 2009 Engelberger Robotics Award for Leadership from the Robotics Industries Association. IDBS announced that BSL BIOSERVICE Scientific Laboratories purchased E-Workbook, and its biology extension, BioBook, for use in its GLP-regulated in vivo department where it will capture, search, protect, and share high value research and preclinical data on behalf of a broad spectrum of international clients. Innovation Matrix established a new division, EnergyMatrix, to better serve its customers with energy saving products, and EnergyMatrix announced an exclusive partnering with Chuo Electric Works. INTEGRA Biosciences installed 50 VACUSAFE comfort units to provide aspiration of biological samples at the Centre for Biomedicine and Medical Technology Mannheim. The entire product range of Viscotek GPC/SEC, dilute solution viscosity, and light scattering systems in India are now being managed direct in the region by Malvern Aimil Instruments. Micronic received a 12-month call-off order for sample storage tubes from the Rutgers University Cell & DNA Repository, the largest university-based repository in the world. After an open evaluation process, Rutgers selected Micronic 0.75- and 1.4-mL tubes together with colored TPE caps to provide high integrity, long-term storage of samples at −80 °C. NextGen Sciences sold its electrophoresis business to Sigma-Aldrich. According to NextGen, this divestiture is in line with its strategic plan to wind down its software and instrumentation U.K.-based businesses to focus on growing its biomarker services business. The deal involved the acquisition of the automated gel casting unit, the a2DEoptimizer and the optigels range of large format precast gels. Sigma-Aldrich will focus primarily on the supply of optigels, initially to the North American and European markets. Novozymes Biopharma signed a license agreement with GE Healthcare Life Sciences that enables Novozymes Biopharma to produce and deliver native, animal-free protein A, the production of chromatography media using GE Healthcare technology. Oxford Gene Technology acquired Sense Proteomic, a U.K.-based company engaged in the discovery of disease-specific biomarkers based on its functional protein array technology. PreAnalytiX, a QIAGEN/BD Company, received marketing clearance from the U.S. Food and Drug Administration for the automation of the PAXgene Blood RNA System on the QIAcube. This clearance enables laboratories to automate an IVD purification method that is part of an integrated IVD blood collection method for intracellular RNA. The Queen's Awards for Enterprise are bestowed each year by The Queen of England, on the advice of the Prime Minister, who is assisted by an Advisory Committee that includes representatives of government, industry and commerce, and the trade unions. For 2009, Queen's Awards for Outstanding Innovation were presented to Astech Projects for its Xelair series of automated systems, and to Thermo Fisher Scientific for its iCAP 6000 Series of Inductively Coupled Plasma, Optical Emission Spectrometry instruments. The Automation Partnership launched a new Advanced Projects Group division to work with biotech and academic customers to deliver customized automation to better enable bench-based research and process development. Thermo Fisher Scientific signed a partnership with Symyx Technologies to market and sell Symyx Notebook and Symyx Isentris decision support software. The collaboration is considered a key component of the Thermo Scientific Connects integrated solutions initiative. Waters Corporation and LabVantage Solutions announced a strategic partnership to integrate laboratory software for improved efficiency and effectiveness at laboratory dependent organizations. Collaborating with existing common customers, Waters and LabVantage had already successfully integrated LabVantage's SAPPHIRE Laboratory Information Management Suite with Waters NuGenesis Scientific Data Management System and Empower 2 Chromatography Data Software solutions. Researchers at the Weatherall Institute of Molecular Medicine adopted Chip-Man Technologies' Cell-IQ platform to study multipotent live cells during differentiation. The Institute's Molecular Hematology Unit is trying to understand the signaling pathways involved in hematopoiesis. Zinsser Analytic and ThalesNano signed a collaboration agreement for product distribution in the territory of Germany, Switzerland, and Austria.
Call for Papers
LabAutomation2010
ALA is now accepting abstract proposals for LabAutomation2010 podium and poster presentations in five key education tracks: detection and separation, high-throughput technologies, informatics, micro- and nanotechnologies, and evolving applications of laboratory automation featuring agriculture and food. One podium presenter will win $10,000 as the 2010 ALA Innovation Award winner, and 10 finalists will travel to Beijing, China, to present their work at ACHEMAsia2010, June 1–5.
The ALA LabAutomation2010 conference and exhibition will be held on January 23–27 in Palm Springs, CA. For complete program information and access to the online abstract submissions system, visit www.labautomation.org.
Journal of the Association for Laboratory Automation
JALA is the only peer-reviewed, scientific journal devoted exclusively to the research, development, and application of technologies in scientific laboratories. Manuscripts are accepted on an ongoing basis from ALA members and nonmembers.
JALA manuscript abstracts are indexed by Analytical Abstracts, Chemical Abstracts CAS+, CINAHL, Compendex, EMBASE/Excerpta Medica, Google Scholar, Inspec, ProQuest CSA Tech Research Database, Scifinder, Scirus, and Scopus. Abstracts and full text articles also are available at JALA Online and Elsevier ScienceDirect.
Lab automation professionals are invited to showcase their achievements by submitting method-focused scientific papers for publication consideration. Manuscript guidelines and submission information are available at www.labautomation.org/journal/submissions.cfm.