Abstract
Absorption Systems
CellPort Technologies Assay System
CellPort Technologies is a new assay system that can provide the preclinical in vitro data on drug transporter-mediated drug–drug interactions needed when submitting a new drug application. Using a series of novel cell lines in which transporter expression has been manipulated, in the bidirectional assay format designated by the FDA, the assay system clearly determines which efflux transporter(s) a test compound interacts with, if any.
For more information, visit www.absorption.com.
Arrayjet
Ultra-Marathon Inkjet Microarrayer
The new Ultra-Marathon is based on the same platform as its predecessors, the Marathon and Super-Marathon Inkjet Microarrayers, and uses piezoelectric inkjet technology for the high-speed production of high-quality microarrays. The Ultra-Marathon is available with and without the Microplate Stacker Module, and adds slide-handling capability to the platform to increase its capacity to 1000 1 × 3-in. (25 × 75 mm) glass slides. In isolation, according to Arrayjet, this represents a significant enhancement, but when combined with the Array Multiplier software module, which enables users to specify almost any number of miniarrays to be printed on each slide (space permitting), one could imagine 1000 slides each bearing, for example, 16 miniarrays. This means that a total of 16,000 microarrays could be produced in a single, fully automated print run.
For more information, visit www.arrayjet.co.uk.
Array Multiplier
The Array Multiplier software module brings additional capabilities and functionalities to Arrayjet's range of inkjet microarrayers, including the Marathon and Sprint microarray platforms, by enabling printing of multipad or miniarrays.
For more information, visit www.arrayjet.co.uk.
Aseptika
Bioreactor Sampler
According to Aseptika, sampling bioreactors and fermentors takes around 15 s and eliminates risk of contamination with the new, single-use, Aseptika Bioreactor Sampler. The Bioreactor Sampler has a unique system that withdraws samples through its nonreturn valves.
For more information, visit www.aseptika.com.
Asynt
Compact Reaction Station for Viscous Mixtures
The Vortex stirrer system from Asynt's DrySyn range converts a single overhead stirrer into a powerful three position parallel stirrer combined with a multiple heating block. The combination provides efficient stirring while retaining all the DrySyn benefits—improved safety, rapid heat transfer, and space saving. Used with a standard laboratory hotplate, the unit becomes a very compact, small footprint reaction station capable of running up to three parallel reactions in conventional round-bottomed flasks—no special flasks are needed.
For more information, visit www.asynt.com, e-mail
Bel-Art Products
Scienceware Spinbar Capsule Magnetic Stirring Bar
Designed to eliminate the destructive-force shakers and loose stirring bars can have on delicate gels by gently mixing destaining solutions, the Spinbar Capsule Magnetic Stirring Bar spins freely inside a small flat capsule to prevent contact with gel. The large footprint of the capsule allows it to be positioned in the bottom of vertical electrophoresis units and stir buffers without wandering.
For more information, visit www.belart.com, or call 800.4BELART.
Scienceware SECADOR Techni-Dome 360 Vacuum Desiccator
According to Bel-Art Products, its new Secador Techni-Dome 360 Vacuum Desiccator is the largest domed desiccator of its kind, offering four times more volume than most other benchtop vacuum desiccators with an overall capacity of 4000 cu. in., 50 cm inner diameter, and clearance for items up to 45 cm tall.
For more information, visit www.belart.com, or call 800.4BELART.
Biohit
Safe-Cone Filters
Now available for the Biohit line of precision pipettors, these tip cone filters prevent contamination of pipettors and samples. Regular use of Safe-Cone filters is intended to prolong the service life of the pipettor by protecting the internal mechanisms. Parts of the pipettors also are protected from vapors and/or liquids.
For more information, visit www.biohit.com, or e-mail
Proline plus Mechanical Pipettors
The ergonomic Proline Plus is fully autoclavable, and available in single-channel, multichannel, and fixed volume models to cover all applications across a wide volume range from 0.1 μL to 10 mL.
For more information, visit www.biohit.com, or e-mail
BioMicro System
MAUI Wash System
According to BioMicro Systems, its all-new MAUI Wash System provides clean, dry microarray slides. The system automates posthybridization wash protocols and is considered ideal for mid-to-high-throughput laboratories that demand high-quality microarray data. The system enables users to control cycle times, reagent usage, temperature, slide agitation, and drying.
For more information, visit www.biomicro.com.
BioTek Instruments
Gen5CL Data Collection and Analysis Software
The Gen5CL Data Collection and Analysis Software is a new software tool for clinical laboratories using the ELx800 and ELx808 microplate readers. According to BioTek, the Gen5CL combines the convenience and security of preprogramed clinical diagnostic assays with the power and flexibility of a PC-based application. The PC-based interface provides greater flexibility in data analysis and output options than on-board microplate reader programs, including LIS system compatibility and data/protocol storage.
Previously programed assays can be easily selected from the database and executed through the Gen5CL interface, custom protocols can be created and stored from the open protocol interface, and multiple user levels can be assigned with customizable permissions for increased security.
For more information, visit www.biotek.com.
Brinkmann Instruments
Bespoke Scientific Glassblowing
Brinkmann Instruments is now able to assist in bespoke scientific glassblowing projects from the design stage through to manufacture. All technical advice and quotations, irrespective of the complexity of design, is given free of charge. The service is based on Brinkmann's partner, Radleys, 40+ years of experience.
For more information, visit www.radleys.co.uk/pages/products/scientific_glassblowing.shtml.
ESA Biosciences
Webinar: Ion Analysis Bringing You Down?
Now available on demand, this Webinar was created to enable chromatographers to gain insight into efficient and cost-effective strategies of ion analysis through HPLC methodologies. The Webinar addresses the concerns that many chromatographers face with ion analysis, and includes presentations and a Q&A session featuring ESA scientist, Dr. Ian Acworth, and industry experts from Synomics Pharmaceutical Services and Johnson & Johnson Pharmaceutical.
For more information, visit www.esainc.com/news/webinars.
Exeter Analytical
Application Note: Analysis of Explosive Compounds
This new application note (TM212) describes a safe and accurate analytical method for accurately determining the percentage nitrogen (N) content of explosive materials such as pentanitrocellulose, dekanitrocellulose, and pyroxylin, using the Model CE440 Elemental Analyzer. Application note TM212 also demonstrates how theoretical values of nitrogen compare closely with data obtained from standard method MIL-STD-286B (T-209.9).
For more information, visit www.exeteranalytical.co.uk/ce440_notes.htm, e-mail
Technical Note: Automated Elemental Analysis of Organic Carbon in Sediment Samples
Technical Note 230 describes how sediment samples are placed in acid to dissolve the inorganic material and then filtered. The filters are then analyzed using an Exeter Analytical Model CE440 CHN elemental analyzer. The optimized Model CE440 methodology uses a combustion method to convert the sample elements in the sediment samples to simple gases (CO2, H2O, and N2). Elements such as halogens and sulfur are removed by scrubbing agents. The resultant gases are homogenized and controlled under exact pressure, temperature, and volume conditions. The homogenized gases are then passed through a known sample volume. This volume of sample gas products is then passed through a series of steady state detectors with CO2 and H2O traps placed between the first two detectors, this enables accurate quantification of the three elements of interest (carbon, hydrogen, and nitrogen).
For more information, visit www.eai1.com, or e-mail
G.E. Healthcare
HiTrap Capto IEX Selection Kit
This set of prepacked HiTrap 1-mL columns is used for selecting the best Capto ion exchange chromatography media for a given application. The kit allows for fast, easy screening of three traditional and two multimodal ion exchange chromatography media before scale-up.
The kit consists of five different high capacity ion exchange and multimodal ion exchange media based on the Capto highly rigid agarose base matrix. After selecting the best chromatography medium for a target protein, larger prepacked columns and bulk media for preparative purification work are available for easy scale-up. Screenings and purifications can be easily performed using a peristaltic pump, or a chromatography system such as ÄKTAdesign.
For more information please visit www.gelifesciences.com/hitrap.
Dextrin Sepharose and StrepTactin Sepharose High-Performance Affinity Chromatography Media
According to G.E. Healthcare, its new, small, evenly sized 34-μm Sepharose high-performance beads ensure that proteins elute in narrow peaks, thus minimizing the need for further concentration steps. The new chromatography media also enable purification under physiological conditions and mild elution, which means that the activity of the target protein is preserved.
Dextrin Sepharose High Performance has been designed for the purification of proteins tagged with maltose binding protein (MBP), and StrepTactin Sepharose High Performance for Strep-tag II fusion proteins.
Both media are available in prepacked 1 and 5 mL MBPTrap HP and StrepTrap HP columns for convenient, fast, and reliable purification. The new media are also easy to pack in, for example, laboratory columns from the Tricorn and XK series when scaling up purifications, and are compatible with commonly used aqueous buffers and easily regenerated using 0.5 M NaOH.
For more information, please visit www.gelifesciences.com/protein-purification.
Genevac
Technical Papers: Concentration of Environmental Samples
In conjunction with several leading laboratories, Genevac has developed a new method that enables environmental samples to be concentrated to less than 1 mL without losing any volatile analytes.
For more information, visit www.genevac.org/en/Technology.asp?S=4&V=1&Page=79.
VirTis Genesis Freeze-Drying System
The compact, free-standing, mobile design of the new Genesis enables the system to be optimally configured to almost any freeze-drying application, and ergonomic profiling allows easy inspection of the vacuum pump and facilitates quick and trouble-free oil changes. For applications where a sterile environment is critical, an easy-to-install clean room version of the Genesis is also available.
The product chamber, shelves, and condenser chamber are made of durable 316L stainless steel, with a squared product chamber that ensures easy cleaning and maximum shelf area. A 4-in. diameter port increases vapor flow from the product to the condenser chamber. Reliable refrigeration systems with proven CFC-free refrigerants allow the Genesis range to achieve a wide range of temperatures enabling freeze-drying of all sample types.
For more information, visit www.genevac.com, e-mail
Benchtop K Series of Freeze Dryers
According to Genevac, its new Benchtop K Series offers fast and efficient freeze-drying, and ease of use that's ensured by one button start-up that activates all operating parameters in the correct sequence. The series, which uses environmentally friendly CFC-free refrigeration systems, are offered in a range of condenser temperatures from −55 to − 105°C to provide the drying power required to freeze dry all aqueous and most organic-based samples.
Condenser sizes range from 3 to 9 L to accommodate a few samples or multiple user applications. A wide selection of accessories allows any shape or size sample container to be processed. The Standard Lyo Control and the optional Automatic Lyo Control systems enable precise pressure (vacuum) control to shorten drying cycles through improved heat transfer. Powerful workstation software provides complete data collection and historical trending of freeze-drying cycles.
For more information, visit www.genevac.com, e-mail
Guava Technologies
CD4 Turnkey Monitoring Package
A complete turnkey package for CD4 monitoring is now available from Guava Technologies. Comprising an optimized, integrated package of reagents, software and instrumentation, the Guava Auto CD4/CD4% System is designed to provide developing countries with a simple, easy-to-use tool to help fight the global AIDS pandemic. By providing values for both CD4 and CD4% of total lymphocytes, the assay is applicable to both adult and pediatric samples. An easy-to-use reagent kit provides CD4 counts, total lymphocyte counts, and CD4% values in one simple assay. The new assay uses a premade cocktail, and only 10 μL of whole blood in a simple two-step, no wash protocol that requires minimal technical expertise to perform.
For more information, visit www.guavatechnologies.com.
Guava Nexin Assay
This new assay is designed to accurately monitor induction and progression of apoptosis quickly and easily by providing all necessary reagent components in a single cocktail to minimize assay steps, assay time, and possible sources of contamination. The assay protocol is identical for use on all Guava Systems, using both tube- and plate-based approaches, and assay-specific Guava Nexin Software automatically calculates results, and offers an easy-to-use interface for additional adjustments. The end result is an assay that easily distinguishes between nonapoptotic cells, early apoptotic cells, late-stage apoptotic, and dead cells as well as nuclear debris.
For more information, visit www.guavatechnologies.com.
Hamilton Robotics
MicroLab Star Venus One
MicroLab VENUS ONE instrument control software for MicroLab STARlet, STAR, and STARplus expands the capabilities of its successful predecessor Vector software. VENUS ONE offers several novel-editing modules for fast
and straightforward programing, Chief among these is the SuperSimpleMethods module, providing users with a five-step setup for common pipetting routines. VENUS ONE also features a new Action Editor, a highly intuitive user interface that provides access to all on-deck actions
For more information, visit www.hamiltonrobotics.com/products/venus.html, e-mail
Hudson Control Group
Hudson SOLO High-Resolution Liquid Dispenser
According to Hudson Control Group, its new SOLO has the added capability of supporting a grouping of multiple syringes (up to 10) with varying bore sizes to support very tiny (<1 μL) to very large (>10 μL) aspirating and dispensing volumes, all on the same unit. With the smallest footprint of any comparable liquid-handling robot, the SOLO can perform DNA transformations, cherry picking, and now hit picking. In addition, the new SOLO has an optional peristaltic pump for high-speed tip washing.
For more information, visit www.hudsoncontrol.com.
LabVantage
SAPPHIRE R5
The SAPPHIRE Release 5 Laboratory Information Management Suite (LIMS) is now available from LabVantage. The SAPPHIRE is a zero footprint, configurable off-the-shelf LIMS that consolidates functionality typically found in multiple laboratory systems. This new release offers ubiquitous global deployment, enhanced user experience, expanded functionality, comprehensive reporting and analytics-driven decision support, and multioptional application server and standard-based services.
For more information, visit www.labvantage.com.
Mettler Toledo
Automated Microbalances
Mettler Toledo now has automated versions of its MX5 microbalance and UMX2 ultra microbalance, for fast and easy precision weighing of small tubular samples. The MX5 Automated-S and the UMX2 Automated-S are considered ideal for applications that include weighing of coatings and checking the thickness of tubular material.
For more information, visit www.mt.com.
XP-K Comparator
According to Mettler Toledo, its new XP-K Comparator Ultra Load line offers a weighing solution with a unique resolution of up to 6 million points for ultra loads. The combination of the new weighing cell and the centering aid ensures perfect performances up to OIML E2 class from 5 to 5000 kg while complying with all regulations even in the highest accuracy classes. The innovative LevelMatic 5000 mechanism eliminates displacement effects and improves the accuracy of weighing results while at the same time reducing loading times.
For more information, visit www.mt.com.
Micronic
Technical Note: Managing Your Compound Library
Entitled ‘Managing your Compound Library,’ this new technical note describes automation products that manage the four stages of sample storage volume measurement: tube decapping, noncontact sample volume measurement, tube capping, and rearraying the tubes.
For more information, visit www.micronic.com, e-mail
Precapped Sample Storage Tubes
Micronic can now provide its sample storage tubes precapped with a wide choice of Thermo Plastic Elastomer (TPE) or Screw caps. All Micronic precapped tubes are manufactured under U.S. Federal standard 209E Class 7 clean room conditions to ensure sterility and cleanliness. USP Class VI-certificated TPE provides a tube seal that is easily pierced, highly chemically resistant, repels water, offers excellent resealing properties, and does not discolor even after long-term exposure to oxygen. Each Micronic TPE cap is made of two components: the cap and a retaining film. This film is easily removed, leaving a high integrity seal on individual tubes.
For more information, visit www.micronic.com, e-mail
Capmat Sealer
According to Micronic, its new Automatic Capmat Sealer caps a full (or partially filled) 96-tube rack in less than 5 s, and is designed to seal all types of sample storage tubes (0.5–1.4 mL).
For more information, visit www.micronic.com, e-mail
Millipore
Laboratory Filtration Product Guide
This new resource is designed to optimize workflows in life science, environmental, clinical, forensic, and industrial research. The first chapter contains a filtration primer to help users understand the principles of membrane filtration, and to select filtration devices to suit particular applications. The Laboratory Filtration Product Guide also features a Chemical Compatibility Chart for all materials used in producing Millipore's filtration products, as well as a Regulated Methods and Applications Guide to help customers quickly locate Millipore products that match membranes or apparatus specified in methods from NIOSH, OSHA, and ASTM.
For more information, visit www.millipore.com.
PureProteome Nickel Magnetic Beads
According to Millipore, this new separation matrix allows the fast and easy purification of polyhistidine-tagged recombinant proteins. Its process for magnetizing porous silica particles provides high-binding capacity, high-affinity beads for efficient protein purification. Unlike many other magnetic beads, PureProteome Nickel Magnetic Beads bind recombinant protein even in the presence of EDTA, a metalion chelator; and offer higher purity while yielding comparable amounts of protein.
For more information, visit www.millipore.com.
Molecular Profiles
Technical Poster: Detection of Low Levels of Amorphous Lactose Using H/D Exchange and FT-Raman Spectroscopy
According to Molecular Profiles, a new method developed from a Knowledge Transfer Partnership with the University of Nottingham and Molecular Profiles, funded by the DTI, demonstrates the use of hydrogen/deuterium (H/D) exchange and FT-Raman spectroscopy for the detection of low levels of amorphous material. The sensitivity of this novel approach is shown to be superior to conventional FT-Raman.
In the application detailed in the poster, amorphous lactose is generated by spray drying a 10% w/v solution using a Buchi minispray drier 190. Deuterium oxide vapor (25% RH) is generated and controlled using a Triton Humidity Generator. Spectra are recorded using a Bruker RFS 100/S FT-Raman spectrometer. Results of the application demonstrate a nondestructive method that is capable of providing reproducible quantitative measurements of low levels of amorphous material in lactose.
For more information, visit www.molprofiles.co.uk, or e-mail
mpanalytics, mpconsulting, and mpformulations Service Platforms
According to Molecular Profiles, its new mpanalytics service platform encompasses analytical service solutions; mpconsulting includes the counsel of the company's pharmaceutical consultants in the areas of lifecycle management and patent and litigation support; and mpformulations addresses the complex challenges in drug delivery.
For more information, visit www.molprofiles.co.uk, e-mail
PANalytical
Training Courses
A new schedule of PANalytical training courses is now available. PANalytical provides both introductory and in-depth training courses covering all areas of X-ray diffraction and X-ray fluorescence spectroscopy. The programs are delivered at PANalytical centers around the world.
For more information, visit www.panalytical.com.
PerkinElmer
Spectrum Express Software
New for the Spectrum 100 and Spectrum One series spectrometers, the new Spectrum Express software is designed to increase efficiency by providing simple, intuitive spectrometer control, data analysis, and reporting. It improves productivity with a process chain feature that allows users to combine a series of data processing steps into a single process command. Once set up, the process chain can be recalled like any single process from the menu. The software also features a COMPARE function that provides simple materials checking by allowing users to compare one spectrum against another or against a directory of spectra. A spectral library search tool assists users with identification of unknown samples.
For more information, visit www.perkinelmer.com/spectrumexpress.
Spectrum 100 Optica FT-IR Spectrometer
According to PerkinElmer, its new Spectrum 100 Optica is the only commercially available Fournier Transform Infrared (FT-IR) spectrometer developed specifically for the optical filters and coatings industry. The instrument provides improved ordinate accuracy for the measurement of optical filters and high refractive index materials. Manufacturers of optical filters and specialty coatings can use the Spectrum 100 Optica to validate the performance specifications of these materials to block or transmit IR radiation. This validation is considered critical in both quality assurance/quality control and research and development of filters and coatings.
For more information, visit www.perkinelmer.com/spectrum100optica.
Porvair Sciences
MicroStream Microplate Thawing Station
The new MicroStream microplate thawing station from Porvair Sciences circulates ambient air across the base of a frozen microplate or tube rack to gently and evenly thaw samples without risk of damage.
For more information, visit www.porvair-sciences.com, e-mail
Low-Volume Disposable Reservoir Trays
A series of low volume 384-well products is now part of Porvair's range of disposable reservoir trays that are designed for use with any liquid-handling system. Molded from high-purity polypropylene, each tray offers high resistance to heat as well as most organic solvents, acids, and bases. With a low-plate profile and a novel pyramid bottom design, Porvair's reservoir trays are designed for easy access to all liquid contents and to ensure a low reagent dead volume for 96- and 384-well filling applications.
For more information, visit www.porvair-sciences.com, e-mail
Gas Permeable Rayon Microplate Sealing Film
According to Porvair Sciences, its new gas permeable rayon microplate sealing film can improve culturing of mammalian cells, bacteria and yeast culture by up to 70% compared to an impermeable seal. Manufactured from high permeability, medical grade rayon, the new heat-sealing film provides a uniform air and CO2 exchange with all microplate wells, unlike plate lids that favor exchange for wells near the plate edges. The breathable membrane also reduces evaporation enhancing longer-term incubation experiments.
For more information, visit www.porvair-sciences.com, e-mail
QIAGEN
EpiTect Product Line Expansion
QIAGEN added five new products to its EpiTect product line, including the EpiTect Whole Bisulfitome Kit, the first kit for amplification of the entire bisulfite-converted genome (bisulfitome); EpiTect MSP Kit, a genetically engineered DNA polymerase for end-point methylation-specific PCR; EpiTect MethyLight PCR Kit for quantitative analysis of methylated DNA using probe-based real-time PCR; EpiTect MethyLight Assay, probe-based real-time assays that enable the standardized quantification and differentiation of methylated and unmethylated DNA for six selected genes related to cancer; and EpiTect Control DNA, a ready-to-use, bisulfite-converted DNA for highly reliable methylation-control experiments.
For more information, visit www.qiagen.com/epigenetics.
Radleys
Carousel 12 Reaction Station
Like its predecessor, the new Carousel 12 Plus Reaction Station has been designed to provide busy chemistry laboratories with an easy-to-use productivity tool that simultaneously heat or cools, stirs, and reflux's up to 12 samples (1–20 mL) under an inert atmosphere.
The Carousel Plus features a new removable reflux and gas distribution head that can be easily transferred, with tubes in situ, between the Carousel's heated-base, cooling reservoir or support stand, providing the user with a uniquely modular system for heated and cooled reactions. The Carousel Plus includes a fluoropolymer insulation plate that sits over the heated base acting as a barrier to heat loss. Studies have shown that the Carousel Plus not only heats up faster, but uses up to 36% less energy to reach the same temperatures as its forerunner. New viewing slots in the heated base provide users with an excellent view of the reaction tubes contents and stirring performance. The circular design of the Carousel Plus allows users to easily rotate the unit, providing access to all tubes without having to lean into the fumehood.
For more information, visit www.radleys.com.
Cool-It Insulated Bowls
Designed to fit on a standard stirring hotplate, a choice of two Cool-It insulated bowls are available to accommodate round bottom flasks from 10 mL to 2 L. Manufactured with a robust, virtually unbreakable, chemically resistant HPDE outer, Cool-It bowls are compatible with a wide range of freezing mixtures enabling cooling of reactions down to −70°C. An insulated foam core maintains low temperatures for long periods, protects users from contact with freezing mixtures, and reduces condensation and ice formation on outer surfaces. To prolong the duration of cooling, Cool-It bowls come with a special lid that reduces the risk of solvent spitting or accidental spilling of reactive reagents into the freezing mixture.
For more information, visit www.radleys.com.
Huber CC-Pilot Controller
Fully compatible with all Huber thermostats, Compatible Control refrigerated circulators, and Unichillers, this new controller offers a universal user interface for precise temperature control from −20 to 400°C.
For more information, visit www.radleys.com.
RheoSense
VROC Viscometer/Rheometer-on-a-Chip
The new VROC Viscometer/Rheometer-on-a-Chip technology from RheoSense enables microliter size samples to be used for high-resolution, accurate, and repeatable viscosity measurement. The small chip geometry extends viscosity measurements beyond conventional instrumentation limits into the realm of very high shear rates. The VROC changes the measurement landscape allowing viscosity characterization at the conditions occurring in actual applications.
For more information, visit www.rheosense.com, or e-mail
RTS Life Science
Technical Paper: Sample Management and Replication
A new poster entitled ‘A New Paradigm in Sample Library Management and Replication’ discusses the RTS Libradexx, an integrated sample library management solution that allows plate management and data tracking, supports both manual and automated storage solutions, and is suitable for all library sizes.
For more information, visit www.rtslifescience.com, or e-mail
Special Optics
High N.A. UV Microscope Objective
Special Opticsrange of UV lenses now includes a high N.A. UV microscope objective with a numerical aperture of 0.90. This high N.A. UV micro objective provides 0.28-μg spot imaging at a wavelength of 248 nm and 0.41-μg spot imaging at a wavelength of 365 nm. The effective focal length is 5.5 mm and the field of view is a 100 μg. It is diffraction limited with less than 0.07 waves RMS wave front distortion over the entire field of view.
For more information, visit www.specialoptics.com.
Telecentric UV Scanning Lenses
Four new telecentric UV scanning lenses are now available from Special Optics to accommodate large input beam diameters of up to 17 mm and wavelengths of 266 or 355 nm. Lens focal lengths include 34, 50 mm, and two at 100 mm with scan fields of 9, 20, 45, and 55 mm, respectively. These new lenses are diffraction limited. They have a deviation from telecentricity of less than 0.9° for single axis scanning and less than 3° for dual axis.
For more information, visit www.specialoptics.com.
Syrris
Atlas Hot and Cold Plate
According to Syrris, its new Atlas Hot and Cold Plate provides an easy and accurate way of heating and cooling reactions in flasks or vials. With an embedded resistance temperature detector to allow feedback ofplate temperature, the Hot and Cold Plate can be accurately controlled from the Atlas Base. By connecting to a recirculating heater/cooler, the plate is able to provide control of a wide temperature range from −40 to + 160°C and the temperature can be fully logged and downloaded to a USB memory stick for offline analysis. Rapid, leak-free connection is made possible with the Atlas Quick Circulator Connectors, and a built-in drip tray collects condensation and melting ice while the chemically resistant aluminum plate provides a wipe clean surface. For high-quality magnetic stirring, the Atlas Magnetic Stirrer module screws directly into the Hot and Cold Plate for easy integration.
For more information, visit www.syrris.com.
TandD Corporation
TR-57U Data Shuttle
The new TR-57U Data Shuttle from TandD is a Handheld Collector with the capacity to collect up to 256,000 readings (16 completely full loggers) from TandD Data Loggers. The TR-57U features a backlit graphical display that allows on-location data analysis and a thumbwheel navigator, and can be programed for Data Range Check and G/NG judgment display. The TR-57U can optically read TandD TR-5S Waterproof Loggers and includes a cable for reading TR-7U loggers. The unit operates with 2 AAA batteries that provide 100 h of operation. An energy-saving Auto Power Off function is provided.
Data can be downloaded to a PC for archive with a Fast USB cable.
For more information, visit www.tandd.com, or e-mail
Thermo Fisher Scientific
Online Metabolomics Resource Center
For metabolomics researchers, this new Web site provides tools and technical advice to help scientists studying small-molecule metabolite profiles. The Metabolomics Solutions Center enables users to tap into Thermo Fisher's knowledge of metabolomics, including new metabolomics application notes, scientific posters, technical guides, Webinars and customer articles from leading researchers within the fields of agriculture, environmental toxicology, disease, nutrition, micro-organisms, lipidomics, and general applications are also available.
The site also features information on integrated solutions for sample preparation, chromatography, mass spectrometry, and analytical software in metabolomics applications. It is customized with the latest metabolomics news and upcoming events, and offers subscriptions to a free metabolomics e-newsletter.
For more information, visit www.thermo.com/metabolomics, e-mail
FLASH 4000 Nitrogen/Protein Analyzer
Designed to offer an alternative to the Kjeldahl methodology for dedicated nitrogen and n/protein analysis in the food and beverage industry, the FLASH 4000 n/protein analyzer features a large-sampled load (2 g), ensuring maximum accuracy and reliability of results and improved productivity capabilities. This solution uses a powerful combustion method for a wide range of applications.
The new FLASH 4000 N/Protein analyzer eliminates the need for sample preparation and is capable of processing more samples than the Kjeldahl method in less than 7 min. In addition, consumable costs associated with the sample preparation are minimized and safety in the laboratory is increased.
For more information, visit www.thermo.com/flash4000, e-mail
ChromQuest 5.0 Software
ChromQuest 5.0 Chromatography Data System software provides a new user interface, data acquisition, data processing, and reporting for Thermo Scientific LC and GC instrumentation, including the Accela High-Speed LC system and all of the configurations of the TriPlus Autosampler. Designed for multiuser and multi-instrument operations, new features include multilevel calibrations, graphic method editing, conditional sequence actions, and automated LIMS export.
For more information, visit www.thermo.com/lc or www.thermo.com/gc, e-mail
Helios Zeta Double- and Single-Beam UV-Visible Spectrophotometers
According to Thermo, these new systems offer unlimited method and data storage using USB memory devices. Integrated local control software provides solutions for a multitude of laboratory requirements from fixed wavelength measurements and quantitative analysis to wavelength scanning and multicomponent analysis. PC control is available from the VISIONsecurity, VISIONlife, and VISIONpro software interfaces. Customized manipulation of data is available using built-in Math functions and the UVcalc spreadsheet feature. Report templates can be created for customized laboratory reporting and documentation of results.
For more information, visit www.thermo.com/uv-vis, or e-mail
TSQ Vantage LC–MS/MS System
According to Thermo, this new LC–MS/MS system delivers up to 10 times more sensitivity than any other triple quadrupole instrument on the market, and does not produce a commensurate increase in noise. In addition, the TSQ Vantage offers unmatched signal-to-noise performance for better reproducibility and precision in the quantitative analysis of small molecules, biomolecules, and peptides.
The TSQ Vantage's new S-Lens ion optics system uses a novel electrostatic field technology to capture virtually every ion and efficiently transfer it into the HyperQuad quadrupole mass analyzer. The S-Lens design is considered a significant advance over high-pressure, skimmer-based ion source designs, as it eliminates mass discrimination and lowers the gas load on the turbo-molecular pumps.
For more information, visit www.thermo.com/tsqvantage, e-mail
Proteome Discoverer
The new Proteome Discoverer proteomics analysis software platform replaces Thermo Scientific BioWorks and enables researchers to combine and compare data from multiple search engines, public databases, and dissociation methods on a larger scale than previously possible, in a program that is easy to use and flexible. Proteome Discoverer's quantitative analysis capabilities include industry-standard best practices, new Thermo Scientific solutions, and isotopic labeling strategies, such as iTRAQ and TMT.
Proteome Discoverer analyzes data from all Thermo Scientific mass spectrometers and is compatible with all standard proteomic workflows. It is backward compatible with results generated using BioWorks, and it offers a seamless upgrade path for current BioWorks users. Proteome Discoverer includes a license to the SEQUEST search algorithm.
For more information, visit www.thermo.com/proteomics, e-mail
Revco Ultima II Cryogenic Freezers
Operating at uniform and stable cryogenic temperatures of −140 and −150°C, these freezers offer a safe and convenient method for the long-term storage of biological materials. According to Thermo, at such low temperatures, metabolic activity is not known to occur, greatly increasing cell viability. As such, these freezers fulfill the requirements of many laboratories, including those of clinical research, life sciences, and pharmaceutical organizations.
Using advanced mechanical refrigeration technology, the freezers offer important advantages over units that rely on liquid nitrogen as a cooling medium. There is greater temperature uniformity throughout the freezer and the interior storage space is maximized, enabling a capacity of up to 21,600 samples. Furthermore, all samples are maintained below the critical temperature of −130°C.
For more information, visit www.thermo.com/mechcryo.
Matrix Hybrid Multichannel Pipette
Ergonomically designed for one-hand pipetting, the Matrix Hybrid Multichannel pipette eliminates strenuous micrometer knob twisting with incremental scrolling, six programmable ‘QUIK-sets’ and a voice recognition system. The 8- and 12-channel pipettes support volume ranges of 0.5–12.5 μL, 2–30 μL, and 20–300 μL.
For more information, visit www.thermofisher.com.
Super-Speed Centrifuge Workflow Solution
Using the new Nalgene 1L super-speed centrifuge bottle, scientists now can spin sample volumes at a higher capacity and at higher speeds than ever before. This super-speed workflow solution provides seamless compatibility between the new Nalgene bottle, FIBERLite carbon fiber rotors, and Thermo Scientific Sorvall Super-speed centrifuges.
For more information, visit www.nalgenelabware.com, or www.thermofisher.com.
Uniqsis
Application Notes: FlowSyn and Drug Discovery Chemistries
A growing collection of application notes by Uniqsis describes some of the drug discovery chemistries to which the FlowSyn Continuous Flow Reactor has been applied, including reaction scale-up and optimization, and a comparison with batch microwave chemistries.
For more information, visit www.uniqsis.com, or e-mail
FlowSyn Continuous Flow Reactor
Reactions on the FlowSyn Continuous Flow Reactor can now be carried out at up to 260°C and pressures up to 1000 psi (∼70 Bar), making high-activation energy chemistries, which may previously have required a catalyst or use of a microwave reactor, potential candidates for continuous flow synthesis. Other improvements include easier pump priming and refinements to the automated reaction control so that the user can control the amount of the pre- and postplug dispersion phases collected with the steady-state reaction product.
For more information, visit www.uniqsis.com, or e-mail
Velocity11
Technical Note: Automating the Analysis of Cell Viability
A new technical note describes how a combination of the Velocity11 Bravo liquid handler, BenchCel plate handling system, and the CellTiter-Glo kit from Promega can automate the analysis of cell viability. Using the described protocol up to 65 plates can be run without user intervention. The typical throughput for the described setup was found to be about 3 h for 50 plates, depending on exact protocol and liquid-handling steps.
Plates are delivered to the Bravo, reagent is added, and plates are placed on shaking devices. The reagent is added without tip touching, therefore, only one tip box is needed for the total run. The plates are transported back to the BenchCel for room temperature incubation, directly followed by signal detection on a microplate reader. The automated workstation ensures that all process and incubation times are accurately managed, to ensure reliable and repeatable results.
For more information, visit www.velocity11.com.
Technical Note: Automated Workstations for Bulk Reagent and Cell Dispensing Applications
An automated Bulk Reagent and Cell Plating Workstation can be created using existing dispensers or a new dispenser purchased through Velocity11. An optional second dispenser integrated with the BenchCel Workstation can further increase dispensing throughput from 70 to up to 130 microplates/h.
For more information, visit www.velocity11.com/files/File/07BulkBCwkstnHprint.pdf.
Technical Poster: Fully Integrated Compound Repository and Management System
A new technical poster from Velocity11 describes a high-throughput plate and tube sample-processing system installed at the Eskitis Institute for Cell and Molecular Therapies, Griffith University, Brisbane, Australia. The poster describes the technical, logistical, and intellectual property challenges overcome in establishing the fully integrated compound repository and management system. Using the Velocity11 BioCel automation system, the Eskitis Institute set up an environmentally controlled plate and tube processing system where compound integrity is maintained without compromising flexibility.
For more information, visit www.velocity11.com/files/File/P012.pdf, or call +44.1438.712428 or +1.650.846.6609.
2008 Users Group Meeting
The 2008 Velocity11 User Group meeting will be held in Barcelona, Spain, November 4–7, 2008, and will offer a comprehensive program of workshops, roundtable discussions, and talks covering current topics in lab automation. In addition, attendees will be able to preview new applications and product combinations from Agilent and Velocity11.
For more information, e-mail
BenchCel R Platform
According to Velocity11, its all-new BenchCel R Platform can handle more integrations, rack styles, types of labware, and capacity options than any other compact automated workstation. Features including the ability to integrate more instruments per side; the flexibility to work with lidded microplates, deep-well plates, and tip boxes; and a choice of two-, four-, or six-rack configurations enable the BenchCel R Platform to productively handle more applications.
The BenchCel R Platform is an integrated benchtop robot and microplate storage solution that delivers the speed and precision of a full-sized automation platform. It features a high-speed plate shuttle that accesses integrated microplate stacks and peripheral microplate-based instruments including liquid handlers, dispensers, readers, sealers, washers, centrifuges, microplate storage devices, and more with a customizable, modular design.
For more information and a free copy of the Workstation Configuration Handbook, visit www.velocity11.com, e-mail
Viscotek
RImax GPC/SEC System
The RImax Gel Permeation/Size Exclusion Chromatography (GPC/SEC) system is, according to Viscotek, a new tool for the conventional characterization of natural and synthetic polymers, copolymers, proteins, nanoparticles, and other macromolecules. Combining the GPCmax fully integrated pump, autosampler, and degasser module, Model 3580 Refractive Index (RI) detector and OmniSEC GPC/SEC software, the RImax offers all the attributes of a high-performance Conventional GPC system.
For more information, visit www.viscotek.com, e-mail
More News
Accelerated Technology Laboratories (ATL) promoted Fred Rider to the position of director of support services. Mr. Rider worked at ATL for 10 years, previously serving as ATL's quality assurance manager and senior software engineer.
Adept Technology received multiple orders for its Adept Quattro s650 robots from customers in the Asia-pacific region. The high-speed robots were sold into packaging applications in Japan and Korea and represent the company's first sales into the world's largest and fourth largest (respectively) robotics markets, according to market statistics from the International Federation of Robotics.
The Adept Quattro robot was selected by SLS Solar Line Saxony (SLS) as part of its standard products for its automation equipment for solar cell production. SLS was established as a joint venture between Germany's Roth & Rau and USK Karl Utz Sondermaschinen to accelerate the production of standard technology products for the manufacturer of solar cells.
Formerly part of Barloworld Scientific, Sterilin Limited is a newly formed independent business, specializing in the manufacture of single-use laboratory plastics, including Sterilin single-use plastics; Iwaki tissue culture products; Sterilin Silicone Devices (formerly Esco Silicone Rubber); and Sterilin Packaging Products (formerly Azlon Packaging).
BioTek Instruments was awarded the LanthaScreen-Certified Plus designation from Invitrogen. The designation ensures that BioTek's Synergy 4 and Synergy 2 multimode microplate readers are validated to strict standards in instrument setup and assay performance.
Evotec successfully completed its merger with Renovis, making Renovis a wholly owned subsidiary of Evotec.
FEI Company selected Shimadzu to sell FEI systems to its established base of customers in Japan.
HighRes Biosolutions announced plans to open an office in the United Kingdom, not far from Manchester airport. The U.K. office will provide dedicated support for all systems and standalone products, and offer a complete suite of all HighRes Biosolutions products to enable customer training. There will also be a testing and validation facility, and the office will hold spares for customers and sell consumables.
HighRes Biosolutions signed a major contract to supply the Burnham Institute for Medical Research with specialized three-pod system equipment for storing and screening large biological libraries.
IDBS Founder and CEO Neil Kipling was awarded an honorary doctorate (DUniv) from the University of Surrey, and IDBS was honored with the 2008 Frost & Sullivan European Bioinformatics Service Differentiation Innovation Award.
Invitrogen and BioTek Instruments entered into a collaboration agreement to validate the compatibility of Invitrogen's reagents and technology platforms with BioTek's microplate detection instruments.
Lab901 Limited of Loanhead, Edinburgh, United Kingdom, raised £3.55 million in its latest equity-funding round. The financing syndicate was led by new investor, Alliance Trust Equity Partners, together with existing investors, Scottish Enterprise's Scottish Venture Fund, Archangel Informal Investment Ltd., and Noble VCT plc.
Microbac Laboratories selected LabCORE to automate business processes and laboratory document management at facilities in Wilson, NC and Louisville, KY.
NextGen Group expanded its protein biomarker team with the appointments of Dr. Ruth VanBogelen as director of biomarkers and proteomics, and Dr. M. Walid Qoronfleh as vice president of business development.
PerkinElmer Life and Analytical Sciences began direct distribution of its instrumentation and extended its suite of services, including its portfolio of OneSource solutions, in the Republic of Ireland and Northern Ireland. The new PerkinElmer subsidiary, PerkinElmer Ireland, assumed direct responsibility for instrumentation sales, service, and support for more than 250 customers in Ireland from its distributor, Foss Ireland.
Lynda A. Merrill joined Qiagen as vice president of molecular diagnostic sales for Europe, Middle East, Africa, and Australia (EMEAA). She is based in the U.K. office, and reports to Phillip Sefton, vice president of EMEAA Commercial Operations.
RTS Life Science was honored with the IET North West Innovation in Engineering Award from the Institute of Engineering and Technology for the RTS Automated Blood Fractionation 500 system.
Syngene installed its first Dyversity 6 2D gel imaging system at the new Singapore Massachusetts Institute of Technology Alliance for Research and Technology Center, and that scientists at East Tennessee State University detected proteins associated with cytotoxic effects of Vitamin E on prostate cancer cells using Dymension, Syngene's 2D gel image-analysis software.
www.TechTransferOnline.com is now available free of charge to all nonprofit (tax-exempt) organizations that wish to list their IP on the Web site, which features thousands of technologies available for licensing. All of the site's features continue to be included at no charge, including automated scraping of existing Web sites, uploading of database files, listing of confidential IPs, attachment of additional files, and visibility to viewers.
Thermo Fisher Scientific established a new partnership with Alta Tecnología that allows the company to support sales activities in Chile, Paraguay, Uruguay, and Bolivia for the Thermo Scientific portfolio of informatics products.
The 1000th purchase of the Thermo Scientific iCAP 6000 Series of ICP emission spectrometers was made by the Plansee Group in Austria to perform R&D and quality control analyses of specialized metal alloys.
HUNT Biobank selected the Thermo Scientific Nautilus LIMS to gather, store, manage, track, and retrieve the biological data of approximately 100,000 people from Nord-Trøndelag County, Norway, as part of one of the largest population-based health studies ever performed.
Dr. Alexander Makarov, Thermo Fisher Scientific's director of global research for Life Sciences Mass Spectrometry, received the 2008 Distinguished Contribution in Mass Spectrometry Award from the American Society for Mass Spectrometry.
Call for Papers
Win an Apple MacBook Air
All JALA manuscript submissions received before
Poster Abstracts Still Being Accepted
ALA is still accepting poster abstracts for LabAutomation2009, and all submitted abstracts are eligible to win an Apple MacBook Air in a random drawing. For details, visit www.labautomation.org/LA09.