Despite two recent trials of the role of early radiotherapy following radical prostatectomy, there remains no consensus as to best practice and clinicians tend to base their decisions around MDT discussion and pathological risk factors. This paper develops the argument for international Intergroup trial, RADICALS-RT, which is now recruiting, and which is our opportunity to resolve this important issue.
BollaMvan PoppelHColletteLvan CanghPVekemansKDa PozzoLPostoperative radiotherapy after radical prostatectomy: a randomised controlled trial (EORTC trial 22911). Lancet2005;366(August (9485)):572–8.
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ThompsonIMTangenCMParadeloJLuciaMSMillerGTroyerDAdjuvant radiotherapy for pathological T3N0M0 prostate cancer significantly reduces risk of metastases and improves survival: long-term followup of a randomized clinical trial. The Journal of Urology2009;181(March (3)):956–62.
