Low-dose radiation epidemiological studies: An assessment of methodological problems

Abrahamson S. (1990). Childhood leukaemia at Sellafield—A Genetically Transmitted Mutational Disease. RERF Update, Spring 1990, pp. 3–4.

Albert R. E. Omran A. R. (1968). Follow-up study of patients treated by X-ray epilation for tinea capitis. I. Population characteristics, post-treatment illnesses, and mortality experience. Arch. Environ. Health 17, 899–918.

Archer V. E. (1987). Association of nuclear fallout with leukemia in the United States. Arch. Environ. Health 42, 263–271.

Archer V. E. Saccomanno G. S. Jones J. H. (1974). Frequency of different histologic types of bronchogenic carcinoma as related to radiation exposure. Cancer 34, 2056–2060.

Axelson O. Anderson K. Desai G. Fagerlund I. Jansson B. Karlsson C. Wingren G. (1988). Indoor radon exposure and active and passive smoking in relation to the occurrence of lung cancer. Scand. J. Work Environ. Health 14, 286–292.

Beck H. L. Krey P. W. (1983). Radiation exposure in Utah from Nevada nuclear tests. Science 220, 18–24.

Beebe G. W. (1981). The atomic bomb survivors and the problem of low-dose radiation effects. Am. J. Epidemiol. 114, 761–783.

Beral V. (1990). Leukaemia and nuclear installations. Brit. Med. J. 300, 411–412.

Beral V. Inskip H. Fraser P. Booth M. Coleman D. Rose G. (1985). Mortality of employees of the United Kingdom Atomic Energy Authority, 1946–1979. Brit. Med. J. Clin. Res. 291, 440–447.

Beral V. Fraser P. Carpenter L. Booth M. Brown A. Rose G. (1988). Mortality of employees of the Atomic Weapons Establishment, 1951–82. Brit. Med. J. 297, 757–770.

Biberman R. Tal Y. Neeman E. Lusky A. Modan B. (1990). Radon exposure measurements of non-smoking lung-cancer patients. Transactions. Joint Meeting 1990 of The Nuclear Societies of Israel. Vol. 16. Herzliya.

Bithell J. F. Stiller C. A. (1988). A new calculation of the carcinogenic risk of obstetric X-raying. Stat. Med. 7, 857–864.

Black D. (1987). New evidence on childhood leukaemia and nuclear establishments. Brit. Med. J. 294, 591–592.

Boice J. D. Jr. Blettner M. Kleinerman R. A. Stovall M. Moloney W. C. Engholm G. Austin D. F. Bosch A. Cookfair D. L. Krementz E. T. (1987). Radiation dose and leukemia risk in patients treated for cancer of the cervix. J. Natl. Cancer Inst. 79, 1295–1311.

Bross I. D. Bross N. S. (1987). Do atomic veterans have excess cancer? Am. J. Epidemiol. 126, 1042–1050.

Bross I. D. Natarajan N. (1972). Leukemia from low-level radiation: identification of susceptible children. N. Engl. J. Med. 287, 107–110.

Burch P. R. (1981). Radiation hazards. Brit. J. Radiol. 54, 697–698.

Caldwell G. G. Kelley D. Zack M. Falk H. Heath C.W. Jr. (1980). Leukemia among participants in military maneuvers at a nuclear bomb test: A preliminary report. JAMA 244, 1575–1578.

Caldwell G. G. Kelley D. Zack M. Falk H. Heath C. W. Jr (1983). Mortality and cancer frequency among military nuclear test (Smoky) participants, 1957 through 1979. JAMA 250, 620–624.

Checkoway H. Mathew R. M. Shy C. M. Watson J. E. Jr. Tankersley W. G. Wolf S. H. Smith J. C. Fry S. A. (1985). Radiation, work experience, and cause specific mortality among workers at an energy research laboratory. Br. J. Ind. Med. 42, 523–533.

Checkoway H. Pearce N. Crawford-Brown D. J. Cragle D. L. (1988). Radiation doses and cause specific mortality among workers at a nuclear materials fabrication plant. Am. J. Epidemiol. 127, 255–266.

Clapp R. W. Cobb S. Chan C. K. Walker B. Jr. (1987). Leukemia near Massachusetts nuclear power plant. Lancet 2, 1324–1325.

Clarke R. H. Southwood R. E. (1989). Risks from ionizing radiation. Nature 338, 197–198.

Cook-Mozaffari P. J. Ashwood F. L. Vincent T. Forman D. Alderson M. (1987). Cancer Incidence and Mortality in the Vicinity of Nuclear Installations England and Wales 1959–60. Office of Population Censuses and Surveys.

Cook-Mozaffari P. J. Darby S. C. Doll R. Forman D. Hermon C. Pike M. C. Vincent T. (1989a). Geographical variation in mortality from leukaemia and other cancers in England and Wales in relation to proximity to nuclear installations, 1969–78. Brit. J. Cancer 59, 476–485.

Cook-Mozaffari P. Darby S. Doll R. (1989b). Cancer near potential sites of nuclear installations. Lancet 2, 1145–1147.

Court Brown W. M. Doll R. Bradford Hill A. (1960). Incidence of leukaemia after exposure to diagnostic radiation in utero Br. Med. J. 5212, 1539–1545.

Crump K. S. Ng T. H. Cuddihy R. G. (1987). Cancer incidence patterns in the Denver metropolitan area in relation to the Rocky Flats plant. Am. J. Epidemiol. 126, 127–135.

Darby S. C. Doll R. (1987). Fallout, radiation doses near Dounreay, and childhood leukaemia. Brit. Med. J. 294, 603–607.

Darby S. C. Nakashima E. Kato H. (1985). A parallel analysis of cancer mortality among atomic bomb survivors and patients with ankylosing spondylitis given x-ray therapy. J. Natl. Cancer Inst. 75, 1–21.

Darby S. C. Doll R. Gill S. K. Smith P. G. (1987). Long term mortality after a single treatment course with X-rays in patients treated for ankylosing spondylitis. Brit. J. Cancer 55, 179–190.

Darby S. C. Kendall G. M. Fell T. P. O'Hagan J. A. Muirhead C. R. Ennis J. R. Ball A. M. Dennis J. A. Doll R. (1988). A summary of mortality and incidence of cancer in men from the United Kingdom who participated in the United Kingdom's atmospheric nuclear weapon tests and experimental programmes. Brit. Med. J. 296, 332–338.

Diamond E. L. Schmerler H. Lilienfeld A. M. (1973). The relationship of intra-uterine radiation to subsequent mortality and development of leukemia in children. Am. J. Epidemiol. 97, 283–313.

Dunster H. J. (1990). Review needed of risks. Nature 344, 98.

Enstrom J. E. (1983). Cancer mortality patterns around the San Onofre nuclear power plant, 1960–1978. Am. J. Public Health 73, 83–92.

Frigerio N. A. Stowe R. S. (1976). Carcinogenic and genetic hazard from background radiation. In: Biological and Environmental Effects of Low-Level Radiation, pp. 385–393. International Atomic Energy, Vienna.

Gardner M. J. Hall A. J. Downes S. Terrell J. D. (1987a). Follow up study of children born elsewhere but attending schools in Seascale, West Cumbria (schools cohort). Brit. Med. J. Clin. Res. 295, 819–822.

Gardner M. J. Hall A. J. Downes S. Terrell J. D. (1987b). Follow up study of children born to mothers resident in Seascale, West Cumbria (birth cohort). Brit. Med. J. Clin. Res. 295, 822–827.

Gardner M. J. Hall A. J. Snee M. P. Downes S. Powell C. A. Terrell J. D. (1990a). Methods and basic data of case-control study of leukaemia and lymphoma among young people near Sellafield nuclear plant in West Cumbria. Brit. Med. J. 300, 429–434.

Gardner M. J. Snee M. P. Hall A. J. Powell C. A. Downes S. Terrell J. D. (1990b). Results of case-control study of leukaemia and lymphoma among young people near Sellafield nuclear plant in West Cumbria. Brit. Med. J. 300, 423–429.

Gibson R. Bross I. D. J. Graham S. (1968). Leukemia in children exposed to multiple risk factors. New Engl. J. Med. 279, 906–909.

Gibson R. Graham S. Lilienfeld A. M. (1972). Irradiation in the epidemiology of leukemia among adults. J. Natl. Cancer Inst. 48, 301–311.

Gilbert E. S. Marks S. (1979). An analysis of the mortality of workers in a nuclear facility. Radiat. Res. 79, 122–148.

Gilbert E. S. Petersen G. R. Buchanan J. A. (1989). Mortality of workers at the Hanford Site: 1945–1981. Health Phys. 56, 11–25.

Gilman E. A. Kneale G. W. Knox E. G. Stewart A. M. (1988). Pregnancy x-rays and childhood cancers: effects of exposure age and radiation dose. J. Radiol. Prot. 8, 3–8.

Graham S. Levin M. L. Lilienfeld A. M. Schuman L. M. Gibson R. Down J. E. Hempelmann L. (1966). Preconception, intrauterine, and postnatal irradiation as related to leukemia. Natl. Cancer Inst. Monogr. 19, 347–371.

Harvey E. B. Boice J. D. Honeyman M. Jr. Flannery J. T. (1985). Prenatal x-ray exposure and childhood cancer in twins. N. Engl. J. Med. 312, 541–545.

Hildreth N. G. Shore R. E. Dvoretsky P. M. (1989). The risk of breast cancer after irradiation of the thymus in infancy. N. Engl. J. Med. 321, 1281–1284.

Holm L. E. Wiklund K. E. Lundell G. E. Bergman N. A. Bjelkengren G. Ericsson U. B. Cederquist E. S. Lidberg M. E. Lindberg R. S. Wicklund H. V. (1989). Cancer risk in population examined with diagnostic doses of ¹³¹I. J. Natl. Cancer Inst. 81, 302–306.

Hopton P. A. McKinney P. A. Cartwright R. A. Mann J. R. Birch J. M. Hartley A. L. Waterhouse J. A. Johnston H. E. Draper G. J. Stiller C. A. (1985). X-rays in pregnancy and the risk of childhood cancer. Lancet 2, 773.

Hrubec Z. Boice J. D. Monson R. R. Jr. Rosenstein M. (1989). Breast cancer after multiple chest fluoroscopies: second follow up of Massachusetts women with tuberculosis. Cancer Res. 49, 229–234.

Hutchinson G. B. MacMahon B. Jablon S. Land C. E. (1979). Review of report by Mancuso, Stewart and Kneale of radiation exposure of Hanford workers. Health Phys. 37, 207–220.

Jablon S. (1987). Re: Do atomic veterans have excess cancer? New results correcting for the healthy soldier bias. Am. J. Epidemiol. 126, 1214.

Jablon S. Kato H. (1970). Childhood cancer in relation to prenatal exposure to atomic-bomb radiation. Lancet 2, 1000–1003.

Jablon S. Hrubec Z. Boice J. D. Jr. Stone B. J. (1990). Cancer in populations living near nuclear facilities. NIH Publication No. 90–874.

Jacobson A. P. Plato P. A. Frigerio N. A. (1976). The role of natural radiations in human leukemogenesis. Am. J. Pub. Health 66, 31–37.

Johnson C. J. (1984). Cancer incidence in an area of radioactive fallout downwind from the Nevada test site. JAMA 251, 230–236.

Johnson C. J. (1987). A cohort study of cancer incidence in Mormon families exposed to nuclear fallout versus an area-based study of cancer deaths in whites in southwestern Utah. Am. J. Epidemiol. 125, 166–168.

Jones R. R. (1984). Discharges from Sellafield. Lancet 2, 744.

Kinlen L. (1988). Evidence for an infective cause of childhood leukaemia: comparison of a Scottish new town with nuclear reprocessing sites in Britain. Lancet 2, 1323–1327.

Klotz J. B. Petix J. R. Zagraniski R. T. (1989). Mortality of a residential cohort exposed to radon from industrially contaminated soil. Am. J. Epidemiol. 129, 1179–1186.

Knox E. G. Stewart A. M. Kneale G. W. Gilman E. A. (1987). Prenatal irradiation and childhood cancer. J. Soc. Radiol. Prot. 7, 177–189.

Knox E. G. Stewart A. M. Gilman E. A. Kneale G. W. (1988). Background radiation and childhood cancers. J. Radiol. Prot. 8, 9–18.

Land C. E. (1980). Estimating cancer risks from low doses of ionizing radiation. Science 209, 1197–1203.

Land C. E. McKay F. W. Machado S. G. (1984). Childhood leukemia and fallout from the Nevada nuclear tests. Science 223, 139–144.

Lees R. E. Steele R. Roberts J. H. (1987). A case control study of lung cancer relative to domestic radon exposure. Int. J. Epidemiol. 16, 7–12.

Lubin J. H. Qiao Y. L. Taylor P. R. Yao S. X. Schatzkin A. Mao B. L. Rao J. Y. Xuan X. Z. Li J. Y. (1990). Quantitative evaluation of the radon and lung cancer association in a case control study of Chinese tin miners. Cancer Res. 50, 174–180.

Lyon J. L. Klauber M. R. Gardner J. W. Udall K. S. (1979). Childhood leukemias associated with fallout from nuclear testing. N. Engl. J. Med. 300, 397–402.

Machado S. G. Land C. E. McKay F. W. (1987). Cancer mortality and radioactive fallout in southwestern Utah. Am. J. Epidemiol. 125, 44–61.

MacMahon B. (1962). Prenatal X-ray exposure and childhood cancer. J. Natl. Cancer Inst. 28, 1173–1191.

Mancuso T. F. Stewart A. Kneale G. (1977). Radiation exposures of Hanford workers dying from cancer and other causes. Health Phys. 33, 369–385.

Modan B. Baidatz D. Mart H. Steinitz R. Levin S. G. (1974). Radiation-induced head and neck tumours. Lancet 1, 277–279.

Modan B. Chetrit A. Alfandary E. Katz L. (1989). Increased risk of breast cancer after low-dose irradiation. Lancet 1, 629–631.

Mole R. H. (1974). Antenatal irradiation and childhood cancer: Causation or coincidence. Brit. J. Cancer 30, 199–208.

Mole R. H. (1990). Childhood cancer after prenatal exposure to diagnostic X-ray examinations in Britain. Brit. J. Cancer 62, 152–168.

Monson R. R. MacMahon B. (1984). Prenatal x ray exposure and cancer in children. In: Radiation Carcinogenesis: Epidemiology and Biological Significance, pp. 97–106 ( Boice J. D. Jr. Fraumeni J. F. Jr. , eds). Raven Press, New York.

Morrison H. I. Semenciw R. M. Mao Y. Wigle D. (1988). Cancer mortality among a group of Fluorspar miners exposed to radon progeny. Am. J. Epidemiol. 128, 1266–1275.

Najarian T. Colton T. (1978). Mortality from leukemia and cancer in shipyard workers. Lancet 1, 1018–1020.

Oppenheim B. E. Griem M. L. Meier P. (1974). The effects of low-dose prenatal irradiation in humans: Analysis of Chicago lying-in data and comparison with other studies. Radiat. Res. 57, 508–544.

Peterson G. R. Gilbert E. S. Buchanan J. A. Stevens R. G. (1990). A case-cohort study of lung cancer, ionizing radiation, and tobacco smoking among males at the Hanford site. Health Phys. 58, 3–11.

Pierce D. A. (1989). An Overview of the Cancer Mortality Data on the Atomic Bomb Survivors. International Conference on Risk Assessment of Energy Development and Modern Technology, Kyoto, 1988. RERF CR 1–89.

Pochin E. E. (1988). Difficulties in estimating the effect of low radiation doses in man. J. Radiol. Prot. 8, 163.

Preston D. L. Pierce D. A. (1988). The effect of changes in dosimetry on cancer mortality risk estimates in the atomic bomb survivors. Radiat. Res. 114, 437–466.

Preston-Martin S. Thomas D. C. Yu M. C. Henderson B. E. (1989). Diagnostic radiography as a risk factor for chronic myeloid and monocytic leukaemia (CML). Brit. J. Cancer 59, 639–644.

Raman S. Dulberg C. S. Spasoff R. A. Scott T. (1987). Mortality among Canadian military personnel exposed to low-dose radiation. Can. Med. Assoc. J. 136, 1051–1056.

Rinsky R. A. Zumwalde R. D. Waxweiler R. J. Murray W.E. Jr. Bierbaum P. J. Landrigan P. J. Terpilak M. Cox C. (1981). Cancer mortality at a naval nuclear shipyard. Lancet 1, 231–235.

Robinette C. D. Jablon S. (1983). Studies of participants at tests and of nuclear weapons: I. The Plumbob series. In: Somatic and Genetic Effects ( Broerse J. J. Barendsen G. W. Kal H. B. van der Kogel A. J. , eds). Proceedings of the Seventh International Congress of Radiation Research. Martinus Nijhoff Publishers C8–13, Amsterdam.

Roman E. Beral V. Carpenter L. Watson A. Barton C. Ryder H. Aston D. L. (1987). Childhood leukaemia in the West Berkshire and Basingstoke and North Hampshire District Health Authorities in relation to nuclear establishments in the vicinity. Brit. Med. J. 294, 597–602.

Ron E. Modan B. Preston D. Alfandary E. Stovall M. Boice J.D. Jr. (1989). Thyroid neoplasia following low-dose radiation in childhood. Radiat. Res. 120, 516–531.

Roscoe R. J. Steeland K. Halperin W. E. Beamont J. J. Waxweiler R. J. (1989). Lung cancer mortality among non-smoking uranium miners exposed to radon daughters. JAMA 262, 629–633.

Rotblat J. (1977). The puzzle of absent effects. New Scientist 75, 475.

Samet J. M. (1989). Radon and lung cancer. J. Natl. Cancer Inst. 81, 745–757.

Samet J. M. Nero A.V. Jr. (1988). Indoor radon and lung cancer. N. Engl. J. Med. 320, 591–593.

Samet J. M. Patlak D. R. Morgan M. V. Marbury M. C. (1989). Radon progeny exposure and lung cancer risk in New Mexico U miners. A case-control study. Health Phys. 56, 415–421.

Schoenberg J. B. Klotz J. B. Wilcox H. B. Nicholls G. P. Gil-del-Real M. T. Steinhagen A. Mason T. J. (1990). A case-control study of residential radon and lung cancer among New Jersey women. Cancer Res. 50, 6520–6524.

Sevc J. Kunz E. Tomasek L. Placek V. Horacek J. (1988). Cancer in man after exposure to Rn daughters. Health Phys. 54, 27–46.

Shimizu Y. Kato H. Schull W. J. Preston D. L. Fujita S. Pierce D. A. (1989). Studies of the mortality of A-bomb survivors. 9. Mortality, 1950–1985. Part 1. Comparison of risk coefficients for site-specific cancer mortality based on the DS86 and T65DR shielded kerma and organ doses. Radiat. Res. 118, 502–524.

Shimizu Y. Schull W. J. Kato H. (1990a). Epidemiological Studies at RERF. Paper in Proceedings of a Workshop on Risk Estimates for Radiation Carcinogenesis, Munstereifel, Germany.

Shimizu Y. Schull W. J. Kato H. (1990b). Cancer risk among atomic bomb survivors. The RERF Life Span Study. JAMA 264, 601–604.

Shiono P. H. Chung C. S. Myrianthopoulos N. C. (1980). Preconception radiation, intrauterine diagnostic radiation, and childhood neoplasia. J. Natl. Cancer Inst. 65, 681–686.

Smith P. G. Douglas A. J. (1986). Mortality of workers at the Sellafield plant of British Nuclear Fuels. Brit. Med. J. 293, 845–854.

Stern F. B. Waxweiler R. A. Beaumont J. J. Lee S. T. Rinsky R. A. Zumwalde R. D. Halperin W. E. Bierbaum P. J. Landrigan P. J. Murray W. E. (1986). A case-control study of leukemia at a naval nuclear shipyard. Am. J. Epidemiol. 123, 980–992.

Stewart A. M. Kneale G. W. (1970). Radiation dose effects in relation to obstetric X-rays and childhood cancer. Lancet 1, 1185–1188.

Stewart A. Webb J. Hewitt D. (1956). Malignant disease in childhood and diagnostic irradiation in utero Lancet 2, 447.

Svensson C. Eklund G. Pershagen G. (1987). Indoor exposure to radon from the ground and bronchial cancer in women. Int. Arch. Occup. Environ. Health 59, 123–131.

Svensson C. Pershagen G. Klominek J. (1989). Lung cancer in women and type of dwelling in relation to radon exposure. Cancer Res. 49, 1861–1865.

Tao Z. Wei L. (1986). An epidemiological investigation of mutational diseases in the high background radiation area of Yangjiang, China. J. Radiat. Res. 27, 141–150.

Tolley H. D. Marks S. Buchanan J. A. Gilbert E. S. (1983). A further update of the analysis of mortality of workers in a nuclear facility. Radiat. Res. 95, 211–213.

Totter J. R. MacPherson H. G. (1981). Do childhood cancers result from prenatal x-rays? Health Phys. 40, 511–524.

Wei L. Zha Y. Tao Z. Weihui He Chen D. Yuan Y. (1988). Recent Advances of Health Survey in High Background Radiation Areas in Yangjiang, China, pp. 1–17.

Wei L. Zha Y. Tao Z. Weihui He Chen D. Yuan Y. (1990). Epidemiological investigation of radiological effects in high background radiation areas of Yangjiang, China. J. Radiat. Res. 31, 119–136.

Yoshimoto Y. Kato H. Schull W. J. (1988). Risk of cancer among children exposed in utero to A-bomb radiations, 1950–84. Lancet 2, 665–669.