Multiple palmar xanthomas may often be seen first by the hand surgeon. One such case presented to us in the hand clinic. Further investigations revealed the presence of a more sinister metabolic problem of type III hyperlipoproteinemia. We discuss the details of this case and review relevant literature on the subject.
HsuJCSuTCChenMFLiauCSLeeYT. Xanthoma striatum palmare in a patient with primary biliary cirrhosis and hypercholesterolemia. J Gastroenterol Hepatol.2005;20(11):1799–800.
2.
HuCHEllefsonRDWinkelmannRK. Lipid synthesis in cutaneous xanthoma. J Invest Dermatol.1982;79(2):80–5.
3.
ManchandaYSharmaVK. Intertriginous xanthomas: a marker of homozygous type IIa hyperlipoproteinemia. Int J Dermatol.2004;43(9):676–7.
4.
MoyleMTateB. Homozygous familial hypercholesterolaemia presenting with cutaneous xanthomas: response to liver transplantation. Australas J Dermatol.2004;45(4):226–8.
5.
NagarajanDVBorehamPAParfittVJ. Palmar striated xanthomas. Postgrad Med J.2003;79(938):690.
6.
Sato-MatsumuraKCMatsumuraTYokoshikiHChibaHShimizuH. Xanthoma striatum palmare as an early sign of familial type III hyperlipoproteinemia with an apoprotein E genotype epsilon2/epsilon2. Clin Exp Dermatol.2003;28(3):321–2.
