We describe the clinical presentation and pathological features of an unusual case of tracheal agenesis. The axial derivatives of the primitive foregut between the larynx and stomach were represented by a single structure featuring sequential segmentation into regions showing exclusively tracheal or esophageal differentiation in a pattern that is not easily classified by existing nosologic systems nor explained by the conventional hypothesis of dysontogenesis.
FaroRS, GoodwinCD, OrganCHJr., Tracheal agenesis. Ann Thorac Surg1979;28:295–299.
2.
FloydJ, CampbellDC, DominyDE. Agenesis of the trachea. Am Rev Respir Dis1962;86:557–560.
3.
BremerJL. Congenital Anomalies of the Viscera; Their Embryological Basis. Cambridge MA: Harvard University Press, 1957.
4.
SmithIE. The early development of the trachea and esophagus in relation to atresia of the esophagus and tracheoesophageal fistula. Contrib Embryol1957;36:41–57.
BogueCW, LouLJ, VasavadaH, WilsonCM, JacobsHC. Expression of Hoxb genes in the developing mouse foregut and lung. Am J Respir Cell Mol Biol1996;15:163–171.
