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Research article

First published 2021-3

Probability intervals of toxicity and efficacy design for dose-finding clinical trials in oncology

Xiaolei Lin, Yuan Ji

Statistical Methods in Medical Research

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Research article

First published 2024-4

BOIN-ETC: A Bayesian optimal interval design considering efficacy and toxicity to identify the optimal dose combinations

Tomoyuki Kakizume, Kentaro Takeda, Masataka Taguri [...]

Statistical Methods in Medical Research

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Research article

First published 2013-6

Early phase trial design for assessing several dose levels for toxicity and efficacy for targeted agents

Antje Hoering, Alan Mitchell, Michael LeBlanc [...]

Clinical Trials

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Research article

First published 2019-12

Sequential or combined designs for Phase I/II clinical trials? A simulation study

Caroline Rossoni, Aurélie Bardet, Birgit Geoerger [...]

Clinical Trials

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Research article

First published 2024-6

Dose optimization for cancer treatments with considerations for late-onset toxicities

Lucie Biard, Anaïs Andrillon, Rebecca B Silva [...]

Clinical Trials

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Research article

First published 2014-2

A Bayesian adaptive Phase I–II clinical trial for evaluating efficacy and toxicity with delayed outcomes

Joseph S Koopmeiners, Jaime Modiano

Clinical Trials

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Research article

First published 2025-6

Dose selection criteria to identify the optimal dose based on ranked efficacy-toxicity outcomes without reliance on clinical utilities

Sydney Porter, Anne Eaton, Thomas A Murray

Statistical Methods in Medical Research

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Research article

First published 2017-11

Dose Finding in Late-Phase Drug Development

Lei Nie, Kyung Y. Lee, Nicole Verdun [...]

Therapeutic Innovation & Regulatory Science

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Research article

First published 1999-01

Tumor Models: Assessing Toxicity in Efficacy Studies

Lawrence H. Arp

Toxicologic Pathology

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Research article

First published 2014-12

Effective sample size for computing prior hyperparameters in Bayesian phase I–II dose-finding

Peter F Thall, Richard C Herrick, Hoang Q Nguyen [...]

Clinical Trials

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