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Research article

First published 2012-2-20

Bispecific Tandem Single Chain Antibody Simultaneously Inhibits β-Secretase and Promotes α-Secretase Processing of AβPP

Shanta Boddapati, Yona Levites, Vick Suryadi [...]

Journal of Alzheimer’s Disease

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Review article

First published 2021-05-04

Selective Secretase Targeting for Alzheimer’s Disease Therapy

Alvaro Miranda, Enrique Montiel, Henning Ulrich [...]

Journal of Alzheimer’s Disease

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Review article

First published 2011-6-14

The Many Substrates of Presenilin/γ-Secretase

Annakaisa Haapasalo, Dora M. Kovacs

Journal of Alzheimer’s Disease

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Research article

First published 2010-10-1

Caveolin-1 Regulates γ-Secretase-Mediated AβPP Processing by Modulating Spatial Distribution of γ-Secretase in Membrane

Arun Kapoor, Wen-Ming Hsu, Bo-Jeng Wang [...]

Journal of Alzheimer’s Disease

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Review article

First published 2012-9-11

γ-Secretase Modulator in Alzheimer's Disease: Shifting the End

Weiming Xia, Stephen T. Wong, Eugene Hanlon [...]

Journal of Alzheimer’s Disease

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Research article

First published

γ-Secretase Modulators and Inhibitors Induce Different Conformational Changes of Presenilin 1 Revealed by FLIM and FRET

Xin Wang, Jin Cui, Wei Li [...]

Journal of Alzheimer’s Disease

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Research article

First published 2014-7-16

Acetylcholinesterase Modulates Presenilin-1 Levels and γ-Secretase Activity

Maria-Letizia Campanari, María-Salud García-Ayllón, Olivia Belbin [...]

Journal of Alzheimer’s Disease

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Review article

First published 2009

γ-Secretase Catalyzes Sequential Cleavages of the AβPP Transmembrane Domain

Xuemin Xu

Journal of Alzheimer’s Disease

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Research article

First published 2013-7-9

The Development of an in vivo γ-Secretase Assay using Zebrafish Embryos

Lachlan Wilson, Michael Lardelli

Journal of Alzheimer’s Disease

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Research article

First published 2016-4-12

Inhibition of Cholesterol Biosynthesis Reduces γ -Secretase Activity and Amyloid-β Generation

Yoonhee Kim, Chaeyoung Kim, Hye Young Jang [...]

Journal of Alzheimer’s Disease

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