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Research article

First published 2018-3-27

Generation and Partial Characterization of Rabbit Monoclonal Antibody to Pyroglutamate Amyloid-β 3-42 (pE 3 -Aβ)

Pankaj D. Mehta, Bruce A. Patrick, Marc Barshatzky [...]

Journal of Alzheimer’s Disease

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Research article

First published 2015-1-6

I716F AβPP Mutation Associates with the Deposition of Oligomeric Pyroglutamate Amyloid-β and α-Synucleinopathy with Lewy Bodies

Evelyn Sieczkowski, Ivan Milenkovic, Vivek Venkataramani [...]

Journal of Alzheimer’s Disease

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Research article

First published 2012-3-30

Intracellular Amyloid-β Accumulation in Calcium-Binding Protein-Deficient Neurons Leads to Amyloid-β Plaque Formation in Animal Model of Alzheimer's Disease

Minho Moon, Hyun-Seok Hong, Dong Woo Nam [...]

Journal of Alzheimer’s Disease

Open access

Research article

First published 2014-1-24

Glutaminyl Cyclase in Human Cortex: Correlation with (pGlu)-Amyloid-β Load and Cognitive Decline in Alzheimer's Disease

Markus Morawski, Stephan Schilling, Moritz Kreuzberger [...]

Journal of Alzheimer’s Disease

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Research article

First published 2013-5-21

Oligomeric Pyroglutamate Amyloid-β is Present in Microglia and a Subfraction of Vessels in Patients with Alzheimer's Disease: Implications for Immunotherapy

Oliver Wirths, Antje Hillmann, Laurent Pradier [...]

Journal of Alzheimer’s Disease

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Research article

First published 2015-3-18

Neuron Loss and Behavioral Deficits in the TBA42 Mouse Model Expressing N-Truncated Pyroglutamate Amyloid-β 3–42

Julius N. Meißner, Yvonne Bouter, Thomas A. Bayer

Journal of Alzheimer’s Disease

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Research article

First published 2012-2-20

Detection of Peri-Synaptic Amyloid-β Pyroglutamate Aggregates in Early Stages of Alzheimer's Disease and in AβPP Transgenic Mice Using a Novel Monoclonal Antibody

Markus Mandler, Edward Rockenstein, Kiren Ubhi [...]

Journal of Alzheimer’s Disease

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Research article

First published 2014-6-4

Brain Pyroglutamate Amyloid-β is Produced by Cathepsin B and is Reduced by the Cysteine Protease Inhibitor E64d,Representing a Potential Alzheimer's Disease Therapeutic

Gregory Hook, Jin Yu, Thomas Toneff [...]

Journal of Alzheimer’s Disease

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Review article

First published 2014-12-2

Inhibition of Glutaminyl Cyclase Ameliorates Amyloid Pathology in an Animal Model of Alzheimer's Disease via the Modulation of γ-Secretase Activity

Hyundong Song, Yu Jin Chang, Minho Moon [...]

Journal of Alzheimer’s Disease

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Research article

First published 2014-1-24

Identification of N-Terminally Truncated Pyroglutamate Amyloid-β in Cholesterol-Enriched Diet-Fed Rabbit and AD Brain

Roxanna Perez-Garmendia, Luis Fernando Hernandez-Zimbron, Miguel Angel Morales [...]

Journal of Alzheimer’s Disease

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