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Research article

First published 1992-1

Two Procedures for the Prediction of Acute Toxicity (LD50) from Cytotoxicity Data

Willi Halle, Horst Spielmann

Alternatives to Laboratory Animals

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Research article

First published 1992-1

Hepatocytes in Primary Culture: An Alternative to LD50 Testing? Validation of a Predictive Model by Multivariate Analysis

Anne-Françoise Peloux, Christian Fédérici, Nicole Bichet [...]

Alternatives to Laboratory Animals

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Research article

First published 2003-3

The Registry of Cytotoxicity: Toxicity Testing in Cell Cultures to Predict Acute Toxicity (LD50) and to Reduce Testing in Animals 1

Willi Halle, Marlies Halder, Andrew Worth [...]

Alternatives to Laboratory Animals

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Research article

First published 1989-12

Cytotoxicity Evaluation of the First Ten MEIC Chemicals: Acute Lethal Toxicity in Man Predicted by Cytotoxicity in Five Cellular Assays and by Oral LD50 Tests in Rodents

Björn Ekwall, Inger Bondesson, José V. Castell [...]

Alternatives to Laboratory Animals

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Research article

First published 2005-2

Lack of Predictivity of the Rat Lethality (LD50) Test for Ecological and Human Health Effects

Herbert S. Rosenkranz, Albert R. Cunningham

Alternatives to Laboratory Animals

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Other

First published 2015-7

Non-animal Replacements for Acute Toxicity Testing

Carol Barker-Treasure, Kevin Coll, Nathalie Belot [...]

Alternatives to Laboratory Animals

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Research article

First published 1999-11

Determination of the Starting dose for Acute Oral Toxicity (LD50) Testing in the up and down Procedure (UDP) from Cytotoxicity Data

Horst Spielmann, Elke Genschow, Manfred Liebsch [...]

Alternatives to Laboratory Animals

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Research article

First published 2007-8

Prediction of Acute Toxicity in HPCT-1E3 Hepatocytoma Cells with Liver-like Transport Activities

Carsten Kneuer, Cathleen Lakoma, Walther Honscha

Alternatives to Laboratory Animals

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Research article

First published 2008-5

The Intercostal NMJ Assay — A New Alternative to the Conventional LD50 Assay for the Determination of the Therapeutic Potency of Botulinum Toxin Preparations

Alexander Huber, Richard M. France, Lisa Riccalton-Banks [...]

Alternatives to Laboratory Animals

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Other

First published 2016-7

Exploring Waiving Opportunities for Mammalian Acute Systemic Toxicity Tests

Rabea Graepel, David Asturiol, Pilar Prieto [...]

Alternatives to Laboratory Animals

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