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1-10 of 2110 results for phase 3 design

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Select article: Comparison of adaptive seamless Phase 2/3 designs for dose selection in clinical trials with multiple endpoints

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Research article

First published 2025-8

Comparison of adaptive seamless Phase 2/3 designs for dose selection in clinical trials with multiple endpoints

Man Jin

Clinical Trials

Select article: Simulation-guided phase 3 trial design to evaluate vaccine effectiveness to prevent Ebola virus disease infection: Statistical considerations,design rationale,and challenges

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Research article

First published 2016-2

Simulation-guided phase 3 trial design to evaluate vaccine effectiveness to prevent Ebola virus disease infection: Statistical considerations,design rationale,and challenges

An Vandebosch, Robin Mogg, Nele Goeyvaerts [...]

Clinical Trials

Select article: Phase 1 Trial Design: Is 3 + 3 the Best?

Free access

Research article

First published 2014-7

Phase 1 Trial Design: Is 3 + 3 the Best?

Aaron R. Hansen, Donna M. Graham, Gregory R. Pond [...]

Cancer Control

Select article: An adaptive seamless Phase 2-3 design with multiple endpoints

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Research article

First published 2021-4

An adaptive seamless Phase 2-3 design with multiple endpoints

Man Jin, Pingye Zhang

Statistical Methods in Medical Research

Select article: Clinical trial design in phase 2 and 3 trials for pulmonary hypertension

Open access

Research article

First published 2020-10

Clinical trial design in phase 2 and 3 trials for pulmonary hypertension

Sylvia Nikkho, Peter Fernandes, R. James White

Pulmonary Circulation

Select article: A New Clinical Trial Design Combining Phases 2 and 3: Sequential Designs with Treatment Selection and a Change of Endpoint

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Other

First published 2005-4

A New Clinical Trial Design Combining Phases 2 and 3: Sequential Designs with Treatment Selection and a Change of Endpoint

Susan Todd, Nigel Stallard

Therapeutic Innovation & Regulatory Science

Select article: Probability-of-decision interval 3+3 (POD-i3+3) design for phase I dose finding trials with late-onset toxicity

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Research article

First published 2022-3

Probability-of-decision interval 3+3 (POD-i3+3) design for phase I dose finding trials with late-onset toxicity

Zichun Xu, Xiaolei Lin

Statistical Methods in Medical Research

Select article: A likelihood-based approach for computing the operating characteristics of the 3+3 phase I clinical trial design with extensions to other A+B designs

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Research article

First published 2015-2

A likelihood-based approach for computing the operating characteristics of the 3+3 phase I clinical trial design with extensions to other A+B designs

Cody Chiuzan, Elizabeth Garrett-Mayer, Sharon D Yeatts

Clinical Trials

Select article: From Adaptive Design to Modern Protocol Design for Drug Development: Part II. Success Probabilities and Effect Estimates for Phase 3 Development Programs

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Other

First published 2010-5

From Adaptive Design to Modern Protocol Design for Drug Development: Part II. Success Probabilities and Effect Estimates for Phase 3 Development Programs

Frank Brefz, Sue-Jane Wang

Therapeutic Innovation & Regulatory Science

Select article: An Adaptive,Dose-Finding,Seamless Phase 2/3 Study of a Long-Acting Glucagon-like Peptide-1 Analog (Dulaglutide): Trial Design and Baseline Characteristics

Free access

Meeting report

First published 2012-11

An Adaptive,Dose-Finding,Seamless Phase 2/3 Study of a Long-Acting Glucagon-like Peptide-1 Analog (Dulaglutide): Trial Design and Baseline Characteristics

Mary Jane Geiger, Zachary Skrivanek, Brenda Gaydos [...]

Journal of Diabetes Science and Technology

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