Sage Journals: Discover world-class research

Retricted access

Research article

First published 2007-7

Improving the Decision to Pursue a Phase 3 Clinical Trial by Adjusting for Patient-Specific Factors in Evaluating Phase 2 Treatment Efficacy Data

Glenn Heller, Michael W. Kattan, Howard I. Scher

Medical Decision Making

Retricted access

Other

First published 2010-7

Design Archetypes for Phase 2 Clinical Trials in Central Nervous System Disorders

Craig H. Mallinckrodt, Michael J. Detke, William R. Prucka [...]

Therapeutic Innovation & Regulatory Science

Open access

Review article

First published 2024-12

Selecting Informative Patients for Phase 2 Progressive Trials in MS: Design Considerations for Phase 2 Clinical Trials in Progressive MS

Marcus W. Koch, Carlos Camara-Lemarroy, Eva Strijbis [...]

Multiple Sclerosis Journal

Open access

Research article

First published 2020-10

Clinical trial design in phase 2 and 3 trials for pulmonary hypertension

Sylvia Nikkho, Peter Fernandes, R. James White

Pulmonary Circulation

Retricted access

Research article

First published 2008-9

Implementation of a Phase 1 Adaptive Clinical Trial in a Treatment of Type 2 Diabetes

Fabián S. Tibaldi, Benoit H. L. Beck, Alun Bedding

Therapeutic Innovation & Regulatory Science

Retricted access

Review article

First published 2011-11

Platelet Aggregation Quality Control in a Multicenter,Phase 2 Clinical Trial

James McRedmond

Therapeutic Innovation & Regulatory Science

Retricted access

Other

First published 2005-4

A New Clinical Trial Design Combining Phases 2 and 3: Sequential Designs with Treatment Selection and a Change of Endpoint

Susan Todd, Nigel Stallard

Therapeutic Innovation & Regulatory Science

Retricted access

Research article

First published 2025-8

Comparison of adaptive seamless Phase 2/3 designs for dose selection in clinical trials with multiple endpoints

Man Jin

Clinical Trials

Retricted access

Research article

First published 2025-6

Evaluating the impact of stratification on the power and cross-arm balance of randomized phase 2 clinical trials

Anna Moseley, Michael LeBlanc, Boris Freidlin [...]

Clinical Trials

Retricted access

Research article

First published 2001-05

Interleukin 2 Gene Therapy for Prostate Cancer: Phase I Clinical Trial and Basic Biology

Arie Belldegrun, Cho-Lea Tso, Amnon Zisman [...]

Human Gene Therapy

Search results