Search results: Sage Journals

Restricted accessResearch articleFirst published December, 2018

Multiple daytime administration of the selective orexin-2 receptor antagonist JNJ-42847922 induces somnolence in healthy subjects without residual central effects

Peter D van der Ark, Georg Golor, Luc van Nueten [...]

Journal of Psychopharmacology

Restricted accessResearch articleFirst published February, 2019

The selective orexin-2 receptor antagonist seltorexant improves sleep: An exploratory double-blind,placebo controlled,crossover study in antidepressant-treated major depressive disorder patients with persistent insomnia

Sander Brooks, Gabriël E Jacobs, Peter de Boer [...]

Journal of Psychopharmacology

Open accessResearch articleFirst published March, 2018

Orexin-A protects SH-SY5Y cells against H 2 O 2 -induced oxidative damage via the PI3K/MEK 1/2 /ERK 1/2 signaling pathway

Chun-Mei Wang, Chun-Qing Yang, Bao-Hua Cheng [...]

International Journal of Immunopathology and Pharmacology

Open accessResearch articleFirst published September, 2024

A male-specific mechanism of meningeal nociceptor sensitization promoting migraine headache

Caroline M. Kopruszinski, Grace Lee, Laurent K. Martin [...]

Cephalalgia

Restricted accessResearch articleFirst published June, 2018

A randomized Phase 2 study to evaluate the orexin-2 receptor antagonist seltorexant in individuals with insomnia without psychiatric comorbidity

Peter De Boer, Wayne C Drevets, Hany Rofael [...]

Journal of Psychopharmacology

Open accessReview articleFirst published 2017

A review of orexin’s unprecedented potential as a novel,highly-specific treatment for various localized and metastatic cancers

Nicole L Graybill, Volkmar Weissig

Sage Open Medicine

Restricted accessResearch articleFirst published April, 2017

Orexin-A Protects Human Neuroblastoma SH-SY5Y Cells Against 6-Hydroxydopamine-Induced Neurotoxicity: Involvement of PKC and PI3K Signaling Pathways

Hamzeh Pasban-Aliabadi, Saeed Esmaeili-Mahani, Mehdi Abbasnejad

Rejuvenation Research

Restricted accessOtherFirst published September, 2008

Changes in brain orexin levels in a rat model of depression induced by neonatal administration of clomipramine

P. Feng, D. Vurbic, Z. Wu [...]

Journal of Psychopharmacology

Restricted accessResearch articleFirst published July, 2012

Controlled Cortical Impact Traumatic Brain Injury Acutely Disrupts Wakefulness and Extracellular Orexin Dynamics as Determined by Intracerebral Microdialysis in Mice

Jon T. Willie, Miranda M. Lim, Rachel E. Bennett [...]

Journal of Neurotrauma

Restricted accessResearch articleFirst published August, 2017

Effects of Restraint Stress on Lipopolysaccharide-Induced Reactions of Orexinergic System

E.A. Korneva, S.V. Perekrest, K.Z. Shainidze [...]

Advances in Neuroimmune Biology

Restricted accessResearch articleFirst published December, 2018

Multiple daytime administration of the selective orexin-2 receptor antagonist JNJ-42847922 induces somnolence in healthy subjects without residual central effects

Peter D van der Ark, Georg Golor, Luc van Nueten [...]

Journal of Psychopharmacology

Restricted accessResearch articleFirst published February, 2019

The selective orexin-2 receptor antagonist seltorexant improves sleep: An exploratory double-blind,placebo controlled,crossover study in antidepressant-treated major depressive disorder patients with persistent insomnia

Sander Brooks, Gabriël E Jacobs, Peter de Boer [...]

Journal of Psychopharmacology

Open accessResearch articleFirst published March, 2018

Orexin-A protects SH-SY5Y cells against H 2 O 2 -induced oxidative damage via the PI3K/MEK 1/2 /ERK 1/2 signaling pathway

Chun-Mei Wang, Chun-Qing Yang, Bao-Hua Cheng [...]

International Journal of Immunopathology and Pharmacology

Open accessResearch articleFirst published September, 2024

A male-specific mechanism of meningeal nociceptor sensitization promoting migraine headache

Caroline M. Kopruszinski, Grace Lee, Laurent K. Martin [...]

Cephalalgia

Restricted accessResearch articleFirst published June, 2018

A randomized Phase 2 study to evaluate the orexin-2 receptor antagonist seltorexant in individuals with insomnia without psychiatric comorbidity

Peter De Boer, Wayne C Drevets, Hany Rofael [...]

Journal of Psychopharmacology

Open accessReview articleFirst published 2017

A review of orexin’s unprecedented potential as a novel,highly-specific treatment for various localized and metastatic cancers

Nicole L Graybill, Volkmar Weissig

Sage Open Medicine

Restricted accessResearch articleFirst published April, 2017

Orexin-A Protects Human Neuroblastoma SH-SY5Y Cells Against 6-Hydroxydopamine-Induced Neurotoxicity: Involvement of PKC and PI3K Signaling Pathways

Hamzeh Pasban-Aliabadi, Saeed Esmaeili-Mahani, Mehdi Abbasnejad

Rejuvenation Research

Restricted accessOtherFirst published September, 2008

Changes in brain orexin levels in a rat model of depression induced by neonatal administration of clomipramine

P. Feng, D. Vurbic, Z. Wu [...]

Journal of Psychopharmacology

Restricted accessResearch articleFirst published July, 2012

Controlled Cortical Impact Traumatic Brain Injury Acutely Disrupts Wakefulness and Extracellular Orexin Dynamics as Determined by Intracerebral Microdialysis in Mice

Jon T. Willie, Miranda M. Lim, Rachel E. Bennett [...]

Journal of Neurotrauma

Restricted accessResearch articleFirst published August, 2017

Effects of Restraint Stress on Lipopolysaccharide-Induced Reactions of Orexinergic System

E.A. Korneva, S.V. Perekrest, K.Z. Shainidze [...]

Advances in Neuroimmune Biology