Sage Journals: Discover world-class research

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Research article

First published 2001-11

A Genetically Engineered Cell-based System for Detecting Metabolism-mediated Toxicity

Sarah Bull, Ingrid Langezaal, Richard Clothier [...]

Alternatives to Laboratory Animals

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Research article

First published 1999-1

A Preliminary Comparison of LiverBeads™ with a Conventional Rat Hepatocyte Culture Preparation: Some Aspects of Xenobiotic Metabolism and Related Toxicity

Alison H. Hammond, Michael J. Garle, Jeffrey R. Fry

Alternatives to Laboratory Animals

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Research article

First published 1992-12

Correction of Purine Nucleoside Phosphorylase Deficiency by Retroviral-Mediated Gene Transfer in Mouse S49 T Cell Lymphoma: A Model for Gene Therapy of T Cell Immunodeficiency

Mark D. Foresman, David M. Nelson, R. Scott McIvor

Human Gene Therapy

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Research article

First published 2002-12

Metabolism and Neurotoxicity: The Significance of Genetically Engineered Cell Lines and New Three-Dimensional Cell Cultures

Sandra Coecke, Chantra Eskes, Joanne Gartion [...]

Alternatives to Laboratory Animals

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Research article

First published 1992-4

Toxicity of Glycols and Allyl Alcohol Evaluated by Means of Co-cultures of Microcarrier-attached Rat Hepatocytes and BALB/C 3T3 Mouse Fibroblasts

Jens-Uwe Voss, Hasso Seibert

Alternatives to Laboratory Animals

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Research article

First published 2007-03

Glycemic Control of Apoptosis in the Pancreatic Beta Cell: Danger of Extremes?

Geert A. Martens, Mark Van de Casteele

Antioxidants & Redox Signaling

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Research article

First published 1988-09

Metabolic Activation of Carcinogens and Toxic Chemicals

D.V. Parke, C. Ioannides, D.F.V. Lewis

Human & Experimental Toxicology

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Research article

First published 2002-10

A New Bioassay Including a Small Scale Hepatocyte Bioreactor for Hepato-Mediated Toxicity Testing in a Target Cell Line

C.J. Deglmann, R. Metzger, M. Stickel [...]

The International Journal of Artificial Organs

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Research article

First published 1990-11

In Vitro Models to Study Mechanisms of Lung Toxicity

Åke Ryrfeldt, Ian A. Cotgreave, Peter Moldéus

Alternatives to Laboratory Animals

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Research article

First published 2001-5

The Use of Cultured Hepatocytes to Investigate the Metabolism of Drugs and Mechanisms of Drug Hepatotoxicity

Maria J. Gómez-Lechón, Xavier Ponsoda, Roque Bort [...]

Alternatives to Laboratory Animals

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