Sage Journals: Discover world-class research

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Research article

First published 2026

Response-adaptive randomization with imperfect intermediate endpoints

Yousra Kherabi, Michael A Proschan, Lori E Dodd

Clinical Trials

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Other

First published 2007-10

The intermediate endpoint effect in logistic and probit regression

D.P. MacKinnon, C.M. Lockwood, C.H. Brown [...]

Clinical Trials

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Other

First published 2008-02

Interim futility analysis with intermediate endpoints

Bryan Goldman, Michael LeBlanc, John Crowley

Clinical Trials

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Research article

First published 2021-4

An adaptive seamless Phase 2-3 design with multiple endpoints

Man Jin, Pingye Zhang

Statistical Methods in Medical Research

Free access

Other

First published 1999-11

Colonic Mucosal Aberrant Crypt Foci: Are They Useful Intermediate Endpoints for Predicting and Understanding the Development of Colonic Mucosal Neoplasia?

Laurence O. Whiteley

Toxicologic Pathology

Retricted access

Research article

First published 2024-10

Using multistate models with clinical trial data for a deeper understanding of complex disease processes

Terry M Therneau, Fang-Shu Ou

Clinical Trials

Free access

Research article

First published 2007-5

Quantitative science methods for biomarker validation in chemoprevention trials

Laurence Freedman

Cancer Biomarkers

Open access

Review article

First published 2021

Surrogate endpoints for early-stage breast cancer: a review of the state of the art,controversies,and future prospects

María Gion, José Manuel Pérez-García, Antonio Llombart-Cussac [...]

Therapeutic Advances in Medical Oncology

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Research article

First published 2020-6

Risk stratification in normotensive acute pulmonary embolism patients: focus on the intermediate–high risk subgroup

Ana Rita Santos, Pedro Freitas, Jorge Ferreira [...]

European Heart Journal: Acute Cardiovascular Care

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Research article

First published 2012-8

Critical appraisal of trials for validation of ‘risk-guided’ cardiovascular disease prevention therapy

Almudena Castro, Sandra O Rosillo, Angeles Alonso [...]

European Journal of Preventive Cardiology

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