Sage Journals: Discover world-class research

Open access

Review article

First published 2026-2

The clinical phenotype of carriers of intermediate alleles in the huntingtin gene: A scoping review

Anna van Hofslot, Mayke Oosterloo, Joost J.A. de Jong [...]

Journal of Huntington's Disease

Retricted access

Research article

First published

Is There Convincing Evidence that Intermediate Repeats in the HTT Gene Cause Huntington’s Disease?

Mayke Oosterloo, Martine J. Van Belzen, Emilia K. Bijlsma [...]

Journal of Huntington's Disease

Open access

Review article

First published 2018

Transcriptional Regulation of the Huntingtin Gene

Sarah B. Thomson, Blair R. Leavitt

Journal of Huntington's Disease

Open access

Research article

First published 2021-12

Oligonucleotides Targeting DNA Repeats Downregulate Huntingtin Gene Expression in Huntington's Patient-Derived Neural Model System

Tea Umek, Thomas Olsson, Olof Gissberg [...]

Nucleic Acid Therapeutics

Retricted access

Other

First published 2011-4

Gene Therapy in Mouse Models of Huntington Disease

Amber L. Southwell, Paul H. Patterson

The Neuroscientist

Open access

Research article

First published 2023-04

Chemical Modifications and Design Influence the Potency of Huntingtin Anti-Gene Oligonucleotides

Osama Saher, Eman M. Zaghloul, Tea Umek [...]

Nucleic Acid Therapeutics

Open access

Review article

First published 2019-4

Silencing of the Mutant Huntingtin Gene through CRISPR-Cas9 Improves the Mitochondrial Biomarkers in an In Vitro Model of Huntington’s Disease

Gary L. Dunbar, Sindhuja Koneru, Nivya Kolli [...]

Cell Transplantation

Retricted access

Research article

First published 2018-04

Whole-Brain Connectivity in a Large Study of Huntington's Disease Gene Mutation Carriers and Healthy Controls

Flor A. Espinoza, Jessica A. Turner, Victor M. Vergara [...]

Brain Connectivity

Open access

Research article

First published 2022-01

Efficient and Precise Processing of the Optimized Primary Artificial MicroRNA in a Huntingtin-Lowering Adeno-Associated Viral Gene Therapy In Vitro and in Mice and Nonhuman Primates

Wei Wang, Pengcheng Zhou, Xin Wang [...]

Human Gene Therapy

Retricted access

News

First published 2022-01

Gene Therapy for Huntington's Disease: The Future Is in Gene Editing

Ana Rita Batista

Human Gene Therapy

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