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Research article

First published 2005-01

Electrophysiological safety of DW-286a,a novel fluoroquinolone antibiotic agent

Eun-Joo Kim, Ki-Suk Kim, Won-Ho Shin

Human & Experimental Toxicology

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Research article

First published 2010-12

Using Electrophysiology and In Silico Three-Dimensional Modeling to Reduce Human Ether-à-go-go Related Gene K + Channel Inhibition in a Histamine H3 Receptor Antagonist Program

Adam J. Davenport, Clemens Möller, Alexander Heifetz [...]

ASSAY and Drug Development Technologies

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Research article

First published 2010-12

A Pharmacologically Validated,High-Capacity,Functional Thallium Flux Assay for the Human Ether-à-go-go Related Gene Potassium Channel

William A. Schmalhofer, Andrew M. Swensen, Brande S. Thomas [...]

ASSAY and Drug Development Technologies

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Research article

First published 2010-12

Identification of Human Ether-à-go-go Related Gene Modulators by Three Screening Platforms in an Academic Drug-Discovery Setting

Xi-Ping Huang, Thomas Mangano, Sandy Hufeisen [...]

ASSAY and Drug Development Technologies

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Research article

First published 2013-12

Halide Ion Effects on Human Ether-à-go-go Related Gene Potassium Channel Properties

Haoyu Zeng, Bharathi Balasubramanian, Jacob R. Penniman [...]

ASSAY and Drug Development Technologies

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Research article

First published 2010-12

Comparison of Human Ether-à-go-go Related Gene Screening Assays Based on IonWorks Quattro and Thallium Flux

Terry R. Bridal, Michael Margulis, Xin Wang [...]

ASSAY and Drug Development Technologies

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Research article

First published 2022-5

Investigational New Drug Enabling Nonclinical Safety Pharmacology Assessment of the Iminosugar UV-4,a Broad-Spectrum Host-Targeted Antiviral Agent

Jeffry Shearer, Gary Wolfe, Aruna Sampath [...]

International Journal of Toxicology

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Research article

First published 2011-12

hERGCentral: A Large Database to Store,Retrieve,and Analyze Compound-Human Ether-à-go-go Related Gene Channel Interactions to Facilitate Cardiotoxicity Assessment in Drug Development

Fang Du, Haibo Yu, Beiyan Zou [...]

ASSAY and Drug Development Technologies

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Research article

First published 2010-12

Profiling Diverse Compounds by Flux- and Electrophysiology-Based Primary Screens for Inhibition of Human Ether-à-go-go Related Gene Potassium Channels

Beiyan Zou, Haibo Yu, Joseph J. Babcock [...]

ASSAY and Drug Development Technologies

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Other

First published 2006-7

Estimation of Proarrhythmic Hazards by QT Prolongation/Shortening: QT Obsession?

Luc M. Hondeghem

Therapeutic Innovation & Regulatory Science

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