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Research article

First published 2023-6

A model-based approach for historical borrowing,with an application to neovascular age-related macular degeneration

Francesco Brizzi, Bernhard Steiert, Herbert Pang [...]

Statistical Methods in Medical Research

Open access

Review article

First published 2025

From past to future: Digital approaches to success of clinical drug trials for Parkinson's disease

Cen Cong, Madison Milne-Ives, Ananya Ananthakrishnan [...]

Journal of Parkinson’s Disease

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Research article

First published 2013-11

Coalition Against Major Diseases

Diane Stephenson, Enrique Aviles, Lisa J. Bain [...]

Therapeutic Innovation & Regulatory Science

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Meeting report

First published 2019-11

The 18th FRAME Annual Lecture,October 2019: Human In Silico Trials in Pharmacology

Blanca Rodriguez

Alternatives to Laboratory Animals

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Research article

First published 1994-7

Decision Analytic Modeling: Some Uses in the Evaluation of New Pharmaceuticals

Henry Glick, Bruce Kinosian, Kevin Schulman

Therapeutic Innovation & Regulatory Science

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Research article

First published 2013-1-21

Chronic Administration of Dimebon Ameliorates Pathology in Tau P301S Transgenic Mice

Owen M. Peters, Natalie Connor-Robson, Vladimir B. Sokolov [...]

Journal of Alzheimer’s Disease

Open access

Research article

First published 2017-7-29

Of Mice and Men: Comparative Analysis of Neuro-Inflammatory Mechanisms in Human and Mouse Using Cause-and-Effect Models

Alpha Tom Kodamullil, Anandhi Iyappan, Reagon Karki [...]

Journal of Alzheimer’s Disease

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Research article

First published 1995-10

Modeling with Clinical Trial Data: Moving from the Data Researchers Have to the Data Decision Makers Need

Kit N. Simpson

Therapeutic Innovation & Regulatory Science

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Research article

First published 2019-03-29

Can We Prevent Dementia and Not Prevent Neurons from Dying?

Robert E. Becker, Nigel H. Greig

Journal of Alzheimer’s Disease

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Research article

First published 2016-11

Stratification,Hypothesis Testing,and Clinical Trial Simulation in Pediatric Drug Development

Ann W. McMahon, Kevin Watt, Jian Wang [...]

Therapeutic Innovation & Regulatory Science

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