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Articles (1135)

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1-10 of 1135 results for dose-limiting toxicity

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Select article: Suitability of the Limit Dose in Evaluating Reproductive Toxicity of Substances and Preparations

Free access

Research article

First published 2007-5

Suitability of the Limit Dose in Evaluating Reproductive Toxicity of Substances and Preparations

Klaus Schneider, Jan Oltmanns, Rainer Van Gelder [...]

International Journal of Toxicology

Select article: Impact of the Charlson Comorbidity Index on dose-limiting toxicity and survival in locally advanced and metastatic renal cell carcinoma patients treated with first-line sunitinib or pazopanib

Retricted access

Research article

First published 2020-7

Impact of the Charlson Comorbidity Index on dose-limiting toxicity and survival in locally advanced and metastatic renal cell carcinoma patients treated with first-line sunitinib or pazopanib

Nazım C Demircan, Özkan Alan, Tuğba Başoğlu Tüylü [...]

Journal of Oncology Pharmacy Practice

Select article: A Phase I/II trial design when response is unobserved in subjects with dose-limiting toxicity

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Research article

First published 2016-4

A Phase I/II trial design when response is unobserved in subjects with dose-limiting toxicity

Thomas M Braun, Shan Kang, Jeremy MG Taylor

Statistical Methods in Medical Research

Select article: Modeling adverse event counts in phase I clinical trials of a cytotoxic agent

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Research article

First published 2018-8

Modeling adverse event counts in phase I clinical trials of a cytotoxic agent

Daniel G Muenz, Thomas M Braun, Jeremy MG Taylor

Clinical Trials

Select article: Reporting and impact of subsequent cycle toxicities in oncology phase I clinical trials

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Research article

First published 2024-4

Reporting and impact of subsequent cycle toxicities in oncology phase I clinical trials

Avina Rami, Steven G DuBois, Kevin Campbell

Clinical Trials

Select article: A No-Observed-Adverse-Effect Level of 1000 Mg/Kg in A 28-Day Repeated-Dose Study as a Limit Value for Acute Toxicity Testing

Free access

Research article

First published 1998-01

A No-Observed-Adverse-Effect Level of 1000 Mg/Kg in A 28-Day Repeated-Dose Study as a Limit Value for Acute Toxicity Testing

Moniek N. Pieters, Hester J. Kramer, Wout Slob

International Journal of Toxicology

Select article: Tolerance and Pharmacokinetics of Recombinant Human Endostatin Administered as Single-Dose or Multiple-Dose Infusions in Patients With Advanced Solid Tumors: A Phase I Clinical Trial

Open access

Research article

First published 2021

Tolerance and Pharmacokinetics of Recombinant Human Endostatin Administered as Single-Dose or Multiple-Dose Infusions in Patients With Advanced Solid Tumors: A Phase I Clinical Trial

Xu Wang, Yehui Shi, Yongsheng Jia [...]

Technology in Cancer Research & Treatment

Select article: The physical exam’s role in determining dose-limiting toxicity prior to immunochemotherapy administration in lymphoma

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Research article

First published 2023-4

The physical exam’s role in determining dose-limiting toxicity prior to immunochemotherapy administration in lymphoma

John S. Runge, Anna B. Brown, Tycel J. Phillips [...]

Journal of Oncology Pharmacy Practice

Select article: Phase I study of intraperitoneal bevacizumab for treating refractory malignant ascites

Open access

Research article

First published 2021-2

Phase I study of intraperitoneal bevacizumab for treating refractory malignant ascites

Furong Kou, Jifang Gong, Yan Li [...]

Journal of International Medical Research

Select article: EWOC 2.0: Interactive Software for Dose Escalation in Cancer Phase I Clinical Trials

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Research article

First published 2007-3

EWOC 2.0: Interactive Software for Dose Escalation in Cancer Phase I Clinical Trials

Zhiheng Xu, Mourad Tighiouart, André Rogatko

Therapeutic Innovation & Regulatory Science

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