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Research article

First published 2015-1-6

Metabolic Profiling of CHO-AβPP 695 Cells Revealed Mitochondrial Dysfunction Prior to Amyloid-β Pathology and Potential Therapeutic Effects of Both PPARγ and PPARα Agonisms for Alzheimer's Disease

Kai Lun Chang, Hai Ning Pee, Wee Pin Tan [...]

Journal of Alzheimer’s Disease

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Research article

First published 2004

Apolipoprotein is required for the formation of filamentous amyloid,but not for amorphous Aβ deposition,in an AβPP/PS double transgenic mouse model of Alzheimer's disease

David A. Costa, Lars N.G. Nilsson, Kelly R. Bales [...]

Journal of Alzheimer’s Disease

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Research article

First published 2001

Aβpp secretases are co-expressed with Aβpp in the pancreatic islets

David J. Figueroa, Xiao-Ping Shi, Stephen J. Gardell [...]

Journal of Alzheimer’s Disease

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Research article

First published 2002

The degradation of Aβ 25–35 by the serine protease plasmin is inhibited by aluminium

Olga V. Korchazhkina, Alison E. Ashcroft, Tamas Kiss [...]

Journal of Alzheimer’s Disease

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Research article

First published 2006

Neurine,an acetylcholine autolysis product,elevates secreted amyloid-β protein precursor and amyloid-β peptide levels,and lowers neuronal cell viability in culture: A role in Alzheimer's disease?

David Tweedie, Arnold Brossi, DeMoa Chen [...]

Journal of Alzheimer’s Disease

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Research article

First published 2004

The role of the endosomal/ lysosomal system in amyloid-beta production and the pathophysiology of Alzheimer's disease: Reexamining the spatial paradox from a lysosomal perspective

Stephen Howard Pasternak, John William Callahan, Don Joseph Mahuran

Journal of Alzheimer’s Disease

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Research article

First published 2022-04-05

BACE1 Overexpression Reduces SH-SY5Y Cell Viability Through a Mechanism Distinct from Amyloid-β Peptide Accumulation: Beta Prime-Mediated Competitive Depletion of sAβPP α

Lauren Owens, Joshua Bracewell, Alexandre Benedetto [...]

Journal of Alzheimer’s Disease

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Research article

First published 2016-11-1

Cyclic cis -Locked Phospho-Dipeptides Reduce Entry of AβPP into Amyloidogenic Processing Pathway

Carolyn L. Fisher, Ross J. Resnick, Soumya De [...]

Journal of Alzheimer’s Disease

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Research article

First published 2012-2-7

The BACE1-PSEN-AβPP Regulatory Axis has an Ancient Role in Response to Low Oxygen/Oxidative Stress

Seyyed Hani Moussavi Nik, Lachlan Wilson, Morgan Newman [...]

Journal of Alzheimer’s Disease

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Research article

First published 2017-9-18

Pazopanib Reduces Phosphorylated Tau Levels and Alters Astrocytes in a Mouse Model of Tauopathy

Monica Javidnia, Michaeline L. Hebron, Yue Xin [...]

Journal of Alzheimer’s Disease

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