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Research article

First published 2019

Choosing Estimands in Clinical Trials: Putting the ICH E9(R1) Into Practice

Bohdana Ratitch, James Bell, Craig Mallinckrodt [...]

Therapeutic Innovation & Regulatory Science

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Case report

First published 2019

Aligning Estimators With Estimands in Clinical Trials: Putting the ICH E9(R1) Guidelines Into Practice

C. H. Mallinckrodt, J. Bell, G. Liu [...]

Therapeutic Innovation & Regulatory Science

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Other

First published 2003-10

Impact of the ICH E9 Guideline Statistical Principles for Clinical Trials on the Conduct of Clinical Trials in Japan

Chihiro Hirotsu, Ludwig A. Hothorn

Therapeutic Innovation & Regulatory Science

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Brief report

First published 2019

Defining Efficacy Estimands in Clinical Trials: Examples Illustrating ICH E9(R1) Guidelines

Bohdana Ratitch, Niti Goel, Craig Mallinckrodt [...]

Therapeutic Innovation & Regulatory Science

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Research article

First published 2019-8

A constructive critique of the draft ICH E9 Addendum

Daniel O Scharfstein

Clinical Trials

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Research article

First published 2017-1

Current Practices in Choosing Estimands and Sensitivity Analyses in Clinical Trials

C. Fletcher, S. Tsuchiya, D.V. Mehrotra

Therapeutic Innovation & Regulatory Science

Open access

Review article

First published 2026-4

Use of estimands in cluster randomised trials: A review

Dongquan Bi, Andrew Copas, Brennan C Kahan

Clinical Trials

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Other

First published 2001-7

The All Randomized/Full Analysis Set (ICH E9)—May Patients Be Excluded from the Analysis? *

Stefan Lange

Therapeutic Innovation & Regulatory Science

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Research article

First published 2016-8

Seeking harmony: estimands and sensitivity analyses for confirmatory clinical trials

Devan V Mehrotra, Robert J Hemmings, Estelle Russek-Cohen [...]

Clinical Trials

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Other

First published 2004-1

The Choice of a for One-Sided Tests

Markus Neuhävser

Therapeutic Innovation & Regulatory Science

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