Sixteen Japanese Artemisia taxa were surveyed for flavonoid aglycones and glycosides. The leaves were rinsed with acetone and then extracted with MeOH. Isolated flavonoids were identified by UV, LC-MS, acid hydrolysis, ¹H and ¹³C NMR, and/or HPLC comparisons with authentic samples. Thus, nine flavone aglycones, apigenin (10), luteolin (5), chrysoeriol (11), hispidulin (6), jaseosidin (7), nepetin (15), sudachitin (8), luteolin 7-methyl ether (13) and eupatilin (14), three flavonol aglycones, axillarin (9), quercetin 3-methyl ether (16) and 5,7,4′-trihydroxy-3,6-dimethoxyflavone (12), one flavanone aglycone, pinocembrin (4), three dihydroflavonol aglycones, taxifolin (1), taxifolin 3-acetate (2) and padmatin (3) were found in their Artemisia taxa with the various combination. On the other hand, four flavonol glycosides, quercetin 3-O-rutinoside (17), quercetin 3-O-glucoside (18), patuletin 3-O-glucoside (19) and patuletin 3-O-rhamnosylglucoside (20), were isolated from a few Artemisia taxa.

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Flavonoid Aglycones and Glycosides from the Leaves of some Japanese Artemisia Species

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Flavonoid Aglycones and Glycosides from the Leaves of some Japanese Artemisia Species