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Research article

First published 2023-10

CRISPR/SaCas9-based gene editing rescues photoreceptor degeneration throughout a rhodopsin-associated autosomal dominant retinitis pigmentosa mouse model

Wei Du, Jiarui Li, Xin Tang [...]

Experimental Biology and Medicine

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Research article

First published 2024-12

Mutation-Specific CRISPR Targeting with SaCas9 and AsCas12a Restores Therapeutic Sensitivity in Treatment-Resistant Melanoma

Brett M. Sansbury, Sophia B. Masciarelli, Salma Kaouser [...]

The CRISPR Journal

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Research article

First published 2022-06

Reduction of Pre-Existing Adaptive Immune Responses Against SaCas9 in Humans Using Epitope Mapping and Identification

Xiaoting Shen, Qinru Lin, Zhiming Liang [...]

The CRISPR Journal

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Research article

First published 2018-12

Expanding the RNA-Guided Endonuclease Toolkit for Mouse Genome Editing

Louise Robertson, Daniel Pederick, Sandra Piltz [...]

The CRISPR Journal

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Research article

First published 2021-03

Rational Selection of CRISPR-Cas Triggering Homology-Directed Repair in Human Cells

Fanfan Li, Chenchen Zhou, Tianxiang Tu [...]

Human Gene Therapy

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Research article

First published 2020-08

Promoter Orientation within an AAV-CRISPR Vector Affects Cas9 Expression and Gene Editing Efficiency

Lewis E. Fry, Caroline F. Peddle, Marta Stevanovic [...]

The CRISPR Journal

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Research article

First published 2022-04

Green Fluorescent Protein Tagged Polycistronic Reporter System Reveals Functional Editing Characteristics of CRISPR-Cas

Fayu Yang, Hao Zhang, Shuo Cai [...]

The CRISPR Journal

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Research article

First published 2022-02

CRISPR-Cas9 Gene Editing Protects from the A53T-SNCA Overexpression-Induced Pathology of Parkinson's Disease In Vivo

Hyung Ho Yoon, Sunghyeok Ye, Sunhwa Lim [...]

The CRISPR Journal

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