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Research article

First published 2022-10

Inactivation of BACE1 increases expression of endothelial nitric oxide synthase in cerebrovascular endothelium

Tongrong He, Livius V d’Uscio, Ruohan Sun [...]

Journal of Cerebral Blood Flow & Metabolism

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Research article

First published 2012-2-7

The BACE1-PSEN-AβPP Regulatory Axis has an Ancient Role in Response to Low Oxygen/Oxidative Stress

Seyyed Hani Moussavi Nik, Lachlan Wilson, Morgan Newman [...]

Journal of Alzheimer’s Disease

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Research article

First published 2005

Novel mutations introduced at the β-site of amyloid β protein precursor enhance the production of amyloid β peptide by BACE1 in vitro and in cells

Xiao-Ping Shi, Katherine Tugusheva, James E. Bruce [...]

Journal of Alzheimer’s Disease

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Research article

First published 2009

Lifespan Profiles of Alzheimer's Disease-Associated Genes and Products in Monkeys and Mice

Remi Dosunmu, Jinfang Wu, Lina Adwan [...]

Journal of Alzheimer’s Disease

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Review article

First published 2024-10-18

BACE1 Inhibitors for Alzheimer’s Disease: Current Challenges and Future Perspectives

Judite R.M. Coimbra, Rosa Resende, José B.A. Custódio [...]

Journal of Alzheimer’s Disease

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Research article

First published 2010-6-13

Converging Pathways of Chromogranin and Amyloid Metabolism in the Brain

Niklas Mattsson, Per Johansson, Oskar Hansson [...]

Journal of Alzheimer’s Disease

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Research article

First published

Lamotrigine Reduces β-Site AβPP-Cleaving Enzyme 1 Protein Levels Through Induction of Autophagy

Hao Wu, Mei-Hong Lu, Wang Wang [...]

Journal of Alzheimer’s Disease

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Research article

First published 2020-08-18

New BACE1 Chimeric Peptide Inhibitors Selectively Prevent AβPP-β Cleavage Decreasing Amyloid-β Production and Accumulation in Alzheimer’s Disease Models

Rosa Resende, Marisa Ferreira-Marques, Patrícia Moreira [...]

Journal of Alzheimer’s Disease

Open access

Research article

First published 2011-9-9

The Cysteine Protease Inhibitor,E64d,Reduces Brain Amyloid-β and Improves Memory Deficits in Alzheimer's Disease Animal Models by Inhibiting Cathepsin B,but not BACE1,β-Secretase Activity

Gregory Hook, Vivian Hook, Mark Kindy

Journal of Alzheimer’s Disease

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Research article

First published 2010-9-28

Changes in Cognition and Amyloid-β Processing with Long Term Cholesterol Reduction using Atorvastatin in Aged Dogs

M. Paul Murphy, Jacqueline Morales, Tina L. Beckett [...]

Journal of Alzheimer’s Disease

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