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Research article

First published 2011-5-30

The γ-Secretase Modulator CHF5074 Restores Memory and Hippocampal Synaptic Plasticity in Plaque-Free Tg2576 Mice

Claudia Balducci, Bisan Mehdawy, Lydia Mare [...]

Journal of Alzheimer’s Disease

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Research article

First published 2010-10-1

Caveolin-1 Regulates γ-Secretase-Mediated AβPP Processing by Modulating Spatial Distribution of γ-Secretase in Membrane

Arun Kapoor, Wen-Ming Hsu, Bo-Jeng Wang [...]

Journal of Alzheimer’s Disease

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Review article

First published 2012-9-11

γ-Secretase Modulator in Alzheimer's Disease: Shifting the End

Weiming Xia, Stephen T. Wong, Eugene Hanlon [...]

Journal of Alzheimer’s Disease

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Research article

First published 2010-3-24

CHF5074,a Novel γ-Secretase Modulator,Restores Hippocampal Neurogenesis Potential and Reverses Contextual Memory Deficit in a Transgenic Mouse Model of Alzheimer's Disease

Bruno P. Imbimbo, Luciana Giardino, Sandra Sivilia [...]

Journal of Alzheimer’s Disease

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Research article

First published

γ-Secretase Modulators and Inhibitors Induce Different Conformational Changes of Presenilin 1 Revealed by FLIM and FRET

Xin Wang, Jin Cui, Wei Li [...]

Journal of Alzheimer’s Disease

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Research article

First published 2010-9-2

Acute Effect on the Aβ Isoform Pattern in CSF in Response to γ-Secretase Modulator and Inhibitor Treatment in Dogs

Erik Portelius, Bianca Van Broeck, Ulf Andreasson [...]

Journal of Alzheimer’s Disease

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Review article

First published 2014-12-2

Inhibition of Glutaminyl Cyclase Ameliorates Amyloid Pathology in an Animal Model of Alzheimer's Disease via the Modulation of γ-Secretase Activity

Hyundong Song, Yu Jin Chang, Minho Moon [...]

Journal of Alzheimer’s Disease

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Brief report

First published 2013-11-25

Modulation of Amyloid-β Production by Leukotriene B 4 via the γ-Secretase Pathway

Yash B. Joshi, Antonio Di Meco, Domenico Praticó

Journal of Alzheimer’s Disease

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Research article

First published 2011-11-29

γ-Secretase-Mediated Regulation of Neprilysin: Influence of Cell Density and Aging and Modulation by Imatinib

Charlotte Bauer, Raphaëlle Pardossi-Piquard, Julie Dunys [...]

Journal of Alzheimer’s Disease

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Research article

First published 2013-3-29

Aftins Increase Amyloid-β 42,Lower Amyloid-β 38,and Do Not Alter Amyloid-β 40 Extracellular Production in vitro: Toward a Chemical Model of Alzheimer's Disease?

Arnaud Hochard, Nassima Oumata, Karima Bettayeb [...]

Journal of Alzheimer’s Disease

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