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Research article

First published 2011-9-9

The Cysteine Protease Inhibitor,E64d,Reduces Brain Amyloid-β and Improves Memory Deficits in Alzheimer's Disease Animal Models by Inhibiting Cathepsin B,but not BACE1,β-Secretase Activity

Gregory Hook, Vivian Hook, Mark Kindy

Journal of Alzheimer’s Disease

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Research article

First published 2011-7-1

Increased CSF-BACE1 Activity Associated with Decreased Hippocampus Volume in Alzheimer's Disease

Michael Ewers, Xin Cheng, Zhenyu Zhong [...]

Journal of Alzheimer’s Disease

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Research article

First published 2012-2-7

The BACE1-PSEN-AβPP Regulatory Axis has an Ancient Role in Response to Low Oxygen/Oxidative Stress

Seyyed Hani Moussavi Nik, Lachlan Wilson, Morgan Newman [...]

Journal of Alzheimer’s Disease

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Research article

First published 2022-01-04

Anti-Stroke Chinese Herbal Medicines Inhibit Abnormal Amyloid-β Protein Precursor Processing in Alzheimer’s Disease

Yan Tan, Jiani Zhang, Ke Yang [...]

Journal of Alzheimer’s Disease

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Research article

First published 2010-9-28

Changes in Cognition and Amyloid-β Processing with Long Term Cholesterol Reduction using Atorvastatin in Aged Dogs

M. Paul Murphy, Jacqueline Morales, Tina L. Beckett [...]

Journal of Alzheimer’s Disease

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Research article

First published 2016-12-20

Protein Expression of BACE1 is Downregulated by Donepezil in Alzheimer’s Disease Platelets

Tamires Alves Sarno, Leda Leme Talib, Helena Passarelli Giroud Joaquim [...]

Journal of Alzheimer’s Disease

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Research article

First published 2011-12-12

Amyloid-β 42 Activates the Expression of BACE1 Through the JNK Pathway

Michela Guglielmotto, Debora Monteleone, Luca Giliberto [...]

Journal of Alzheimer’s Disease

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Research article

First published 2012-4-16

Deletion of the Cathepsin B Gene Improves Memory Deficits in a Transgenic Alzheimer's Disease Mouse Model Expressing AβPP Containing the Wild-Type β-Secretase Site Sequence

Mark S. Kindy, Jin Yu, Hong Zhu [...]

Journal of Alzheimer’s Disease

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Research article

First published 2011-6-14

PPARγ Co-Activator-1α (PGC-1α) Reduces Amyloid-β Generation Through a PPARγ-Dependent Mechanism

Loukia Katsouri, Callum Parr, Nenad Bogdanovic [...]

Journal of Alzheimer’s Disease

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Research article

First published

Genetic Variation in δ -Opioid Receptor Associates with Increased β- and γ -Secretase Activity in the Late Stages of Alzheimer’s Disease

Timo Sarajärvi, Mikael Marttinen, Teemu Natunen [...]

Journal of Alzheimer’s Disease

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