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Research article

First published 2025-2

In silico study of selected alkaloids as dual inhibitors of β- and γ-secretases for Alzheimer's disease

Isreal Ayobami Onifade, Haruna Isiyaku Umar, Abdullahi Tunde Aborode [...]

Journal of Alzheimer’s Disease

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Research article

First published 2011-2

Reduction of β-Amyloid Deposits by γ-Secretase Inhibitor is Associated with the Attenuation of Secondary Damage in the Ipsilateral Thalamus and Sensory Functional Improvement after Focal Cortical Infarction in Hypertensive Rats

Yusheng Zhang, Shihui Xing, Jian Zhang [...]

Journal of Cerebral Blood Flow & Metabolism

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Research article

First published 2016-4-12

Inhibition of Cholesterol Biosynthesis Reduces γ -Secretase Activity and Amyloid-β Generation

Yoonhee Kim, Chaeyoung Kim, Hye Young Jang [...]

Journal of Alzheimer’s Disease

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Research article

First published 2014-12-23

Auraptene Increases the Production of Amyloid-β via c-Jun N-Terminal Kinase-Dependent Activation of γ-Secretase

Cha-Gyun Jung, Kyung-Ok Uhm, Hirofumi Horike [...]

Journal of Alzheimer’s Disease

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Review article

First published 2009

γ-Secretase Catalyzes Sequential Cleavages of the AβPP Transmembrane Domain

Xuemin Xu

Journal of Alzheimer’s Disease

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Review article

First published 2021-05-04

Selective Secretase Targeting for Alzheimer’s Disease Therapy

Alvaro Miranda, Enrique Montiel, Henning Ulrich [...]

Journal of Alzheimer’s Disease

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Research article

First published 2017-12-19

Increased Foxo3a Nuclear Translocation and Activity is an Early Neuronal Response to βγ-Secretase-Mediated Processing of the Amyloid-β Protein Precursor: Utility of an AβPP-GAL4 Reporter Assay

Bernard M. Law, Amy L. Guest, Matthew W. J. Pullen [...]

Journal of Alzheimer’s Disease

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Research article

First published 2010-9-2

Acute Effect on the Aβ Isoform Pattern in CSF in Response to γ-Secretase Modulator and Inhibitor Treatment in Dogs

Erik Portelius, Bianca Van Broeck, Ulf Andreasson [...]

Journal of Alzheimer’s Disease

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Review article

First published 2011-4-22

Activation of the α-Secretase Processing of AβPP as a Therapeutic Approach in Alzheimer's Disease

Bruno Vincent, Piyarat Govitrapong

Journal of Alzheimer’s Disease

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Review article

First published 2012-9-11

γ-Secretase Modulator in Alzheimer's Disease: Shifting the End

Weiming Xia, Stephen T. Wong, Eugene Hanlon [...]

Journal of Alzheimer’s Disease

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